Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
FRIEDMAN RICHARD H
  2. Issuer Name and Ticker or Trading Symbol
BioScrip, Inc. [BIOS]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chairman of the Board and CEO
(Last)
(First)
(Middle)
100 CLEARBROOK ROAD
3. Date of Earliest Transaction (Month/Day/Year)
04/29/2008
(Street)

ELMSFORD, NY 10523
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, $.0001 par value 04/29/2008   A   45,000 A $ 0 990,668 D  
Common Stock, $.0001 par value               10,000 I By Shares Held By Ltd Partnership (1)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option to Purchase Common Stock $ 6.52 04/29/2008   A   112,500   04/29/2009(2) 04/29/2018 Common Stock, $.0001 par value 112,500 $ 0 112,500 D  
Employee Stock Option $ 3.46             01/02/2008(2) 01/02/2017 Common Stock, $.0001 par value 200,000   200,000 D  
Employee Stock Option (Right to Buy Common Stock) $ 2.16             10/08/2000(3) 10/08/2009 Common Stock, $.0001 par value 207,806   207,806 D  
Employee Stock Option (Right to Buy Common Stock) $ 2.37             10/08/2000(3) 10/08/2009 Common Stock, $.0001 par value 42,194   42,194 D  
Employee Stock Option (Right to Buy Common Stock) $ 12.2             11/28/2002(3) 11/28/2011 Common Stock, $.0001 par value 200,000   200,000 D  
Employee Stock Option (Right to Buy Common Stock) $ 17.8             01/02/2003(3) 01/02/2012 Common Stock, $.0001 par value 200,000   200,000 D  
Employee Stock Option (Right to Buy Common Stock) $ 5.8             01/02/2004(3) 01/02/2013 Common Stock, $.0001 par value 200,000   200,000 D  
Employee Stock Option (Right to Buy Common Stock) $ 7.54             01/03/2007(2) 01/03/2016 Common Stock, $.0001 par value 200,000   200,000 D  
Employee Stock Option (Right to Buy) $ 7.03             01/02/2005(3) 01/02/2014 Common Stock, $.0001 par value 200,000   200,000 D  
Employee Stock Option (Right to Buy) $ 6.36             01/03/2006(3) 01/03/2015 Common Stock, $.0001 par value 200,000   200,000 D  
Employee Stock Option (Right to Buy) $ 7.7             01/02/2009(2) 01/02/2018 Common Stock, $.0001 par value 130,000   130,000 D  
Employee Stock Option (Right to Buy) $ 7.7             01/02/2009(2) 01/02/2018 Common Stock, $.0001 par value 70,000   70,000 (4) D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
FRIEDMAN RICHARD H
100 CLEARBROOK ROAD
ELMSFORD, NY 10523
  X     Chairman of the Board and CEO  

Signatures

 /s/ Richard H. Friedman   05/01/2008
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Share of Common Stock are owned by the Richard Friedman Family Limited Partnership, of which Mr. Friedman is a general and limited partner. Mr. Friedman has shared voting and dispositive power with respect to these shares of Common Stock.
(2) Vests and becomes exercisable in three equal annual installments commencing on the first anniversary of the date of grant.
(3) Fully Vested
(4) Pursuant to the terms of the Restated Employment Agreement, dated November 29, 2006, between the reporting person and the issuer, the reporting person is entitled to receive a grant of options to purchase 200,000 shares of the issuer's common stock on the first business day of each year. On January 2, 2008 there was an insufficient number of shares remaining available for grant under the issuer's stock option plan to issue the full number of options that the reporting person was entitled to receive on such date. As a result of such shortfall the reporting person was issued options to purchase 130,000 shares. Due to certain option cancellations after January 2, 2008 additional shares became available for grant under the stock option plan and the balance of the 70,000 was issued to the reporting person on February 12, 2008.

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