Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
FRIEDMAN RICHARD H
   2. Issuer Name and Ticker or Trading Symbol
BioScrip, Inc. [BIOS] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
100 CLEARBROOK ROAD		 3. Date of Earliest Transaction (Month/Day/Year)
12/01/2011
(Street)

ELMSFORD, NY 10523		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock, $.0001 Par Value 12/01/2011   M V 20,000 (3) A $ 0 337,653 D (2)  
Common Stock, $.0001 Par Value 12/01/2011   S   20,000 D $ 6.0769 (4) 317,653 D (2)  
Common Stock, $.0001 Par Value               250,000 I By The Richard H. Friedman Grantor Retained Annuity Trust (5)

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option To Purchase Common Stock $ 2.73 12/01/2011   M V   20,000 (3) 04/28/2010(1) 05/31/2012 Common Stock, $.0001 Par Value 20,000 $ 0 70,000 D  
Employee Stock Option (Right to Buy) $ 17.8             01/02/2003(6) 01/02/2012 Common Stock, $.0001 Par Value 200,000   200,000 D  
Employee Stock Option (Right to Buy) $ 5.8             01/02/2004 05/31/2012 Common Stock, $.0001 Par Value 91,698   91,698 D  
Employee Stock Option (Right to Buy) $ 7.03             01/02/2005(6) 05/31/2012 Common Stock, $.0001 Par Value 200,000   200,000 D  
Employee Stock Option (Right to Buy) $ 6.36             01/03/2006(6) 05/31/2012 Common Stock, $.0001 Par Value 200,000   200,000 D  
Employee Stock Option (Right to Buy) $ 7.54             01/03/2007(6) 05/31/2012 Common Stock, $.0001 Par Value 200,000   200,000 D  
Employee Stock Option (Right to Buy) $ 3.46             01/02/2008(1) 05/31/2012 Common Stock, $.0001 Par Value 66,667   66,667 D  
Employee Stock Option (Right to Buy) $ 7.7             01/02/2009(1) 05/31/2012 Common Stock, $.0001 Par Value 130,000   130,000 D  
Employee Stock Option (Right to Buy) $ 7.7             01/02/2009(1) 05/31/2012 Common Stock, $.0001 Par Value 70,000   70,000 D  
Option To Purchase Common Stock $ 6.52             04/29/2009(1) 05/31/2012 Common Stock, $.0001 Par Value 112,500   112,500 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
FRIEDMAN RICHARD H
100 CLEARBROOK ROAD
ELMSFORD, NY 10523		   X      

Signatures

 /s/ Richard H. Friedman   12/05/2011
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Vests and becomes exercisable in three equal annual installments commencing on the first anniversary of the date of grant.
(2) Includes 10,000 shares owned jointly with Mr. Friedman's spouse.
(3) These sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on September 15, 2011.
(4) The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $6.00 to $6.13, inclusive. The reporting person undertakes to provide BioScrip, Inc., any security holder of BioScrip, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote.
(5) Shares of Common Stock are owned by the Richard H. Friedman Grantor Retained Annuity Trust dated June 22, 2009. The 250,000 shares held in the trust were transferred to the trust by Mr. Friedman on June 22, 2009. Mr. Friedman is trustee of the trust and has sole voting and dispositive power with respect to these shares of Common Stock.
(6) Fully Vested

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