Is weight loss for women really possible with gene editing? A group of medical scientists at the University of Washington did a study on laboratory mice that were obese. They then gave them genetic instructions – telling them to eat only lean red meat and to eat a low calorie diet. What they found was that these mice turned white fat into brown fat. This is one of the first studies to show that gene editing can help you lose weight.
The study was led by J. Michael Weiss, Ph.D., a professor of molecular biology and microbiology. He is also a member of the faculty at Stanford University School of Medicine. The paper published in the Nature Genetics journal shows that the genes responsible for producing the brown adipose tissue in the body’s cells actually became faulty. When the genes are defective, the brown fat cells cannot function properly and become over weight.
So, if the faulty genes are passed on, how can we get rid of them and still lose weight? There is a solution. Scientists have recently come up with an idea to use gene editing to correct the problem. A new technique allows a doctor to make changes to your genes and then inject the new changes directly into your body. The new tissue will burn energy differently than your white fat and your body will turn back to its old beige fat.
Over time, your white fat cells will become brown fat cells. When your brown adipose tissue cells turn into beige fat, your weight will become unmanageable. The new cells that you have will burn calories and fats much differently than your old fat cells. Because this procedure is non-invasive, your doctor should be able to make frequent adjustments to your diet and exercise routine.
In addition to using gene editing to correct genetic problems, scientists have developed another way to turn beige fat into brown fat. Scientists have discovered that some plants contain a substance that causes the production of brown fat. They call this substance monounsaturated fatty acid or MUFA. The Japanese use this type of fat in their rice paddies and people in Japan have been eating it for many years without any health complications.
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Scientists believe that there are about 15 different types of PUFA. Some scientists have even identified a new type of PUFA called rutin that may be helpful in preventing obesity. The one thing that all of these PUFAs have in common is that they have a molecular structure that makes it easier for them to be metabolized by the liver. Brown fat also appears to be more resistant to melting than white fat. It can store more energy than beige adipose tissue, which may explain why women who burn more brown fat tend to have more energy than women who burn beige adipose tissue.
One way to turn brown fat into beige fat is by inhibiting the ability of the enzyme fto gene to break down the PUFA. Since the fto gene is found mostly in brown fat, the best place to try to block it is in the brown fat adipose tissue. A company in New Zealand has found a unique way to inhibit the fto gene. By introducing a new genetic insertion into human cells, they have managed to completely block the fto gene. This is probably the safest way to prevent obesity.Conclusion
Another way to turn white fat into brown fat is to increase the production of adiponectin. Adiponectin is produced by brown fat, and is believed to reduce weight due to its ability to increase your metabolism. The Japanese have been using adiponectin injections for years to turn white fat into brown fat.
Source from : https://thehealthmags.com
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