UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549

                                  SCHEDULE 13G

                    Under the Securities Exchange Act of 1934
                               (Amendment No. 4 )*

                                   AKORN, INC.
                                (Name of Issuer)

                           Common Stock, no par value
                         (Title of Class of Securities)

                                    009728106
                                 (CUSIP Number)

                                December 31, 2005
                      (Date of Event which Requires Filing
                               of this Statement)

Check the  appropriate box to designate the rule pursuant to which this Schedule
is filed:

                                [X] Rule 13d-1(b)
                                [ ] Rule 13d-1(c)
                                [ ] Rule 13d-1(d)


*The  remainder of this cover page shall be filled out for a reporting  person's
initial filing on this form with respect to the subject class of securities, and
for any  subsequent  amendment  containing  information  which  would  alter the
disclosures provided in a prior cover page.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the  Securities  Exchange  Act of
1934 ("Act") or otherwise  subject to the liabilities of that section of the Act
but  shall be  subject  to all other  provisions  of the Act  (however,  see the
Notes).

                          Continued on following pages
                                Page 1 of 5 Pages



                                                               Page 2 of 5 Pages
1     Names of Reporting Persons
      I.R.S. Identification Nos. of above persons (entities only)

               PEQUOT CAPITAL MANAGEMENT, INC.
               06-1524885

2     Check the Appropriate Box If a Member of a Group (See Instructions)
                                     a. [ ]
                                     b. [ ]

3     SEC Use Only

4     Citizenship or Place of Organization

               CONNECTICUT

                    5     Sole Voting Power
 Number of                     18,209,878
  Shares
Beneficially        6     Shared Voting Power
 Owned By                      0
  Each
Reporting           7     Sole Dispositive Power
 Person                        18,373,972
  With
                    8     Shared Dispositive Power
                               0

9     Aggregate Amount Beneficially Owned by Each Reporting Person

                    18,373,972

10    Check Box If the Aggregate Amount in Row (9) Excludes Certain
      Shares (See Instructions)

                    [   ]

11    Percent of Class Represented By Amount in Row (9)

                    42.7%

12    Type of Reporting Person (See Instructions)

                    IA, CO





                                                               Page 3 of 5 Pages

Item 1(a)  Name of Issuer:

           Akorn, Inc.(the "Issuer").

Item 1(b)  Address of the Issuer's Principal Executive Offices:

           2500 Millbrook Drive Buffalo Grove, IL 60089

Item 2(a)  Name of Person Filing:

           This statement is filed on behalf of Pequot Capital Management,  Inc.
           (the "Reporting Person").

Item 2(b)  Address of Principal Business Office or, if None, Residence:

           The address of the principal  business office of the Reporting Person
           is 500 Nyala Farm Road, Westport, CT, 06880.

Item 2(c)  Citizenship:

           Pequot Capital Management, Inc. is a Connecticut corporation.

Item 2(d)  Title of Class of Securities:

           Common Stock, no par value per share (the "Common Stock").

Item 2(e)  CUSIP Number:

           009728106

Item  3.   This statement is filed pursuant to Rule 13d-1(b)(1)(ii)(E).

           The  Reporting  Person  is an  investment  adviser  registered  under
           Section 203 of the Investment Advisers Act of 1940.


Item 4.    Ownership:

           Ownership as of December 31, 2005 is incorporated herein by reference
           from  items  (5) - (9) and (11) of the  cover  page of the  Reporting
           Person.

           The Reporting  Person is an investment  adviser  registered under the
           Investment  Advisers Act of 1940,  and acts as investment  adviser to
           certain managed  accounts over which the Reporting  Person  exercises
           discretionary  authority  (the  "Accounts").   The  Reporting  Person
           beneficially owns 18,373,972 shares of Common Stock of Issuer, due to
           the beneficial  ownership of the following:  (i) 2,996,000  shares of
           Common  Stock;  (ii)  12,184,145  shares of Common  Stock  underlying
           80,000 shares of the Issuer's Series A 6%  Participating  Convertible
           Preferred  Stock,  par value $1.00 per share and 2,007,604  shares of
           Common Stock  underlying  50,000  shares of the Issuer's  Series B 6%
           Participating  Convertible Preferred Stock, par value $1.00 per share
           (the "Preferred Stock"), as of the date hereof, subject to adjustment
           from  time-to-time and in accordance with the terms and conditions of
           the Issuer's Articles of Amendment to Articles of Incorporation;  and
           (iii) 630,667 shares of Common Stock  underlying  warrants for Common



           Stock,  at a purchase  price of $1.00 per share and 555,556 shares of
           Common  Stock  underlying  warrants for Common  Stock,  at a purchase
           price of $3.50 per share (collectively,  the "Warrants"),  subject to
           adjustment from  time-to-time as provided in such Warrants and in the
           Warrant Agreements between the Issuer and the Reporting Person, dated
           October 7, 2003 and August 23, 2004, respectively.


Item 5.    Ownership of Five Percent or Less of a Class:

           This Item 5 is not applicable.

Item 6.    Ownership of More than Five Percent on Behalf of Another Person:

           The  reporting  person  is an  investment  adviser  registered  under
           Section 203 of the Investment  Advisers Act of 1940 and, as such, has
           beneficial  ownership  of the  shares  which are the  subject of this
           filing  through  the  investment   discretion  the  reporting  person
           exercises over its clients'  accounts.  Although such accounts do not
           have  beneficial  ownership of such shares for purposes of Section 13
           and Section 16 of the  Securities  Exchange Act of 1934, two accounts
           of the reporting  person,  Pequot  Healthcare  Fund,  L.P. and Pequot
           Healthcare  Offshore Fund,  Inc.,  each own of record more than 5% of
           the issuer's outstanding shares.

Item 7.    Identification and Classification of the Subsidiary Which Acquired
           the Security Being Reported on by the Parent Holding Company:

           This Item 7 is not applicable.

Item 8.    Identification and Classification of Members of the Group:

           This Item 8 is not applicable.

Item 9.    Notice of Dissolution of Group:

           This Item 9 is not applicable.

Item 10.   Certification:

           By signing below each of the Reporting Persons certifies that, to the
best of such person's  knowledge and belief,  the  securities  referred to above
were  acquired  and are held in the  ordinary  course of  business  and were not
acquired  and are not held for the  purpose of or with the effect of changing or
influencing  the control of the Issuer of such  securities and were not acquired
and are not  held in  connection  with or as a  participant  in any  transaction
having such purpose or effect.




                                   SIGNATURES


           After reasonable  inquiry and to the best of my knowledge and belief,
the  undersigned  certifies that the  information set forth in this statement is
true, complete and correct.

Date:  February 10, 2006               PEQUOT CAPITAL MANAGEMENT, INC.

                                       By:      /s/ Aryeh Davis
                                               ---------------------------------
                                       Name:    Aryeh Davis
                                       Title:   Chief Operating Officer,
                                                General Counsel and Secretary