Form N-Q

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, DC 20549

FORM N-Q


QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED MANAGEMENT INVESTMENT COMPANY

Investment Company Act file number         811-21471         

        Nuveen Tax-Advantaged Total Return Strategy Fund         
(Exact name of registrant as specified in charter)


        333 West Wacker Drive, Chicago, Illinois 60606         

(Address of principal executive offices) (Zip code)


Jessica R. Droeger—Vice President and Secretary
        333 West Wacker Drive, Chicago, Illinois 60606         

(Name and address of agent for service)

Registrant's telephone number, including area code:         312-917-7700        

Date of fiscal year end:            12/31          

Date of reporting period:          09/30/05         

Form N-Q is to be used by management investment companies, other than small business investment companies registered on Form N-5 (§§ 239.24 and 274.5 of this chapter), to file reports with the Commission, not later than 60 days after the close of the first and third fiscal quarters, pursuant to rule 30b1-5 under the Investment Company Act of 1940 (17 CFR 270.30b1-5). The Commission may use the information provided on Form N-Q in its regulatory, disclosure review, inspection, and policymaking roles.

A registrant is required to disclose the information specified by Form N-Q, and the Commission will make this information public. A registrant is not required to respond to the collection of information contained in Form N-Q unless the Form displays a currently valid Office of Management and Budget (“OMB”) control number. Please direct comments concerning the accuracy of the information collection burden estimate and any suggestions for reducing the burden to the Secretary, Securities and Exchange Commission, 450 Fifth Street, NW, Washington, DC 20549-0609. The OMB has reviewed this collection of information under the clearance requirements of 44 U.S.C. § 3507.

Item 1. Schedule of Investments

  Nuveen Tax-Advantaged Total Return Strategy Fund (JTA)
Portfolio of Investments (Unaudited)
September 30, 2005

  Shares    Description(1)           Value 
 
      COMMON STOCKS - 98.0% (69.1% of Total Investments)             
      Aerospace & Defense - 5.7%             
  140,000    Lockheed Martin Corporation          $   8,545,600 
  235,000    Raytheon Company            8,934,700 
 
 
                  17,480,300 
 
      Commercial Banks - 4.6%             
  150,000    Wachovia Corporation            7,138,500 
  120,000    Wells Fargo & Company            7,028,400 
 
                  14,166,900 
 
      Commercial Services & Supplies - 3.9%             
  285,000    Pitney Bowes Inc.            11,895,900 
 
      Containers & Packaging - 1.9%             
  300,000    Packaging Corp of America            5,823,000 
 
      Diversified Financial Services - 6.3%             
  275,000    Citigroup Inc.            12,518,000 
  205,000    JPMorgan Chase & Co.            6,955,650 
 
                  19,473,650 
 
      Diversified Telecommunication Services - 12.1%             
  343,000    KT Corporation, Sponsored ADR            7,717,500 
  385,000    SBC Communications Inc.            9,228,450 
  330,000    Sprint Corporation            7,847,400 
  235,000    Telecom Italia S.p.A., Sponsored ADR            6,490,700 
  190,000    Verizon Communications Inc.            6,211,100 
 
                  37,495,150 
 
      Electric Utilities - 4.2%             
  254,000    EDP - Energias de Portugal, S.A.Sponsored ADR            7,086,600 
  323,000    Korea Electric Power Corporation (KEPCO), Sponsored ADR            5,720,330 
 
                  12,806,930 
 
      Food & Staples Retailing - 3.1%             
  181,500    Albertson's, Inc.            4,655,475 
  240,625    J. Sainsbury plc, Sponsored ADR            4,752,344 
 
                  9,407,819 
 
      Household Durables - 2.3%             
  307,000    Newell Rubbermaid Inc.            6,953,550 
 
      Household Products - 3.1%             
  160,000    Kimberly-Clark Corporation            9,524,800 
 
      Insurance - 5.4%             
  330,000    Aon Corporation            10,586,400 
  80,000    Hartford Financial Services Group, Inc.            6,173,600 
                      16,760,000 
 
      Metals & Mining - 7.9%                 
  404,000    Alumina Limited, Sponsored ADR                7,631,560 
  90,000    POSCO, ADR                5,090,400 
  71,000    Rio Tinto plc, Sponsored ADR                11,665,300 
 
                      24,387,260 
 
 
      Multi-Utilities & Unregulated Power - 4.4%                 
  110,000    Dominion Resources Inc.                9,475,400 
  180,000    United Utilities plc, Sponsored ADR                4,217,400 
 
                      13,692,800 
 
      Oil, Gas, & Consumable Fuels - 10.5%                 
  80,000    ChevronTexaco Corporation                5,178,400 
  113,400    ConocoPhillips                7,927,794 
  53,000    Eni S.p.A., Sponsored ADR                7,849,300 
  39,669    Kerr-McGee Corporation                3,852,257 
  55,000    Total SA, Sponsored ADR                7,470,100 
 
                      32,277,851 
 
      Paper & Forest Products - 2.1%                 
  220,000    International Paper Company                6,556,000 
 
      Pharmaceuticals - 2.0%                 
  230,000    Merck & Co. Inc.                6,258,300 
 
      Road & Rail - 2.1%                 
  90,000    Union Pacific Corporation                6,453,000 
 
      Thrifts & Mortgage Finance - 6.5%                 
  212,000    Fannie Mae                9,501,840 
  265,000    IndyMac Bancorp, Inc.                10,488,700 
 
                      19,990,540 
 
      Tobacco - 9.9%                 
  235,000    Altria Group, Inc.                17,321,850 
  330,000    Loews Corp - Carolina Group                13,077,900 
 
                      30,399,750 
 
      Total Common Stocks (cost $263,728,132)                301,803,500 
 
                     
  Ratings** 
   
  Shares    Description(1)    Coupon     Moody's    S&P    Value 
 
      PREFERRED SECURITIES - 12.2% (8.6% of Total Investments)                 
      Capital Markets - 1.3%                 
  15,500    Bear Stearns Companies, Series E    6.150 %    A3    BBB    794,375 
  25,000    Goldman Sachs Group Inc.    4.510 %    A2    A-    633,750 
  77,700    Lehman Brothers Holdings Inc., Series F    6.500 %    A3    A-    2,042,733 
  25,000    Merrill Lynch & Company    4.610 %    A2    A-    628,750 
 
                      4,099,608 
 
      Commercial Banks - 2.2%                 
  41,100    Abbey National plc, Series C    7.375 %      A2    A-    1,071,066 
  23,500    Abbey National plc, Series B    7.375 %    A2    A    627,450 
  40,000    ABN AMRO Capital Trust Fund VII    6.080 %    A2    A    997,200 
  25,000    Banco Santander    6.410 %    A2    BBB+    645,000 
  40,000    HSBC USA Inc.    4.804 %      A2    A-    1,015,200 
  40,000    Royal Bank of Scotland Group plc, Series M    6.400 %      A1    A    1,019,200 
  40,000    Royal Bank of Scotland Group plc, Series N    6.350 %      A1    A    1,016,400 

 
                        6,391,516 

      Consumer Finance - 1.0%                   
  45,000    HSBC Finance Corporation    6.360 %      A3    BBB+    1,138,050 
  36,100    SLM Corporation, Series A    6.970 %      Baa1    BBB+    1,956,620 

                        3,094,670 

      Diversified Financial Services - 1.5%                   
  10,000    CIT Group Inc., Series A    6.350 %      Baa1    BBB+    253,700 
  19,500    Citigroup Inc., Series F    6.365 %      Aa3    A    1,004,250 
  28,900    Citigroup Inc., Series H    6.231 %      Aa3    A    1,510,025 
  5,000    ING Group NV    7.050 %      N/R    A    129,500 
  48,400    ING Group NV    7.200 %      A2    A    1,263,724 
  23,800    ING Group NV    6.200 %      A2    A    599,046 

                        4,760,245 

      Electric Utilities - 2.2%                   
  39,500    Alabama Power Company, Series A    5.300 %      Baa1    BBB+    958,665 
  12,400    Consolidated Edison Company of New York, Inc.    5.000 %      A3    BBB+    1,122,200 
  41,500    Interstate Power and Light Company    7.100 %      Baa3    BBB-    1,130,875 
  40,000    Mississippi Power Company    5.250 %      A3    BBB+    963,000 
  40,000    Savannah Electric & Power Company    6.000 %      Baa1    BBB+    1,056,000 
  5,000    Southern California Edison Company    6.125 %      Baa3    BBB-    502,813 
  9,000    Southern California Edison Company, Series A    5.349 %      Baa3    BBB-    919,688 

                        6,653,241 

      Insurance - 1.9%                   
  50,300    Ace Ltd., Series C    7.800 %      Baa2    BBB-    1,325,405 
  40,000    Aegon NV    6.375 %      A3    A-    1,019,600 
  40,000    Genworth Financial Inc., Series A    5.250 %      Baa1    BBB+    2,081,252 
  30,000    Prudential plc    6.750 %      Baa1    A    772,200 
  30,000    Prudential plc    6.500 %      Baa1    A    754,500 

                        5,952,957 

      Thrifts & Mortgage Finance - 2.1%                   
  20,000    Fannie Mae    5.500 %      Aa3    AA-    930,000 
  24,300    Fannie Mae    5.125 %      Aa3    AA-    1,029,105 
  35,000    Fannie Mae    5.810 %      Aa3    AA-    1,697,500 
  20,000    Federal Home Loan Mortgage Corporation    5.700 %      Aa3    AA-    963,000 
  18,400    Federal Home Loan Mortgage Corporation    6.000 %      Aa3    AA-    927,360 
  21,900    Federal Home Loan Mortgage Corporation    5.000 %      Aa3    AA-    930,750 

                        6,477,715 

      Total Preferred Securities (cost $37,743,769)                  37,429,952 

                       
Ratings** 
    Principal           Stated
  Amount (000)    Description(1)    Coupon   Maturity    Moody's    S&P    Value 

      CORPORATE BONDS - 3.4% (2.4% of Total Investments)                   
      Hotels Restaurants & Leisure - 1.4%                   
$   2,000    MGM Mirage    6.750 %         8/01/07    Ba1    BB+    2,045,000 
  2,000    Park Place Entertainment    8.875 %  9/15/08    Ba2    BB-    2,192,500 

                        4,237,500 

      Household Durables - 1.3%                   
  2,000    D.R. Horton, Inc.    7.500 %  12/01/07    Ba1    BB+    2,103,084 
  2,000    Standard Pacific Corporation    6.500 %  10/01/08    Ba2    BB    1,992,500 
                        4,095,584 
 
      Paper & Forest Products - 0.7%                   
  2,000    Georgia-Pacific Corp    7.375 %  7/15/08    Ba2    BB+    2,105,000 
 
      Total Corporate Bonds (cost $10,531,607)                  10,438,084 
 
                             
                         
  Ratings** 
  Principal Amount (000) Weighted Average Coupon Stated 
Maturity*



  Description(1)       Moody's   S&P   Value
 
      VARIABLE RATE SENIOR LOAN INTERESTS(2) - 21.2% (15.0% of Total Investments)                   
      Aerospace & Defense - 1.8%                   
  1,644    Hexcel, Term Loan B    5.313 %  3/01/12    B2    B+    1,663,629 
  1,900    K & F Industries, Inc., Term Loan B    6.284 %  11/18/12    B2    B+    1,914,250 
  1,625    Vought Aircraft Industries, Inc., Term Loan    6.350 %  12/22/11    Ba3    B+    1,643,701 
  364    Vought Aircraft Industries, Inc., Tranche B, Letter of Credit    5.840 %  12/22/10    Ba3    B+    368,239 
 
                        5,589,819 
 
      Auto Components - 0.6%                   
  2,000    Federal-Mogul Corporation, Term Loan A (a)    6.090 %  2/24/04    N/R    N/R    1,880,000 
 
      Building Products - 0.6%                   
  1,774    PP Holding Corporation, Term Loan    6.100 %  11/12/11    B1    B    1,779,992 
 
      Chemicals - 0.7%                   
  1,990    Rockwood Specialties Group, Inc., Tranche D    5.930 %  7/30/12    B1    B+    2,024,203 
 
      Commercial Services & Supplies - 0.8%                   
  703    Allied Waste North America, Inc., Letter of Credit    3.100 %  3/21/12    B1    BB    708,851 
  1,841    Allied Waste North America, Inc., Term Loan B    5.851 %  3/12/21    B1    BB    1,856,936 
 
                        2,565,787 
 
      Containers & Packaging - 0.9%                   
  788    Owens-Illinois Group, Inc., Term Loan B    5.570 %  4/01/08    B1    N/R    797,791 
  175    Smurfit-Stone Container Corporation, Deposit-Funded Commitment    2.100 %  11/01/11    Ba3    BB-    176,607 
  1,389    Smurfit-Stone Container Corporation, Term Loan B    5.697 %  11/01/11    Ba3    BB-    1,404,349 
  427    Smurfit-Stone Container Corporation, Term Loan C    5.834 %  11/01/11    Ba3    BB-    432,107 
 
                        2,810,854 
 
      Diversified Telecommunication Services - 0.7%                   
  2,000    Madison River Term Loan    6.220 %  9/29/08    B1    B+    2,033,750 
 
      Electrical Equipment - 0.6%                   
  1,630    Sensus Metering Systems Inc., Term Loan B-1    5.954 %  7/29/12    B2    B+    1,649,796 
  254    Sensus Metering Systems Inc., Term Loan B-2    5.969 %  12/17/10    B2    B+    257,368 
 
                        1,907,164 
 
      Health Care Providers & Services - 1.6%                   
  972    Alderwoods Group, Inc., Term Loan B-2    5.748 %  12/17/10    B1    BB-    986,658 
  2,000    Davita Inc., Term Loan B (b)    TBD   TBD    B1    BB-    2,032,084 
  1,975    IASIS Healthcare LLC, Term Loan B    5.770 %  6/22/11    B1    B+    2,006,036 
 
                        5,024,778 
 
      Hotels Restaurants & Leisure - 3.0%                   
  2,000    24 Hour Fitness Worldwide, Inc., Term Loan B    6.780 %  6/06/05    B2    B    2,033,750 
  1,970    Jack in the Box, Inc., Term Loan    5.446 %  1/09/10    Ba2    BB    1,990,931 
  2,000    Penn National Gaming, Inc., Term Loan B (b)    TBD   TBD    Ba3    BB-    2,027,656 
  1,400    Pinnacle Entertainment, Term Loan B (b)    TBD   TBD    B1    BB-    1,412,688 
  342    Venetian Casino Resort, LLC, Delayed Draw, Term Loan (c)    5.770 %  6/15/11    B1    BB-    345,272  
  1,658    Venetian Casino Resort, LLC, Term Loan    5.770 %  6/15/11    B1    BB-    1,674,572  

                        9,484,869  

      Household Durables - 0.5%                   
  1,470    Sealy Mattress Company, Term Loan D    5.572 %  4/06/12    B1    B+    1,487,800  

      Household Products - 1.0%                   
  2,955    Solo Cup Company, Term Loan    5.938 %  2/27/11    B1    B+    2,967,189  

      Insurance - 0.4%                   
  1,100    Conseco, Inc., Term Loan    5.768 %  6/22/10    B2    BB-    1,114,094  

      IT Services - 1.2%                   
  1,765    Fidelity National Information Services, Term Loan B    5.478 %  3/09/13    Ba3    BB    1,773,510  
  2,000    SunGard Data System, Term Loan B    6.280 %  1/25/13    B1    B+    2,025,228  

                        3,798,738  

      Machinery - 0.4%                   
  1,099    Dresser-Rand Group Inc., Term Loan    6.047 %  10/10/10    B1    B+    1,118,453  

      Media - 3.2%                   
  1,973    Charter Communications Operating, LLC, Term Loan B    6.930 %  4/07/11    B2    B    1,984,218  
  1,985    Emmis Operating Company, Term Loan    5.518 %  11/10/11    Ba2    B+    2,001,624  
  2,000    Metro-Goldwyn Mayer Studios, Inc., Term Loan B    6.270 %  4/12/12    N/R    N/R    2,026,250  
  1,910    Regal Cinemas Corporation, Term Loan    6.020 %  11/10/10    Ba3    BB-    1,932,240  
  2,213    WMG Acquisition Corp., Term Loan    5.700 %  2/27/11    B1    B+    2,240,693  

                        10,185,025  

      Metals & Mining - 0.9%                   
  2,723    Amsted Industries Incorporated, Term Loan B    6.198 %  10/15/10    B1    BB-    2,773,060  

      Real Estate - 1.6%                   
  784    Crescent Real Estate Funding XII, L.P., Term Loan    5.943 %  3/20/06    N/R    N/R    788,320  
  1,987    General Growth Properties, Inc., Term Loan B    5.850 %  11/12/08    Ba2    BB+    2,014,339  
  1,960    LNR Property Corporation, Term Loan    6.711 %  2/03/08    B2    B+    1,985,664  

                        4,788,323  

      Trading Companies & Distributors - 0.7%                   
  2,000    United Rentals, Term Loan B (b)    TBD   TBD    BB    B2    2,019,750  

      Total Variable Rate Senior Loan Interests (cost $64,757,630)                  65,353,648  

      REPURCHASE AGREEMENTS - 7.0% (4.9% of Total Investments)                   
 
$   21,537    State Street Bank, 3.150%, dated 9/30/05, due 10/03/05, repurchase price $21,542,436,
collateralized by $21,970,000, U.S. Treasury
Bonds, 3.875%, due 5/15/10, value $21,970,000  
                21,536,783  
                     



      Total Repurchase Agreements (cost $21,536,783)                  21,536,783  

      Total Investments (cost $398,297,921) - 141.8%                  436,561,967  

      FundNotes - (25.3)%                  (78,000,000 ) 

      Other Assets Less Liabilities - (1.9)%                  (5,676,151 ) 

      FundPreferred Shares, at Liquidation Value - (14.6)%                  (45,000,000 ) 

      Net Assets Applicable to Common Shares - 100%              $    307,885,816  







(1 )    All percentages shown in the Portfolio of Investments are based on net assets applicable to Common shares 
    unless otherwise noted. 
(2 )    Senior Loans in which the Fund invests generally pay interest at rates which are periodically adjusted by 
    reference to a base short-term, floating lending rate plus an assigned fixed rate. These floating lending rates 
    are generally (i) the lending rate referenced by the London Inter-Bank Offered Rate ("LIBOR"), or (ii) the prime 
    rate offered by one or more major United States banks. 
    Senior loans may be considered restricted in that the Fund ordinarily is contractually obligated to receive 
    approval from the Agent Bank and/or Borrower prior to the disposition of a Senior Loan. 
*     Senior Loans in the Fund’s portfolio generally are subject to mandatory and/or optional prepayment. 
    Because of these mandatory prepayment conditions and because there may be significant economic incentives 
    for a Borrower to prepay, prepayments of Senior Loans in the Fund’s portfolio may occur. As a result, the 
    actual remaining maturity of Senior Loans held in the Fund’s portfolio may be substantially less than the stated 
    maturities shown. 
**     Ratings below Baa by Moody’s Investor Service, Inc. or BBB by Standard & Poor’s Group are considered to 
    be below investment grade. 
(a)     At or subsequent to September 30, 2005, this issue was under the protection of Federal Bankruptcy Court. 
(b)     Purchased on a when-issued or delayed delivery basis. 
ADR     American Depository Receipt 
TBD     Senior Loan purchased on a when-issued basis in the primary market. Certain details associated with 
    this purchase are not known prior to the settlement date of the transaction. In addition, Senior Loans typically 
    trade without accrued interest and therefore a weighted average coupon rate is not available prior to settlement. 
    At settlement, if still unknown, the borrower or counterparty will provide the Fund with the final weighted 
    average coupon rate and maturity date. 
N/R     Investment is not rated. 

Income Tax Information

The following information is presented on an income tax basis. Differences between amounts for financial statement and federal income tax purposes are primarily due to timing differences in recognizing market discount, amortization on premium and timing differences in recognizing certain gains and losses on investment transactions.

At September 30, 2005, the cost of investments was $398,605,414.

Gross unrealized appreciation and gross unrealized depreciation of investments at September 30, 2005, were as follows:







Gross unrealized:       
   Appreciation    $   51,453,411  
   Depreciation      (13,496,858 ) 

Net unrealized appreciation of investments    $   37,956,553  








Item 2. Controls and Procedures.

  1. The registrant's principal executive and principal financial officers, or persons performing similar functions, have concluded that the registrant's disclosure controls and procedures (as defined in Rule 30a-3(c) under the Investment Company Act of 1940, as amended (the "1940 Act") (17 CFR 270.30a-3(c))) are effective, as of a date within 90 days of the filing date of this report that includes the disclosure required by this paragraph, based on their evaluation of the controls and procedures required by Rule 30a-3(b) under the 1940 Act (17 CFR 270.30a-3(b)) and Rule 13a-15(b) or 15d-15(b) under the Securities Exchange Act of 1934 (17 CFR 240.13a-15(b) or 240.15d-15(b)).
  2. There were no changes in the registrant's internal control over financial reporting (as defined in Rule 30a-3(d) under the 1940 Act (17 CFR 270.30a-3(d)) that occurred during the registrant's last fiscal quarter that have materially affected, or are reasonably likely to materially affect, the registrant's internal control over financial reporting.

Item 3. Exhibits.

File as exhibits as part of this Form a separate certification for each principal executive officer and principal financial officer of the registrant as required by Rule 30a-2(a) under the 1940 Act (17 CFR 270.30a-2(a)), exactly as set forth below: EX-99 CERT Attached hereto.


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

(Registrant)         Nuveen Tax-Advantaged Total Return Strategy Fund        

By (Signature and Title)*          /s/ Jessica R. Droeger                     
                                                    Jessica R. Droeger
                                                    Vice President and Secretary

Date         11/29/05        

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By (Signature and Title)*         /s/ Gifford R. Zimmerman                    
                                                   Gifford R. Zimmerman
                                                   Chief Administrative Officer (principal executive officer) 

Date         11/29/05        

By (Signature and Title)*         /s/ Stephen D. Foy                              
                                                   Stephen D. Foy
                                                   Vice President and Controller (principal financial officer) 

Date         11/29/05        

* Print the name and title of each signing officer under his or her signature.