================================================================================
                     U.S. SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                   FORM 10-QSB
                                -----------------

(Mark One)

[x]  QUARTERLY  REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES  EXCHANGE ACT
     OF 1934.

For the quarterly period ended September 30, 2005

[ ]  TRANSITION REPORT UNDER SECTION 13 OR 15(d) OF THE SECURITIES  EXCHANGE ACT
     OF 1934.

For the transition period from  _________ to ____________

Commission File Number: 000-23-661
                                -----------------

                       ROCKWELL MEDICAL TECHNOLOGIES, INC.
        (Exact name of small business issuer as specified in its charter)

            Michigan                                     38-3317208
--------------------------------            ------------------------------------
(State or other  jurisdiction of            (I.R.S. Employer Identification No.)
 incorporation or organization)



                                30142 Wixom Road
                              Wixom, Michigan 48393
                   ------------------------------------------
                    (Address of principal executive offices)

                                 (248) 960-9009
                   ------------------------------------------
                           (Issuer's telephone number)

--------------------------------------------------------------------------------
   (Former name, former address and former fiscal year, if changed since last
                                     report)

     Check  whether  the issuer:  (1) filed all reports  required to be filed by
Section 13 or 15(d) of the  Exchange  Act during the past 12 months (or for such
shorter period that the  registrant was required to file such reports),  and (2)
has been subject to such filing  requirements for the past 90 days.
Yes [X] No [ ]

     Indicate  by check mark  whether  the  issuer  is a shell  company  (as
defined by Rule 12b-2 of the Exchange Act. Yes [ ] No [X]

     State the number of shares  outstanding of each of the issuer's  classes of
common  equity  as of the  latest  practicable  date:  8,790,067  Common  Shares
outstanding as of November 8, 2005.

Transitional Small Business Disclosure Format (Check one):
Yes [ ]  No [ X ]

================================================================================



                         PART I - FINANCIAL INFORMATION

ITEM 1. FINANCIAL STATEMENTS.

               ROCKWELL MEDICAL TECHNOLOGIES, INC. AND SUBSIDIARY

                           CONSOLIDATED BALANCE SHEETS

                 As of September 30, 2005 and December 31, 2004

                                 (Whole Dollars)

                                   (Unaudited)


                                                                               September 30,   December 31,
                                                                                   2005            2004
                                                                               ------------    ------------
                                                                                         
                                     ASSETS
Cash and  Cash Equivalents .................................................   $    451,325    $    166,195
Restricted Cash Equivalents ................................................          8,662           8,662
Accounts Receivable, net of a reserve of $53,000 in 2005 and $44,500 in 2004      2,702,181       2,302,093
Inventory ..................................................................      2,062,523       1,652,457
Other Current Assets .......................................................        669,020         111,630
                                                                               ------------    ------------
    Total Current Assets ...................................................      5,893,711       4,241,037

Property and Equipment, net ................................................      2,068,157       2,048,665
Intangible Assets ..........................................................        400,499         369,508
Goodwill ...................................................................        920,745         920,745
Other Non-current Assets ...................................................        128,742         120,597
                                                                               ------------    ------------

     TOTAL ASSETS ..........................................................   $  9,411,854    $  7,700,552
                                                                               ============    ============

                      LIABILITIES AND SHAREHOLDERS' EQUITY

Short Term Borrowings ......................................................   $  1,400,000    $    452,682
Notes Payable & Capitalized Lease Obligations ..............................        449,608         389,602
Accounts Payable ...........................................................      1,503,104       2,124,679
Customer Deposits ..........................................................      1,078,345          11,005
Accrued Liabilities ........................................................        400,414         481,587
                                                                               ------------    ------------
     Total Current Liabilities .............................................      4,831,471       3,459,555

Long Term Notes Payable & Capitalized Lease Obligations ....................        566,051         818,678

     Shareholders' Equity:
Common  Share, no par value, 8,697,384 and 8,556,531 shares issued and
outstanding ................................................................     12,146,094      11,870,909
Common Share Purchase Warrants, 3,700,000 and 3,761,071 shares issued and
outstanding ................................................................        286,130         320,150
Accumulated Deficit ........................................................     (8,417,892)     (8,768,740)
                                                                               ------------    ------------
      Total Shareholders' Equity ...........................................      4,014,332       3,422,319
                                                                               ------------    ------------
     TOTAL LIABILITIES AND SHAREHOLDERS' EQUITY ............................   $  9,411,854    $  7,700,552
                                                                               ============    ============


   The accompanying notes are an integral part of the consolidated financial
                                  statements.

                                       2



               ROCKWELL MEDICAL TECHNOLOGIES, INC. AND SUBSIDIARY

                         CONSOLIDATED INCOME STATEMENTS

  For the three and nine months ended September 30, 2005 and September 30, 2004

                                 (WHOLE DOLLARS)

                                   (Unaudited)



                                       Three Months     Three Months     Nine Months      Nine Months
                                          Ended            Ended            Ended            Ended
                                      Sept. 30, 2005   Sept. 30, 2004   Sept. 30, 2005   Sept. 30, 2004
                                      --------------   --------------   --------------   --------------
                                                                             
SALES .............................    $ 7,828,262      $ 4,473,872      $21,238,803      $13,164,640
Cost of Sales .....................      6,868,274        3,753,177       18,798,954       11,066,748
                                       -----------      -----------      -----------      -----------
  GROSS PROFIT ....................        959,988          720,695        2,439,849        2,097,892
Selling, General and Administrative        758,819          606,304        2,094,945        1,759,692
                                       -----------      -----------      -----------      -----------
  OPERATING INCOME ................        201,169          114,391          344,904          338,200
 Other Income .....................           --               --            137,468             --
Interest Expense, net .............         44,992           49,114          131,524          138,082
                                       -----------      -----------      -----------      -----------
  Net Income ......................    $   156,177      $    65,277      $   350,848      $   200,118
                                       ===========      ===========      ===========      ===========

BASIC EARNINGS PER SHARE ..........    $       .02      $       .01      $       .04      $       .02

DILUTED  EARNINGS  PER SHARE ......    $       .02      $       .01      $       .04      $       .02



   The accompanying notes are an integral part of the consolidated financial
                                  statements.

                                       3



               ROCKWELL MEDICAL TECHNOLOGIES, INC. AND SUBSIDIARY

                      CONSOLIDATED STATEMENTS OF CASH FLOWS

       For the nine months ended September 30, 2005 and September 30, 2004

                                 (WHOLE DOLLARS)
                                   (Unaudited)


                                                                      2005            2004
                                                                 ------------    ------------
                                                                           
CASH FLOWS FROM OPERATING ACTIVITIES:
  NET INCOME .................................................   $    350,848    $    200,118
  Adjustments To Reconcile Net Income To Net Cash Used For
     Operating Activities:
     Depreciation and Amortization ...........................        516,217         462,250
                                                 
     Changes in Assets and Liabilities:
       (Increase) in Accounts Receivable .....................       (400,088)       (133,302)
       (Increase) in Inventory ...............................       (410,066)        (87,421)
       (Increase) in Other Assets ............................       (565,535)        (37,795)
       (Decrease) Increase in Accounts Payable ...............       (621,575)        268,769
       Increase in Customer Deposits .........................      1,067,340            --         
       (Decrease) Increase in Other Liabilities ..............        (81,173)        116,898
                                                                 ------------    ------------
          Changes in Assets and Liabilities ..................     (1,011,097)        127,149
                                                                 ------------    ------------
           CASH PROVIDED BY OPERATING ACTIVITIES .............       (144,032)        789,517        

CASH FLOWS FROM INVESTING ACTIVITIES:
     Purchase of Equipment ...................................       (445,813)       (277,149)
     Purchase of Intangible Assets ...........................        (56,478)        (75,000)
                                                                 ------------    ------------
           CASH (USED IN) INVESTING ACTIVITIES ...............       (502,291)       (352,149)

CASH FLOWS FROM FINANCING ACTIVITIES:
     Proceeds from Borrowing on Line of Credit ...............      5,537,395      12,147,230
       Payments on Line of Credit ............................     (4,590,077)    (12,415,374)     
       Payments on Notes Payable and Capital Lease Obligations       (257,030)       (246,713)
       Issuance of Common Shares .............................        241,165          32,876
                                                                 ------------    ------------
            CASH PROVIDED BY (USED IN) FINANCING ACTIVITIES ..        931,453        (481,981)

INCREASE IN CASH .............................................        285,130         (44,613)
CASH AT BEGINNING OF PERIOD ..................................        166,195         106,639
                                                                 ------------    ------------
CASH AT END OF PERIOD ........................................   $    451,325    $     62,026
                                                                 ============    ============
     Supplemental Cash Flow Disclosure:
         Interest Paid .......................................   $    131,621    $    138,166
                                                                 ============    ============
     Non-Cash Investing and Financing Activity -
         Equipment Acquired Under Capital Lease Obligations ..   $     64,409    $    209,648
                                                                 ============    ============


   The accompanying notes are an integral part of the consolidated financial
                                  statements.

                                       4



               ROCKWELL MEDICAL TECHNOLOGIES, INC. AND SUBSIDIARY

                   NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

1. DESCRIPTION OF BUSINESS

     We manufacture,  sell and distribute  hemodialysis  concentrates  and other
ancillary  medical  products and supplies used in the treatment of patients with
kidneys that do not function properly. We supply our products to medical service
providers  who treat  patients  with kidney  disease.  Our  products are used to
cleanse  patients'  blood and  replace  nutrients  during  the  kidney  dialysis
process. We primarily sell our products in the United States.

     We are  regulated by the United  States Food and Drug  Administration  (the
"FDA") under the Federal Drug and  Cosmetics  Act, as well as by other  Federal,
state and local  agencies.  We have  received  510(k)  approval  from the FDA to
market hemodialysis  solutions and powders. We also have 510(k) approval to sell
our  Dri-Sate(R)  Dry Acid  Concentrate  product line and  Dri-Sate(R)  Dry Acid
Mixing System.

2. SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

BASIS OF PRESENTATION

     Our consolidated financial statements include our accounts and the accounts
of our wholly owned subsidiary,  Rockwell Transportation,  Inc. All intercompany
balances and transactions have been eliminated.

     In the opinion of our management,  all adjustments have been included which
are  necessary to make the financial  statements  not  misleading.  All of these
adjustments  that  are  material  are of a  normal  and  recurring  nature.  Our
operating  results for the three month period ended  September  30, 2005 are not
necessarily  indicative  of the  results  to be  expected  for the  year  ending
December 31, 2005. You should read our unaudited  interim  financial  statements
together with the financial  statements and related footnotes for the year ended
December  31, 2004  included in our Annual  Report on Form 10-KSB for the fiscal
year ended  December 31, 2004.  Our Annual  Report on Form 10-KSB for the fiscal
year  ended  December  31,  2004  includes  a  description  of  our  significant
accounting policies.

REVENUE RECOGNITION

     We recognize  revenue at the time we transfer  title to our products to our
customers consistent with generally accepted accounting  principles.  Generally,
we recognize revenue when our products are delivered to our customer's  location
consistent  with our terms of sale.  In most  instances  title for goods shipped
internationally  transfers  to  the  buyer  once  it  leaves  our  facility  and
therefore, we recognize revenue upon shipment to foreign customers.

     We require certain customers,  mostly international  customers,  to pay for
product prior to the transfer of title to the customer.  Deposits  received from
customers and payments in advance for orders are recorded as  liabilities  under
Customer  Deposits  until such time as orders are filled and title  transfers to
the customer  consistent  with our terms of sale.  At September 30, 2005, we had
customer deposits of $1,078,345.

EARNINGS PER SHARE

     We computed our basic  earnings  per share using  weighted  average  shares
outstanding for each respective period.  Diluted earnings per share also reflect
the  weighted  average  impact  from the  date of  issuance  of all  potentially
dilutive

                                       5

securities, consisting of stock options and common share purchase warrants,
unless inclusion would have had an antidilutive effect. Actual weighted average
shares outstanding used in calculating basic and diluted earnings per share
were:



                                       Three months ended             Nine months ended
                                          September 30,                 September 30,
                                     ------------------------      ------------------------
                                       2005           2004           2005           2004
                                     ---------      ---------      ---------      ---------
                                                                      
Basic Weighted Average Shares
  Outstanding                        8,680,952      8,551,814      8,633,866      8,543,874
Effect of Dilutive Securities          714,845        604,363        681,160        728,428
                                     ---------      ---------      ---------      ---------
Diluted Weighted Average Shares
  Outstanding                        9,395,797      9,156,177      9,315,026      9,272,302
                                     =========      =========      =========      =========


      Our reported and pro forma information for the three and nine months ended
September 30:



                                                Three             Three             Nine               Nine
                                                months           months            months             months
                                                ended             ended             ended              ended
                                             September 30,    September 30,     September 30,      September 30,
                                                 2005             2004              2005               2004
                                            --------------   --------------     --------------     --------------
                                                                                      
As reported net income (loss) available
  to common shareholders                        $156,177         $ 65,277          $350,849         $200,118
Less: Stock based compensation
  expense determined under the
  fair market value method,
  net of tax                                     145,120          219,864           476,953          659,593
                                                --------        ---------         ---------        ---------
Pro forma net income (loss)                     $ 11,057        ($154,587)        ($126,104)       ($459,475)
                                                ========        =========         =========        =========
As reported basic earnings  per share           $   0.02         $   0.01          $   0.04         $   0.02
As reported diluted earnings  per share         $   0.02         $   0.01          $   0.04         $   0.02

Pro forma earnings (loss) per share and
  diluted earnings (loss)  per share            $   0.00        ($   0.02)        ($   0.01)       ($   0.05)


3. LINE OF CREDIT

      On March 29, 2005, we entered into a new line of credit with a financial
institution. The loan agreement provides for revolving borrowings by us of up to
$2,750,000. We are permitted to borrow up to 80% of eligible accounts receivable
and 40% of eligible inventory up to $600,000. Borrowings under the loan
agreement are secured by accounts receivable, inventory and certain other
assets. The annual interest rate payable on revolving borrowings under the loan
agreement is the lender's prime rate plus 75 basis points. The lender's
commitment to make revolving borrowings under the loan agreement expires on
March 31, 2006. As of September 30, 2005, we had borrowed $1,400,000 under this
line of credit.

4. OTHER INCOME

      We were the plaintiff in certain litigation that was settled in the first
quarter of 2005. Since we have realized the full proceeds of the settlement,
which totaled approximately $241,000, we have recognized $137,468 of other
income from this settlement in the first quarter of 2005. A portion of the cash
received was from the exercise of stock options by the defendant during the
first quarter of 2005 which totaled $103,750.


                                       6



5. WARRANT EXCHANGE

      On July 29, 2005, we filed with the Securities and Exchange Commission
(the "SEC") a registration statement on Forms S-4 and SB-2 (the "Registration
Statement") with respect to an offer to exchange new common share purchase
warrants expiring January 26, 2006 with an exercise price of $3.90 ("New
Warrants") for each of the 3,625,000 currently outstanding common share purchase
warrants expiring January 26, 2006 with an exercise price of $4.50 ("Old
Warrants"). The SEC declared the Registration Statement effective on October 20,
2005. Old Warrant holders must tender their Old Warrants by November 28, 2005 to
participate in the exchange. Both Old and New Warrants expire January 26, 2006.


ITEM 2. MANAGEMENT'S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS
        OF OPERATIONS

      Some of the statements in this report are forward-looking statements.
These forward-looking statements include statements relating to our performance
in this Management's Discussion and Analysis of Financial Condition and Results
of Operations. In addition, we may make forward-looking statements in future
filings with the Securities and Exchange Commission and in written material,
press releases and oral statements. Forward-looking statements include
statements regarding the intent, belief or current expectations of us or our
officers, including statements preceded by, followed by or including
forward-looking terminology such as "may," "might," "will," "should," "believe,"
"expect," "anticipate," "estimate," "continue," "predict," "forecast,"
"projected," or similar expressions, with respect to various matters.

      Our actual results might differ materially from those projected in the
forward-looking statements depending on various important factors. These
important factors include the cost of obtaining FDA approval to market our new
iron supplemented dialysate product, the challenges associated with developing
new products, the uncertainty of acceptance of our products by the hemodialysis
community, competition in our market, and the other factors discussed under the
caption "Risk Factors" in our Registration Statement on Form SB-2 (file no.
333-31991) effective January 26, 1998, our Registration Statement on Forms SB-2
and S-4(file no. 333-127048), effective October 20, 2005, and elsewhere in our
public filings and in this report, all of which constitute cautionary statements
identifying important factors with respect to the forward-looking statements,
including risks and uncertainties, that could cause actual results to differ
materially from those in the forward-looking statements.

      All forward-looking statements in this report are based on information
available to us on the date of this report. We do not undertake to update any
forward-looking statements that may be made by us or on our behalf in this
report or otherwise.

OVERVIEW

      We operate in a single business segment: the manufacture and distribution
of hemodialysis concentrates, dialysis kits and ancillary products used in the
dialysis process. Our business has gained market share each year and our sales
have grown each year since our inception in 1996. In 2004, our revenue grew 20%
to $17.9 million and we earned $211,000. We increased our sales by over 61% for
the first nine months of 2005 compared to first nine months of last year. Our
net earnings were $351,000 in the first nine months of 2005 or $.04 per share.

      We believe that our core concentrate and supply business can continue to
be profitable; however, the dialysis supply market is very competitive and we
compete against companies that have substantially greater resources than we
have. We expect to continue growing our business while executing our strategic
plan to expand our product lines, expand our geographic reach and to develop our
proprietary technology. We expanded our operations in the Southeastern United
States by adding a third manufacturing facility in March of 2005. We have
increased our plant capacity in order to position ourselves to take advantage of
accelerated growth potential in our market. In the short run, we expect that
these additional costs will reduce our gross profit margins until we
successfully increase facility production volumes.


                                        7


      The dialysis industry is highly concentrated with several large clinic
chains representing the majority of the industry. We expect that the
consolidation of large and regional dialysis service providers will continue in
the future. Our largest customer, DaVita, Inc., the second largest dialysis
treatment provider in the United States, recently completed the acquisition of
the dialysis clinic business of Gambro Healthcare U.S. in October, the third
largest dialysis treatment provider in the United States. How this transaction
may impact our market or our results is not clear at this time; however, we
believe these events may prove beneficial in our business development efforts.

      We are seeking to gain FDA approval for our iron supplemented dialysate
product (which we also refer to as dialysate iron). We believe our iron
supplemented dialysate product has the potential to compete in the iron
maintenance therapy market. If we are successful in introducing our dialysate
iron product, we believe it is possible that we may also increase our market
share for the other products we sell. The cost to obtain regulatory approval for
a drug in the United States is substantial and we expect that the development
costs of our iron supplemented dialysate product will require us to raise
additional funds or collaborate with a strategic partner. These substantial
costs include those expected to be incurred in order to conduct required
clinical trials and to obtain marketing approval which costs may offset some or
all of any profits generated from sales of our existing products during the
approval process, and we may incur losses. We expect the approval process to
take between two and three years and there is no assurance we will be
successful.

RESULTS OF OPERATIONS FOR THE THREE AND NINE MONTHS ENDED SEPTEMBER 30, 2005

      Our sales in the third quarter of 2005 were $7,828,262 and increased by
75%, or $3,354,000, over the third quarter of 2004. Sales of our dialysis
concentrates represented 72% of our sales in the third quarter of 2005 and
increased 45.7% over the third quarter of 2004. Sales of our kits and ancillary
products increased by $1.6 million largely as a result of an increase in
dialysis kit sales primarily due to the purchase order described below.

      We received a significant purchase order from a single distributor for
dialysis products totaling $6,500,000 late in the first quarter of 2005 and
fulfilled approximately $2.4 million in the third quarter, which is included in
our sales results. We anticipate filling the remaining $960,000 of this purchase
order during the fourth quarter of 2005. We anticipate that similar purchase
orders may recur in the future. However, it is possible that they may not recur
in the future or repeat in each succeeding period.

      Gross profit was $959,988 in the third quarter of 2005, which represented
an increase of 33.2%, or $239,000, from the third quarter of 2004. Sequentially,
third quarter 2005 gross profit increased $150,000 over the second quarter of
2005, with gross profit margins improving by 1.9 percentage points from 10.4% in
the second quarter of 2005 to 12.3% in the third quarter of 2005. Our margins
had dropped earlier in 2005 due to a combination of temporary and recurring cost
increases. We realized improvements in gross profit margins in the third quarter
as temporary cost increases from our expansion efforts in the first half of 2005
did not recur in the third quarter.

      Our overall gross profit margins in the third quarter of 2005 were 12.3%
as compared to 16.1% in the third quarter of 2004. There were several factors,
both recurring and non-recurring, contributing to the reduction in gross profit
margins compared to the year earlier period including the expansion of our
production operations, higher product delivery costs due to fuel increases and
higher costs for equipment maintenance caused by increased production volumes.

      We made an investment in the geographic expansion of our business in order
to position the Company to take advantage of new business opportunities in our
market. In March of 2005, we added a third manufacturing facility in the
Southeastern United States that increased our costs of operation. We moved
certain production, related to business in that region, to the new facility from
our other facilities, which added flexibility at our other facilities to absorb
additional volume growth. As a result, we added additional operating costs which
have not been completely offset by higher production volumes. The current
facility in the Southeast is being leased under a short term lease agreement
that is set to expire on December 10, 2005. We may renew the lease on this
facility or we may relocate to another facility if we do not renew our lease at
our current facility. How a lease renewal or relocation of our facility may
impact our operating costs is not clear at this time. We anticipate that having
a facility in the Southeastern United States will enable us to realize
improvements in


                                       8


distribution efficiencies and will mitigate the negative impact from supplying
the Southeastern United States from our other facilities.

      Overall, our recurring operating costs have increased and have reduced our
gross profit margins by over two percentage points compared to the third quarter
of 2004. Cost increases included higher fuel costs for delivery, which we
estimate to have decreased gross profit margins by 1.5 percentage points in the
third quarter. Other increases in cost include additional production resources
that will provide us with additional speed and flexibility in handling new
business in the future.

      Selling, general and administrative expense as a percent of sales in the
third quarter of 2005 decreased to 9.7% of sales from 13.5% of sales in the
third quarter of 2004 or an improvement of 3.8% of sales. Our selling, general
and administrative expenses increased $152,515, or 25.2%, compared to the third
quarter of 2004. The majority of the cost increase was due to additional
personnel resources and internal information technology infrastructure added to
handle increased transaction activity associated with our 61% sales increase in
the first nine months of 2005. Our third quarter 2005 spending on the dialysate
iron project of $74,000 was an increase of $35,000 over the third quarter of
last year.

      Operating income in the third quarter of 2005 was $201,169, which was an
improvement in profitability of 76%, or $87,000, compared to the third quarter
of 2004. Operating income to sales was 2.6% in both periods.

      Net interest expense for the third quarter of 2005 was $44,992 and
decreased $4,087 compared to the third quarter of last year largely as a result
of lower average borrowings and lower effective interest rates under our new
line of credit.

      Net Income for the third quarter of 2005 was $156,177, or 2.0% of sales,
which was $90,901, or 139%, higher than the third quarter of 2004. Basic
earnings per share doubled to $.02 per share compared to earnings per share of
$.01 in the third quarter of 2004. Similarly, diluted earnings per share were
$.02 in the third quarter of 2005 and double the $.01 per share in the third
quarter of 2004.

      Our sales for the first nine months of 2005 were $21,238,803 and were 61%,
or $8,074,163, higher than the first nine months of 2004. In the first three
quarters of 2005, 73.5% of our sales consisted of dialysis concentrate sales,
and sales of our concentrates increased by over 45.9% in the first nine months
of 2005 compared to the first nine months of 2004. We have been successful at
developing new business over the last year with our growth attributable to unit
volume increases across the breadth of our product lines. Our growth has been
attributable to both new dialysis centers purchasing products from our core
concentrate product lines and to a substantial purchase order from a single
distributor for which we recorded revenue of $5.6 million in the first nine
months of 2005. Sales of our ancillary products grew by $3.1 million, primarily
as a result of increases in sales of specialty kits from this distributor's
purchase order.

      We have continued to realize sales growth with national and regional
dialysis chains throughout the eastern half of the United States over the last
year. In February of 2005, we announced that we had signed multiple supply
agreements with several dialysis chains and regional units of national chains in
the Southeastern United States. The aggregate annual revenue from these dialysis
chains is anticipated to be approximately $2,500,000. We began to fulfill these
supply agreements beginning in March of 2005, and we realized the full quarterly
revenue impact during the second quarter of 2005. We also opened a third
manufacturing facility in March 2005 to support the business under these supply
agreements in addition to our existing portfolio of business in the Southeastern
United States.

      We achieved accelerated growth in the Southeastern United States through
the sale of our liquid acid concentrate product lines over the last nine months.
Overall, we experienced substantial unit growth in our liquid products with the
aggregate gallons of liquid acid concentrate sold increasing by over 100% in the
first nine months of 2005 over the same period last year. The majority of the
liquid volume increase was in the Southeastern United States. We achieved a
faster and more profitable operational start-up by gaining a critical mass of
customers in a short time frame by penetrating the


                                       9


Southeast region with liquid products, which was the primary catalyst behind the
increased liquid demand. We intend to continue to attempt to convert our liquid
concentrate customers to our Dri-Sate Dry Acid Concentrate products.

      Our overall gross profit for the first nine months of 2005 increased by
$342,000, or 16.3%, while our gross profit margins decreased by 4.4 percentage
points to sales. There were both recurring and non-recurring factors that
impacted gross profit margins, including the expansion of our production
operations, transition costs as we moved order fulfillment operations between
regions, higher product delivery costs due to fuel increases and higher costs
for equipment maintenance caused by increased production volumes.

      We made an investment in the geographic expansion of our business in order
to position the Company to take advantage of new business opportunities in our
market. In March of 2005, we added a third manufacturing facility in the
Southeastern United States that increased our costs of operation. We moved
certain production, related to business in that region, to the new plant from
our other facilities, which added flexibility to our other facilities to absorb
additional volume growth. As a result, we added additional operating costs which
have not been completely offset by higher production volumes. The current
facility in the Southeast is being leased under a short term lease agreement
that is set to expire on December 10, 2005. We may release this facility or we
may relocate to another facility if we do not renew our lease at our current
facility. How a lease renewal or relocation of our facility may impact our
operating costs is not clear at this time. We anticipate that having a facility
in the Southeastern United States will enable us to realize improvements in
distribution efficiencies and will mitigate the negative impact from supplying
the Southeastern United States from our other facilities.

      Our strategy was to expeditiously penetrate the Southeastern region of the
U.S. and install a self-sustaining operation in the region in a short period of
time. We added over $5,000,000 in new annualized revenue over the last year in
that market. We have added a facility but have incurred start-up costs for
transition, above normal distribution expense to ensure continuity in product
supply and additional operating costs for the new operation. We estimate that
the transition costs including above normal operating costs were equivalent to
approximately two gross profit margin percentage points in the first nine months
of 2005. The remainder of the cost increases are the result of additional
production personnel and resources. We anticipate improvement in our overall
gross profit margins as we increase our respective plant volumes in the future.

      Selling, general and administrative expense decreased as a percentage of
sales by 3.4% to 9.9% for the first nine months of 2005 as compared to the first
nine months of 2004. Overall, selling, general and administrative expense
increased by $335,253, or 19.1%. Approximately $200,000 of the increase was for
sales and administrative personnel to handle increased transaction activity. We
also incurred approximately $35,000 in higher operating expenses for computer
infrastructure costs and over $50,000 in other operating and selling expenses
related to our substantial sales growth. In addition, we increased spending on
development of our dialysate iron product by over $55,000 from the first nine
months of last year. We have recognized $160,000 in costs related to dialysate
iron product development in the first nine months of 2005.

      Interest expense decreased by $6,582 in the first nine months of 2005
compared to the prior period, primarily due to a lower effective interest rate
under our new line of credit.

      We were the plaintiff in certain litigation that was settled in the first
quarter of 2005. We have recognized $137,468 of other income from this
settlement in 2005. A portion of the cash received was from the exercise of
stock options by the defendant during the first quarter of 2005 which totaled
$103,750.

      Net income in the first nine months of 2005 was $350,848, an improvement
of 75%, or $150,730, over the first nine months results in 2004. Basic earnings
per share for the first nine months of 2005 aggregated $.04, which was double
the basic earnings per share for the first nine months of 2004 of $.02.
Similarly, diluted earnings per share also doubled to $.04 per share in the
first nine months of 2005 as compared to $.02 for the first nine months of 2004.


                                       10


LIQUIDITY AND CAPITAL RESOURCES

     Our strategy is to expand our operations to serve dialysis providers
throughout the United States. We anticipate that, as a result of our existing
supply agreements, our customer relationships and our changing market dynamics,
we have the opportunity to capture substantial market share. We expect that we
will continue to realize substantial revenue growth and that we will require
additional working capital and capital expenditures to fund this growth. In
addition, over the next several years, we expect to make substantial investments
in our dialysate iron product in order to gain FDA approval to market dialysate
iron.

    In the first nine months of 2005, we generated cash from our business
operations and reinvested those funds into the development and expansion of our
business. We realized substantial revenue growth of over 61% in the first nine
months of 2005. Based on current and prospective developments that we anticipate
in our business in the remainder of 2005 and in 2006, we will require additional
working capital and capital expenditures to support our development plans. Our
current credit line coupled with positive cash flow from operations is expected
to provide the majority of the funding that we anticipate that we may need to
support future growth of our core concentrate and dialysis supply business.

    In addition to funding provided by operations, we intend to raise additional
capital. We continue to engage in discussions with various potential financing
sources including potential lenders, strategic partners and investors.

    In addressing our need for additional working capital, we obtained a new
line of credit with a financial institution, at the end of the first quarter of
2005, which expands our borrowing capacity. This credit line has a $2.75 million
credit limit. We are permitted to borrow up to 80% of our eligible accounts
receivable and 40% of eligible inventory up to $600,000. As of September 30,
2005, we had borrowed $1,400,000 under this line of credit.

    We are seeking FDA approval for our dialysate iron drug product. The
development and approval of drugs can be expensive and take a long time. The
development and approval costs may offset some or all of our earnings during the
approval process. We estimate the cash required to fund approval of our new iron
supplemented dialysate product will total between $5,000,000 - $7,000,000 and be
expended over the next several years. We may raise these funds ourselves or if
we do not raise the capital to fund this project ourselves, we may decide to
seek a partner with greater technical and financial resources to facilitate
approval of this product.

     On July 29, 2005, we filed with the Securities and Exchange Commission (the
"SEC") a registration statement on Forms S-4 and SB-2 (the "Registration
Statement") with respect to an offer to exchange new common share purchase
warrants expiring January 26, 2006 with an exercise price of $3.90 ("New
Warrants") for each of the 3,625,000 currently outstanding common share purchase
warrants expiring January 26, 2006 with an exercise price of $4.50 ("Old
Warrants"). The SEC declared the registration statement effective on October 20,
2005. Old Warrant holders must tender their Old Warrants by November 28, 2005 to
participate in the exchange. Both Old and New warrants expire January 26, 2006.
We would not receive any proceeds from the completion of the exchange offer,
although we would receive proceeds upon the exercise of the New Warrants. The
net proceeds to the Company from the sale of the 3,625,000 common shares
underlying the New Warrants would aggregate in excess of $13,000,000. We intend
to use the net proceeds of this offering for general working capital and may use
the proceeds: to add additional manufacturing facilities, for research and
product development and for clinical trials related to our efforts to obtain FDA
approval of our iron dialysate product and the financing of marketing and sales
activities.

     If we are not successful in raising additional funds through exercise of
warrants we may pursue other financing options. We plan to raise the capital
required to expand our operations and fund our new product development strategy
through a combination of cash flow from operations, debt or equity financing
arrangements and/or licensing arrangements; however, we may not be successful.
If we are not successful in raising additional funds, we may be required to
alter our growth strategy, defer spending on business development, curtail
production expansion plans or take other measures to conserve our cash
resources.


                                       11

    In addition, the dialysis provider market that we serve is becoming
increasingly concentrated. As a result, our business is predominantly with
national and regional dialysis chains. If we were to lose a significant portion
of our business with major national and regional dialysis chains, it could have
a substantial negative impact on our cash flow and operating results. If we were
to lose a substantial portion of our business, it may have a detrimental impact
on our ability to continue our operations in their current form or to continue
to execute our business strategy. If we lost a substantial portion of our
business, we would be required to take actions to conserve our cash resources
and to mitigate the impact of any such losses on our business operations.

ITEM 3. CONTROLS AND PROCEDURES

     We carried out an evaluation under the supervision and with the
participation of our management, including our Chief Executive Officer and Chief
Financial Officer, of the effectiveness of our disclosure controls and
procedures as of September 30, 2005. Based upon that evaluation, our Chief
Executive Officer and Chief Financial Officer concluded that our disclosure
controls and procedures are effective as of September 30, 2005 in ensuring that
information required to be disclosed by us under the Exchange Act is recorded,
processed, summarized and reported within the time periods specified under the
Exchange Act rules and forms. There was no change in our internal control over
financial reporting identified in connection with such evaluation that occurred
during our fiscal quarter ended September 30, 2005 that has materially affected,
or is reasonably likely to materially affect, our internal control over
financial reporting.

     Disclosure controls and procedures are our controls and other procedures
that are designed to ensure that information required to be disclosed by us in
the reports that we file or submit under the Exchange Act is recorded,
processed, summarized and reported, within the time periods specified in the
Securities and Exchange Commission's rules and forms. Disclosure controls and
procedures include, without limitation, controls and procedures designed to
ensure that information required to be disclosed by us in the reports that we
file or submit under the Exchange Act is accumulated and communicated to our
management, including our principal executive and principal financial officers,
as appropriate to allow timely decisions regarding required disclosure.


                                       12

     PART II - OTHER INFORMATION

ITEM 2. UNREGISTERED SALES OF EQUITY SECURITIES AND USE OF PROCEEDS

         During the third quarter of 2005, we issued 10,832 common shares upon
exercise of warrants which were issued to investors in a private placement. The
offer and sale of the above common shares upon exercise of the warrants were
exempt from the registration requirements of the Act under Section 4(2) of the
Act. We realized proceeds of $8,560, or $.79 per share on average. Warrant
holders exercising these private placement warrants received a certificate with
a restrictive legend representing the shares purchased.

ITEM 6. EXHIBITS

4.1   Warrant Agreement between Rockwell Medical Technologies, Inc. and American
      Stock Transfer & Trust Company, as Warrant Agent, incorporated by
      reference to Exhibit 4.1 on Form 8-K filed on October 20, 2005.

10.1  Second Amendment of Industrial Lease Agreement between Rockwell Medical
      Technologies, Inc. and DCT DFW, LP dated August 17, 2005, incorporated by
      reference to Exhibit 99.1 on Form 8-K filed on August 19, 2005.

31.1  Certifications of Chief Executive Officer Pursuant to Rule 13a-14(a), as
      Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

31.2  Certifications of the Chief Financial Officer Pursuant to Rule 13a-14(a),
      as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.

32.1  Certifications of the Chief Executive Officer and Chief Financial Officer,
      Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of
      the Sarbanes-Oxley Act of 2002.



                                       13

                                   SIGNATURES

In accordance with the requirements of the Exchange Act, the registrant caused
this report to be signed on its behalf by the undersigned, thereunto duly
authorized.

                                             ROCKWELL MEDICAL TECHNOLOGIES, INC.
                                                        (Registrant)


      Date: November  11, 2005               /s/ ROBERT L. CHIOINI
                                             -------------------------------
                                               Robert L. Chioini
                                             President, Chief Executive
                                             Officer and Director (Principal
                                             Executive Officer)

      Date: November  11, 2005                 /s/ THOMAS E. KLEMA
                                             -------------------------------
                                               Thomas E. Klema
                                             Vice President of Finance, Chief
                                             Financial Officer, Treasurer and
                                             Secretary (Principal Financial
                                             Officer and Principal Accounting
                                             Officer)


                                       14

                              10-QSB EXHIBIT INDEX



EXHIBIT NO.               DESCRIPTION
         
 EX-31.1    Certification of Chief Executive Officer Pursuant to Rule 13a-14(a),
            as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of
            2002.

 EX-31.2    Certification of the Chief Financial Officer Pursuant to Rule
            13a-14(a), as Adopted Pursuant to Section 302 of the Sarbanes-Oxley
            Act of 2002.

 EX-32.1    Certifications of the Chief Executive Officer and Chief Financial
            Officer, Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to
            Section 906 of the Sarbanes-Oxley Act of 2002.



                                       15