Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Hides George
 2. Date of Event Requiring Statement (Month/Day/Year)
01/13/2005		 3. Issuer Name and Ticker or Trading Symbol
NORTHFIELD LABORATORIES INC /DE/ [NFLD]
(Last)
(First)
(Middle)
1560 SHERMAN AVE., SUITE 1000		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Vice President
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

EVANSTON, IL 60201		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 1,000 (1)
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (right to buy) (2) 12/06/2004(3) 12/06/2010 Common Stock 3,000 $ 10.66 D  
Stock Option (right to buy) (4) 09/21/2005(5) 09/21/2011 Common Stock 5,000 $ 14.17 D  
Stock Option (right to buy) (6) 10/28/2006(7) 10/28/2012 Common Stock 5,000 $ 5.15 D  
Stock Option (right to buy) (8) 10/20/2007(9) 10/20/2013 Common Stock 7,500 $ 6.5 D  
Stock Option (right to buy) (10) 10/21/2008(11) 10/21/2014 Common Stock 10,000 $ 13.06 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Hides George
1560 SHERMAN AVE.
SUITE 1000
EVANSTON, IL 60201		       Vice President  

Signatures

/s/ George Hides 01/24/2005
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Shares were granted on October 21, 2004 and become fully vested on October 21, 2006.
(2) The Stock Option was granted on December 6, 2000.
(3) The Stock Option becomes fully vested and exercisable as of December 6, 2004.
(4) The Stock Option was granted on September 21, 2001.
(5) The Stock Option becomes fully vested and exercisable as of September 21, 2005.
(6) The Stock Option was granted on October 28, 2002.
(7) The Stock Option becomes fully vested and exercisable as of October 28, 2006.
(8) The Stock Option was granted on October 20, 2003.
(9) The Stock Option becomes fully vested and exercisable as of October 20, 2007.
(10) The Stock Option was granted on October 21, 2004.
(11) The Stock Option becomes fully vested and exercisable as of October 21, 2008.

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