UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G

                   Under the Securities Exchange Act of 1934
                              (Amendment No. 15)*



                        PROGENICS PHARMACEUTICALS, INC.
--------------------------------------------------------------------------------
                                (Name of Issuer)



                         COMMON STOCK, par value $.0013
--------------------------------------------------------------------------------
                         (Title of Class of Securities)



                                   743187106
--------------------------------------------------------------------------------
                                 (CUSIP Number)



                               December 31, 2013
--------------------------------------------------------------------------------
            (Date of Event Which Requires Filing of this Statement)



Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

         [_] Rule 13d-1(b)

         [_] Rule 13d-1(c)

         [X] Rule 13d-1(d)

* The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 (the "Act") or otherwise subject to the liabilities of that section of the
Act but shall be subject to all other provisions of the Act (however, see the
Notes).



                                     Page 1




CUSIP No.   743187106
          -------------------

--------------------------------------------------------------------------------

     1)    Names of Reporting Person
           S.S. or I.R.S. Identification No. of Above Person

                Tudor Investment Corporation
           ---------------------------------------------------------------------
                22-2514825
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------

     2)    Check the Appropriate Box if a Member of a Group (See Instructions)
           (a)
               -----------------------------------------------------------------
           (b)    X
               -----------------------------------------------------------------
--------------------------------------------------------------------------------

     3)    SEC Use Only
                           -----------------------------------------------------
--------------------------------------------------------------------------------

     4)    Citizenship or Place of Organization    Delaware
                                                --------------------------------
--------------------------------------------------------------------------------
                   (5)   Sole Voting Power                    0
                                            ------------------------------------
Number of Shares   -------------------------------------------------------------
Beneficially       (6)   Shared Voting Power          2,342,388
Owned by Each                                 ----------------------------------
Reporting Person   -------------------------------------------------------------
With               (7)   Sole Dispositive Power               0
                                                 -------------------------------
                   -------------------------------------------------------------
                   (8)   Shared Dispositive Power     2,342,388
                                                   -----------------------------
--------------------------------------------------------------------------------
     9)    Aggregate Amount Beneficially Owned by Each Reporting
           Person                                              2,342,388
                                                           ---------------------
--------------------------------------------------------------------------------
    10)    Check if the Aggregate Amount in Row (9) Excludes Certain Shares
           (See Instructions)
                              --------------------------------------------------
--------------------------------------------------------------------------------

    11)    Percent of Class Represented by Amount in Row 9      3.8%
                                                             -------------------
--------------------------------------------------------------------------------

    12)    Type of Reporting Person (See Instructions)     CO
                                                        ------------------------
--------------------------------------------------------------------------------

                                     Page 2



CUSIP No.   743187106
          -------------------

--------------------------------------------------------------------------------

     1)    Names of Reporting Person
           S.S. or I.R.S. Identification No. of Above Person

             Tudor Group Holdings LLC
           ---------------------------------------------------------------------
             13-3862746
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------

     2)    Check the Appropriate Box if a Member of a Group (See Instructions)
           (a)
               -----------------------------------------------------------------
           (b)    X
               -----------------------------------------------------------------
--------------------------------------------------------------------------------

     3)    SEC Use Only
                           -----------------------------------------------------
--------------------------------------------------------------------------------

     4)    Citizenship or Place of Organization    Delaware
                                                --------------------------------
--------------------------------------------------------------------------------
                   (5)   Sole Voting Power                    0
                                            ------------------------------------
Number of Shares   -------------------------------------------------------------
Beneficially       (6)   Shared Voting Power                  0
Owned by Each                                 ----------------------------------
Reporting Person   -------------------------------------------------------------
With               (7)   Sole Dispositive Power               0
                                                 -------------------------------
                   -------------------------------------------------------------
                   (8)   Shared Dispositive Power             0
                                                   -----------------------------
--------------------------------------------------------------------------------
     9)    Aggregate Amount Beneficially Owned by Each Reporting
           Person                                                    0
                                                           ---------------------
--------------------------------------------------------------------------------
    10)    Check if the Aggregate Amount in Row (9) Excludes Certain Shares
           (See Instructions)
                              --------------------------------------------------
--------------------------------------------------------------------------------

    11)    Percent of Class Represented by Amount in Row 9      0%
                                                             -------------------
--------------------------------------------------------------------------------

    12)    Type of Reporting Person (See Instructions)     OO
                                                        ------------------------
--------------------------------------------------------------------------------

                                     Page 3



CUSIP No.   743187106
          -------------------

--------------------------------------------------------------------------------

     1)    Names of Reporting Person
           S.S. or I.R.S. Identification No. of Above Person

             Paul Tudor Jones, II
           ---------------------------------------------------------------------

           ---------------------------------------------------------------------
--------------------------------------------------------------------------------

     2)    Check the Appropriate Box if a Member of a Group (See Instructions)
           (a)
               -----------------------------------------------------------------
           (b)    X
               -----------------------------------------------------------------
--------------------------------------------------------------------------------

     3)    SEC Use Only
                           -----------------------------------------------------
--------------------------------------------------------------------------------

     4)    Citizenship or Place of Organization    USA
                                                --------------------------------
--------------------------------------------------------------------------------
                   (5)   Sole Voting Power              546,125
                                            ------------------------------------
Number of Shares   -------------------------------------------------------------
Beneficially       (6)   Shared Voting Power          2,342,388
Owned by Each                                 ----------------------------------
Reporting Person   -------------------------------------------------------------
With               (7)   Sole Dispositive Power         546,125
                                                 -------------------------------
                   -------------------------------------------------------------
                   (8)   Shared Dispositive Power     2,342,388
                                                   -----------------------------
--------------------------------------------------------------------------------
     9)    Aggregate Amount Beneficially Owned by Each Reporting
           Person                                              2,888,513
                                                           ---------------------
--------------------------------------------------------------------------------
    10)    Check if the Aggregate Amount in Row (9) Excludes Certain Shares
           (See Instructions)
                              --------------------------------------------------
--------------------------------------------------------------------------------

    11)    Percent of Class Represented by Amount in Row 9      4.7%
                                                             -------------------
--------------------------------------------------------------------------------

    12)    Type of Reporting Person (See Instructions)     IN
                                                        ------------------------
--------------------------------------------------------------------------------

                                     Page 4



CUSIP No.   743187106
          -------------------

--------------------------------------------------------------------------------

     1)    Names of Reporting Person
           S.S. or I.R.S. Identification No. of Above Person

                Mark F. Dalton
           ---------------------------------------------------------------------

           ---------------------------------------------------------------------
--------------------------------------------------------------------------------

     2)    Check the Appropriate Box if a Member of a Group (See Instructions)
           (a)
               -----------------------------------------------------------------
           (b)    X
               -----------------------------------------------------------------
--------------------------------------------------------------------------------

     3)    SEC Use Only
                           -----------------------------------------------------
--------------------------------------------------------------------------------

     4)    Citizenship or Place of Organization    USA
                                                --------------------------------
--------------------------------------------------------------------------------
                   (5)   Sole Voting Power              107,500
                                            ------------------------------------
Number of Shares   -------------------------------------------------------------
Beneficially       (6)   Shared Voting Power          2,342,388
Owned by Each                                 ----------------------------------
Reporting Person   -------------------------------------------------------------
With               (7)   Sole Dispositive Power         107,500
                                                 -------------------------------
                   -------------------------------------------------------------
                   (8)   Shared Dispositive Power     2,342,388
                                                   -----------------------------
--------------------------------------------------------------------------------
     9)    Aggregate Amount Beneficially Owned by Each
           Reporting Person                                    2,449,888
                                                           ---------------------
--------------------------------------------------------------------------------
    10)    Check if the Aggregate Amount in Row (9) Excludes Certain Shares
           (See Instructions)
                              --------------------------------------------------
--------------------------------------------------------------------------------

    11)    Percent of Class Represented by Amount in Row 9      4.0%
                                                             -------------------
--------------------------------------------------------------------------------

    12)    Type of Reporting Person (See Instructions)     IN
                                                        ------------------------
--------------------------------------------------------------------------------

                                     Page 5



CUSIP No.   743187106
          -------------------

--------------------------------------------------------------------------------

     1)    Names of Reporting Person
           S.S. or I.R.S. Identification No. of Above Person

             The Tudor BVI Global Portfolio L.P. (f/k/a The Tudor BVI Global
             Portfolio Ltd.)
           ---------------------------------------------------------------------
             98-0223576
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------

     2)    Check the Appropriate Box if a Member of a Group (See Instructions)
           (a)
               -----------------------------------------------------------------
           (b)    X
               -----------------------------------------------------------------
--------------------------------------------------------------------------------

     3)    SEC Use Only
                           -----------------------------------------------------
--------------------------------------------------------------------------------

     4)    Citizenship or Place of Organization      Cayman Islands
                                                --------------------------------
--------------------------------------------------------------------------------
                   (5)   Sole Voting Power                    0
                                            ------------------------------------
Number of Shares   -------------------------------------------------------------
Beneficially       (6)   Shared Voting Power          1,613,905
Owned by Each                                 ----------------------------------
Reporting Person   -------------------------------------------------------------
With               (7)   Sole Dispositive Power               0
                                                 -------------------------------
                   -------------------------------------------------------------
                   (8)   Shared Dispositive Power     1,613,905
                                                   -----------------------------
--------------------------------------------------------------------------------
     9)    Aggregate Amount Beneficially Owned by Each
           Reporting Person                                    1,613,905
                                                           ---------------------
--------------------------------------------------------------------------------
    10)    Check if the Aggregate Amount in Row (9) Excludes Certain Shares
           (See Instructions)
                              --------------------------------------------------
--------------------------------------------------------------------------------

    11)    Percent of Class Represented by Amount in Row 9      2.7%
                                                             -------------------
--------------------------------------------------------------------------------

    12)    Type of Reporting Person (See Instructions)     PN
                                                        ------------------------
--------------------------------------------------------------------------------

                                     Page 6



CUSIP No.   743187106
          -------------------

--------------------------------------------------------------------------------

     1)    Names of Reporting Person
           S.S. or I.R.S. Identification No. of Above Person

             Tudor Global Fund L.P.
           ---------------------------------------------------------------------
             98-0677065
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------

     2)    Check the Appropriate Box if a Member of a Group (See Instructions)
           (a)
               -----------------------------------------------------------------
           (b)    X
               -----------------------------------------------------------------
--------------------------------------------------------------------------------

     3)    SEC Use Only
                           -----------------------------------------------------
--------------------------------------------------------------------------------

     4)    Citizenship or Place of Organization    Cayman Islands
                                                --------------------------------
--------------------------------------------------------------------------------
                   (5)   Sole Voting Power                    0
                                            ------------------------------------
Number of Shares   -------------------------------------------------------------
Beneficially       (6)   Shared Voting Power            440,670
Owned by Each                                 ----------------------------------
Reporting Person   -------------------------------------------------------------
With               (7)   Sole Dispositive Power               0
                                                 -------------------------------
                   -------------------------------------------------------------
                   (8)   Shared Dispositive Power       440,670
                                                   -----------------------------
--------------------------------------------------------------------------------
     9)    Aggregate Amount Beneficially Owned by Each
           Reporting Person                                      440,670
                                                           ---------------------
--------------------------------------------------------------------------------
    10)    Check if the Aggregate Amount in Row (9) Excludes Certain Shares
           (See Instructions)
                              --------------------------------------------------
--------------------------------------------------------------------------------

    11)    Percent of Class Represented by Amount in Row 9       0.7%
                                                             -------------------
--------------------------------------------------------------------------------

    12)    Type of Reporting Person (See Instructions)      PN
                                                        ------------------------
--------------------------------------------------------------------------------

                                     Page 7



CUSIP No.   743187106
          -------------------

--------------------------------------------------------------------------------

     1)    Names of Reporting Person
           S.S. or I.R.S. Identification No. of Above Person

             Tudor Proprietary Trading, L.L.C.
           ---------------------------------------------------------------------
             13-3720063
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------

     2)    Check the Appropriate Box if a Member of a Group (See Instructions)
           (a)
               -----------------------------------------------------------------
           (b)    X
               -----------------------------------------------------------------
--------------------------------------------------------------------------------

     3)    SEC Use Only
                           -----------------------------------------------------
--------------------------------------------------------------------------------

     4)    Citizenship or Place of Organization    Delaware
                                                --------------------------------
--------------------------------------------------------------------------------
                   (5)   Sole Voting Power                    0
                                            ------------------------------------
Number of Shares   -------------------------------------------------------------
Beneficially       (6)   Shared Voting Power                  0
Owned by Each                                 ----------------------------------
Reporting Person   -------------------------------------------------------------
With               (7)   Sole Dispositive Power               0
                                                 -------------------------------
                   -------------------------------------------------------------
                   (8)   Shared Dispositive Power             0
                                                   -----------------------------
--------------------------------------------------------------------------------
     9)    Aggregate Amount Beneficially Owned by Each
           Reporting Person                                            0
                                                           ---------------------
--------------------------------------------------------------------------------
    10)    Check if the Aggregate Amount in Row (9) Excludes Certain Shares
           (See Instructions)
                              --------------------------------------------------
--------------------------------------------------------------------------------

    11)    Percent of Class Represented by Amount in Row 9      0%
                                                             -------------------
--------------------------------------------------------------------------------

    12)    Type of Reporting Person (See Instructions)      OO
                                                        ------------------------
--------------------------------------------------------------------------------

                                     Page 8



CUSIP No.   743187106
          -------------------

--------------------------------------------------------------------------------

     1)    Names of Reporting Person
           S.S. or I.R.S. Identification No. of Above Person

             Tudor Global Trading LLC
           ---------------------------------------------------------------------
             13-3862744
           ---------------------------------------------------------------------
--------------------------------------------------------------------------------

     2)    Check the Appropriate Box if a Member of a Group (See Instructions)
           (a)
               -----------------------------------------------------------------
           (b)    X
               -----------------------------------------------------------------
--------------------------------------------------------------------------------

     3)    SEC Use Only
                           -----------------------------------------------------
--------------------------------------------------------------------------------

     4)    Citizenship or Place of Organization     Delaware
                                                --------------------------------
--------------------------------------------------------------------------------
                   (5)   Sole Voting Power                    0
                                            ------------------------------------
Number of Shares   -------------------------------------------------------------
Beneficially       (6)   Shared Voting Power                  0
Owned by Each                                 ----------------------------------
Reporting Person   -------------------------------------------------------------
With               (7)   Sole Dispositive Power               0
                                                 -------------------------------
                   -------------------------------------------------------------
                   (8)   Shared Dispositive Power             0
                                                   -----------------------------
--------------------------------------------------------------------------------
     9)    Aggregate Amount Beneficially Owned by Each
           Reporting Person                                            0
                                                           ---------------------
--------------------------------------------------------------------------------
    10)    Check if the Aggregate Amount in Row (9) Excludes Certain Shares
           (See Instructions)
                              --------------------------------------------------
--------------------------------------------------------------------------------

    11)    Percent of Class Represented by Amount in Row 9      0%
                                                             -------------------
--------------------------------------------------------------------------------

    12)    Type of Reporting Person (See Instructions)     OO
                                                        ------------------------
--------------------------------------------------------------------------------

                                     Page 9




Item 1(a). Name of Issuer:

           Progenics Pharmaceuticals, Inc.

Item 1(b). Address of Issuer's Principal Executive Offices:

           777 Old Saw Mill River Road
           Tarrytown, NY 10591

Item 2(a). Name of Person Filing:

           Tudor Investment Corporation ("TIC")
           Tudor Group Holdings LLC ("TGH")
           Paul Tudor Jones, II
           Mark F. Dalton
           The Tudor BVI Global Portfolio L.P. ("Tudor BVI")
           Tudor Global Fund L.P. ("TGF")
           Tudor Proprietary Trading, L.L.C. ("TPT")
           Tudor Global Trading LLC ("TGT")

Item 2(b). Address of Principal Business Office or, if none, Residence:

           The principal business office of each of TIC, TGH, TPT, TGF and TGT
           is:

                          1275 King Street
                          Greenwich, CT 06831

           The principal business office of each of Messrs. Jones and Dalton is:

                          c/o Tudor Investment Corporation
                          1275 King Street
                          Greenwich, CT 06831

           The principal business office of Tudor BVI is:

                          c/o CITCO
                          Kaya Flamboyan 9
                          Curacao, Netherlands Antilles

Item 2(c). Citizenship:

           TIC is a Delaware corporation
           Tudor BVI and TGF are limited partnerships organized under the laws
           of the Cayman Islands
           Messrs. Jones and Dalton are citizens of the United States
           TGH, TPT and TGT are Delaware limited liability companies

Item 2(d). Title of Class of Securities:


                                    Page 10




           Common Stock, par value $0.0013

Item 2(e). CUSIP Number:

           743187106

Item 3.    If this statement is filed pursuant to Rules 13d-1(b), or 13d-2(b),
           check whether the person filing is a:

     (a)   [_] Broker or dealer registered under section 15 of the Act
           (15 U.S.C. 78o).

     (b)   [_] Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c).

     (c)   [_] Insurance company as defined in section 3(a)(19) of the Act (15
           U.S.C. 78c).

     (d)   [_] Investment company registered under section 8 of the Investment
           Company Act of 1940 (15 U.S.C. 80a-8).

     (e)   [_] An investment advisor in accordance with
           ss.240.13d-1(b)(1)(ii)(E).

     (f)   [_] An employee benefit plan or endowment fund in accordance with
           ss.240.13d-1(b)(1)(ii)(F).

     (g)   [_] A parent holding company or control person in accordance with
           ss.240.13d-1(b)(1)(ii)(G).

     (h)   [_] A savings association as defined in Section 3(b) of the Federal
           Deposit Insurance Act (12 U.S.C. 1813).

     (i)   [_] A church plan that is excluded from the definition of an
           investment company under Section 3(c)(14) of the Investment Company
           Act of 1940 (15 U.S.C. 80a-3).

     (j)   [_] A non-U.S. institution in accordance with ss.
           240.13d-1(b)(1)(ii)(J);

     (k)   [_] Group, in accordance with ss. 240.13d-1(b)(1)(ii)( K).

     If filing as a non-U.S. institution in accordance with ss.
240.13d-1(b)(1)(ii)(J), please specify the type of institution: _______________

Item 4.    Ownership (as of December 31, 2013).

           (a)  Amount Beneficially Owned: See Item 9 of cover pages

           (b)  Percent of Class: See Item 11 of cover pages

           (c)  Number of shares as to which such person has:

               (i)  sole power to vote or to direct the vote
                    See Item 5 of cover pages
                    -------------------------

               (ii) shared power to vote or to direct the vote
                    See Item 6 of cover pages
                    -------------------------



                                    Page 11




               (iii) sole power to dispose or to direct the disposition of
                     See Item 7 of cover pages
                     -------------------------

               (iv)  shared power to dispose or to direct the disposition of
                     See Item 8 of cover pages
                     -------------------------
                     -----------------------------------------------------------

      The shares of common stock ("Shares") reported herein as beneficially
owned by TIC, TGH, Mr. Jones and/or Mr. Dalton include shares owned directly by
Tudor BVI (1,613,905 Shares), and/or TGF (440,670 Shares).

      Because TIC provides investment advisory services to each of Tudor BVI and
TGF and acts as general partner of TGF, TIC may be deemed to beneficially own
the Shares owned by Tudor BVI and TGF. TIC expressly disclaims beneficial
ownership of such Shares. TGH holds a majority of the equity interests of TGT
and indirectly holds a majority of the membership interests of TPT. TGH
expressly disclaims beneficial ownership of the Shares beneficially owned by
each of such entities. Mr. Jones is the Co-Chairman and principal equity owner
of TIC and TGH. Mr. Jones expressly disclaims beneficial ownership of the Shares
beneficially owned, or deemed beneficially owned, by such entities. Mr. Dalton
is (i) the Co-Chairman, Chief Executive Officer, and an equity owner of TIC and
(ii) the Co-Chairman, Chief Executive Officer, and an equity owner of TGH. Mr.
Dalton expressly disclaims beneficial ownership of the Shares beneficially
owned, or deemed beneficially owned, by such entities.

      The Shares reported herein under Items 5 and 7 of Mr. Jones' cover page
include 4,600 Shares held directly by Mr. Jones' individual retirement account.

      The Shares reported herein under Items 5 and 7 of Mr. Dalton's cover page
include 70,000 immediately exercisable options (the "Options"). Further, the
Shares reported herein under Items 5 and 7 of Mr. Dalton's cover page include
37,500 of the Shares.

Item 5.    Ownership of Five Percent or Less of a Class.

      If this statement is being filed to report that as of the date hereof the
reporting person has ceased to be the beneficial owner of more than five percent
of the class of securities, check the following [X].

Item 6.    Ownership of More than Five Percent on Behalf of Another Person.

              Not applicable

Item 7.    Identification and Classification of the Subsidiary Which Acquired
           the Security Being Reported on By the Parents Holding Company.

              Not applicable

Item 8.    Identification and Classification of Members of the Group.

              See cover pages

Item 9.    Notice of Dissolution of Group.

              Not applicable

Item 10.   Certification.


                                    Page 12




          By signing below I certify that, to the best of my knowledge and
belief, the securities referred to above were acquired and are held in the
ordinary course of business and were not acquired and are not held for the
purpose of or with the effect of changing or influencing the control of the
issuer of the securities and were not acquired and are not held in connection
with or as a participant in any transaction having that purpose or effect.










                                    Page 13





          After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.


                                           Dated: February 14, 2014

                                           TUDOR INVESTMENT CORPORATION


                                           By:     /s/ Stephen N. Waldman
                                              ----------------------------------
                                              Stephen N. Waldman
                                              Managing Director and Deputy
                                                General Counsel

                                           TUDOR GROUP HOLDINGS LLC


                                           By:     /s/ Stephen N. Waldman
                                              ----------------------------------
                                              Stephen N. Waldman
                                              Managing Director and Deputy
                                                General Counsel



                                                  /s/ Paul Tudor Jones, II
                                              ----------------------------------
                                                  Paul Tudor Jones, II



                                                  /s/ Mark F. Dalton
                                              ----------------------------------
                                                  Mark F. Dalton


                                           THE TUDOR BVI GLOBAL PORTFOLIO L.P.

                                           By:    Tudor BVI GP Ltd.
                                           Its:   General Partner

                                           By:    Tudor Investment Corporation,
                                                  Trading Advisor

                                           By:     /s/ Stephen N. Waldman
                                              ----------------------------------
                                              Stephen N. Waldman
                                              Managing Director and Deputy
                                                General Counsel







                                           TUDOR GLOBAL FUND L.P.

                                           By:    Tudor Investment Corporation,
                                           Its:   General Partner

                                           By:       /s/ Stephen N. Waldman
                                              ----------------------------------
                                              Stephen N. Waldman
                                              Managing Director and Deputy
                                                General Counsel

                                           TUDOR PROPRIETARY TRADING, L.L.C.


                                           By:      /s/ Stephen N. Waldman
                                              ----------------------------------
                                              Stephen N. Waldman
                                              Managing Director and Deputy
                                                General Counsel

                                           TUDOR GLOBAL TRADING LLC


                                           By:      /s/ Stephen N. Waldman
                                              ----------------------------------
                                              Stephen N. Waldman
                                              Managing Director and Deputy
                                                General Counsel