Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
Hippel James
   2. Issuer Name and Ticker or Trading Symbol
BIO-TECHNE Corp [TECH] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
Chief Financial Officer
(Last)
(First)
(Middle)
614 MCKINLEY PLACE N.E.		 3. Date of Earliest Transaction (Month/Day/Year)
05/01/2019
(Street)

MINNEAPOLIS, MN 55413		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 05/01/2019   M   35,000 A $ 86.25 39,382 D  
Common Stock 05/01/2019   S   35,000 D $ 203.0766 (1) 4,382 D  

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Options (Right to buy) $ 86.25 05/01/2019   M   10,000   06/30/2015 04/01/2021 Common Stock 10,000 $ 0 0 D  
Stock Options (Right to buy) $ 86.25 05/01/2019   M   25,000   04/01/2018 04/01/2021 Common Stock 25,000 $ 0 0 D  
Restricted Stock Units (2)               (3)   (3) Common Stock 3,383   3,383 D  
Restricted Stock Units (2)               (4)   (4) Common Stock 4,438   4,438 D  
Restricted Stock Units (2)               (5)   (5) Common Stock 4,925   4,925 D  
Stock Option (Right to Buy) $ 106.59               (6) 08/18/2023 Common Stock 30,400   30,400 D  
Stock Option (Right to Buy) $ 94.35               (7) 08/12/2021 Common Stock 35,000   35,000 D  
Stock Options (Right to buy) $ 177.32               (8) 08/08/2025 Common Stock 24,089   24,089 D  
Stock Options (Right to buy) $ 177.32               (3) 08/08/2025 Common Stock 18,066   18,066 D  
Stock Options (Right to buy) $ 125.05               (4) 08/09/2024 Common Stock 24,460   24,460 D  
Stock Options (Right to buy) $ 125.05               (9) 08/09/2024 Common Stock 32,613   32,613 D  
Stock Options (Right to buy) $ 108.49               (10) 08/07/2022 Common Stock 25,000   25,000 D  
Stock Options (Right to buy) $ 106.59               (11) 08/18/2023 Common Stock 40,533   40,533 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
Hippel James
614 MCKINLEY PLACE N.E.
MINNEAPOLIS, MN 55413		       Chief Financial Officer  

Signatures

 /s/ Brenda S. Furlow, attorney in fact for James Hippel pursuant to Power of Attorney previously filed   05/02/2019
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $201.28 to $205.38, inclusive. The reporting person undertakes to provide Bio-Techne Corporation, any security holder of Bio-Techne Corporation, or the staff of the Securities and Exchange Commission upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
(2) Each restricted stock unit represents a contingent right to receive one share of Bio-Techne Corporation common stock.
(3) Vests in full or in part on 8/8/2021 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(4) Vests in full or in part on 8/9/2020 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(5) Vests in full or in part on 8/18/19 if certain performance goals are achieved (or such later date as performance is certified by the Administrator)
(6) Vests in full or in part on 8/18/19 if certain performance goals are achieved (or such later date as performance is certified by the Administrator).
(7) 8,750 shares vest on each of 8/12/15, 8/12/16, 8/12/17 and 8/12/18.
(8) Vests 6,023 shares on 8/8/2019 and 6,022 shares each on 8/8/2020, 8/8/2021 and 8/8/20202
(9) Vests 8,153 shares each on 8/19/2018, 8/9/2019, 8/9/2020 and 8,154 on 8/9/2021
(10) 6,250 shares vest on each of 8/7/16, 8/7/17, 8/7/18 and 8/7/19.
(11) Vests 10,134 shares on 8/18/17, and 10,133 shares on each of 8/18/18, 8/18/19 and 8/18/20.

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