UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C.  20549

                                    FORM 13F

                              FORM 13F COVER PAGE


                 Report for the Quarter Ended March 31, 2011



                          AMERICAN FINANCIAL GROUP, INC.
                 One East Fourth Street, Cincinnati, Ohio 45202
     -------------------------------------------------------------------------
     (Name and Address of Institutional Investment Manager Filing this Report)


                         Form 13F File Number:  28-4389


The institutional investment manager filing this report and the person by whom
it is signed hereby represent that the person signing the report is authorized
to submit it, that all information contained herein is true, correct and
complete, and that it is understood that all required items, statements,
schedules, lists, and tables, are considered integral parts of this form.

                                 Robert H. Ruffing
                     	   Vice President and Controller
                                   (513) 579-2144
                -----------------------------------------------
                (Name, Title and Phone Number of Person Signing
                 this Report on Behalf of Reporting Manager)



Signature:

/s/Robert H. Ruffing                  Cincinnati, Ohio         May 11, 2011
-------------------------------
Robert H. Ruffing
Vice President and Controller


Report Type:
     [X]  13F HOLDINGS REPORT.
     [ ]  13F NOTICE.
     [ ]  13F COMBINATION REPORT.














                            FORM 13F SUMMARY PAGE
                            ---------------------




Number of Other Included Managers:                         1
                                                      -----------

Form 13F Information Table Entry Total:                   96
                                                      -----------

Form 13F Information Table Value Total (thousands):     $586,301
                                                      -----------



Name and 13F file numbers of all Institutional Investment Managers with respect
to which this schedule is filed (other than American Financial Group, Inc.):

    Number    13F File Number         Name of Subsidiary
    ------    ---------------         ------------------------------------

       1.          28-498             Great American Insurance Company






































                                                       FORM 13F INFORMATION TABLE


                                                             Column 4:   Column 5:                               Column 8:
                                   Column 2:                  Market     Shares or    Column 6: Column 7:    Voting Authority
        Column 1:                  Title of       Column 3:    Value     Principal   Investment    Other ---------------------------
     Name of Issuer                  Class          CUSIP     (000's)      Amount    Discretion Managers    Sole    Shared    None
     --------------             ---------------- ----------- ---------  ------------ ---------- -------- ---------- ------ ---------


HOLDINGS OF GREAT AMERICAN INSURANCE COMPANY
--------------------------------------------
                                                                                                 
ABBOTT LABS			      COM	 002824 10 0	 4,660	    95,000SH   Defined	   1	     95,000
AIR PRODS & CHEMS INC		      COM        009158 10 6	   902	    10,000SH   Defined	   "         10,000
AMERICAN RAILCAR INDS INC             COM        02916P 10 3     1,697      68,000SH   Defined     "         68,000
ANWORTH MORTGAGE ASSET CP             COM        037347 10 1       886     125,000SH   Defined     "        125,000
BANK OF AMERICA CORPORATION           COM        060505 10 4     1,441     108,120SH   Defined     "        108,120
CALAMP CORP                           COM        128126 10 9       468     139,750SH   Defined     "        139,750
CAPITOL FED FINL INC		      COM	 14057J 10 1	   406	    36,000SH   Defined     "         36,000
CHEVRON CORP NEW                      COM        166764 10 0    13,576     126,300SH   Defined     "        126,300
CITIGROUP INC                         COM        172967 10 1     2,652     600,000SH   Defined     "        600,000
COCA COLA CO                          COM        191216 10 0    11,444     172,500SH   Defined     "        172,500
COMCAST CORP NEW                     CL A        20030N 10 1     9,975     403,500SH   Defined     "        403,500
DELTA AIR LINES INC DEL             COM NEW      247361 70 2       397      40,522SH   Defined     "         40,522
DISH NETWORK CORP                    CL A        25470M 10 9       918      37,675SH   Defined     "         37,675
ECHOSTAR CORP                        CL A        278768 10 6       938      24,786SH   Defined     "         24,786
ELLINGTON FINANCIAL LLC               COM        288522 30 3     6,915     300,000SH   Defined     "        300,000
FLAGSTAR BANCORP INC                COM NEW      337930 50 7        25      16,500SH   Defined     "         16,500
FULL HOUSE RESORTS INC		      COM        359678 10 9       135      35,331SH   Defined     "         35,331
HEINZ H J CO                          COM        423074 10 3    10,142     207,750SH   Defined     "        207,750
HEWLETT PACKARD CO		      COM	 428236 10 3     4,916     120,000SH   Defined     "        120,000
INSTEEL INDUSTRIES INC                COM        45774W 10 8       348      24,609SH   Defined     "         24,609
INTEL CORP                            COM        458140 10 0    10,675     529,000SH   Defined     "        529,000
INTERNATIONAL BUSINESS MACHS          COM        459200 10 1    12,353      75,750SH   Defined     "         75,750
JPMORGAN CHASE & CO                   COM        46625H 10 0     5,763     125,000SH   Defined     "        125,000
JOHNSON & JOHNSON                     COM        478160	10 4    13,094     221,000SH   Defined	   "        221,000
KELLOGG CO                            COM        487836 10 8    11,814     218,850SH   Defined     "        218,850
KIMBERLY CLARK CORP                   COM        494368 10 3    13,054     200,000SH   Defined     "        200,000
KRAFT FOODS INC                      CL A        50075N 10 4    14,841     473,250SH   Defined     "        473,250
LOCKHEED MARTIN CORP                  COM        539830 10 9     6,070      75,500SH   Defined     "         75,500
MYR GROUP INC DEL                     COM        55405W 10 4     9,200     384,615SH   Defined     "        384,615
MCDONALDS CORP                        COM        580135 10 1    12,517     164,500SH   Defined     "        164,500
MERCK & CO INC NEW                    COM        58933Y 10 5     8,286     251,000SH   Defined     "        251,000
MICROSOFT CORP                        COM        594918 10 4    11,971     471,500SH   Defined     "        471,500
MOTRICITY INC                         COM        620107 10 2       850      56,525SH   Defined     "         56,525
NATIONAL INTERSTATE CORP              COM        63654U 10 0   212,670  10,200,000SH   Defined     "     10,200,000
O CHARLEYS INC                        COM        670823 10 3       176      29,500SH   Defined     "         29,500
OMEROS CORP                           COM        682143 10 2       816     102,040SH   Defined     "        102,040
PATTERSON UTI ENERGY INC              COM        703481 10 1     1,176      40,000SH   Defined     "         40,000
PEOPLES UNITED FINANCIAL INC	      COM	 712704 10 5     2,013     160,000SH   Defined     "        160,000
PEPSICO INC                           COM        713448 10 8    11,597     180,050SH   Defined     "        180,050
PFIZER INC                            COM        717081 10 3     8,490     418,000SH   Defined     "        418,000
RAYTHEON CO                         COM NEW      755111 50 7     3,841      75,500SH   Defined     "         75,500
TARGET CORP		 	      COM        87612E 10 6     7,502     150,000SH   Defined	   "        150,000
3M CO                                 COM        88579Y 10 1    10,893     116,500SH   Defined     "        116,500
TIME WARNER INC                     COM NEW      887317 30 3       311       8,716SH   Defined     "          8,716
TORTOISE ENERGY CAP CORP              COM        89147U 10 0       728      25,800SH   Defined     "         25,800
VIRGIN MEDIA INC                      COM        92769L 10 1    20,504     737,807SH   Defined     "        737,807
WAL MART STORES INC		      COM        931142 10 3     2,603      50,000SH   Defined     "         50,000
WALGREEN CO                           COM        931422 10 9     9,895     246,500SH   Defined     "        246,500
WELLS FARGO & CO NEW                  COM        949746 10 1     5,708     180,000SH   Defined     "        180,000






HOLDINGS OF OTHER ENTITIES
EACH HAVING LESS THAN
$100 MILLION IN 13F SECURITIES
------------------------------
ACE LTD                               SHS        H0023R 10 5     4,076      63,000SH    Sole                 63,000
AT&T INC                              COM        00206R 10 2       223       7,300SH   Defined     1          7,300
ABBOTT LABS                           COM        002824 10 0       211       4,300SH   Defined	   "          4,300
AMERICAN RAILCAR INDS INC             COM        02916P 10 3     1,687      67,581SH   Defined               67,581
ANWORTH MORTGAGE ASSET CP             COM        037347 10 1       886     125,000SH   Defined              125,000
BANK OF AMERICA CORPORATION           COM        060505 10 4     4,312     323,480SH   Defined     1        323,480
BERKLEY W R CORP                      COM        084423 10 2     3,769     117,000SH    Sole                117,000
BLDRS INDEX FDS TR EMER MK 50         ADR        09348R 30 0     1,205      24,828SH   Defined     1         24,828
BRISTOL MYERS SQUIBB CO               COM        110122 10 8       209       7,900SH   Defined     "          7,900
CALAMP CORP                           COM        128126 10 9       472     140,750SH   Defined              140,750
CHUBB CORP                            COM        171232 10 1     4,353      71,000SH    Sole                 71,000
DPL INC                               COM        233293 10 9       211       7,700SH   Defined     1          7,700
DELTA AIR LINES INC DEL             COM NEW      247361 70 2       390      39,755SH   Defined     "         39,755
DEX ONE CORP                          COM        25212W 10 0        52      10,772SH   Defined               10,772
DISH NETWORK CORP                    CL A        25470M 10 9     1,377      56,512SH   Defined               56,512
EATON VANCE TAX MNG GBL DV E          COM        27829F 10 8       423      40,000SH   Defined     1         40,000
ECHOSTAR CORP                        CL A        278768 10 6     1,407      37,179SH   Defined               37,179
ELLINGTON FINANCIAL LLC               COM        288522 30 3    10,373     450,000SH   Defined              450,000
FLAGSTAR BANCORP INC                COM NEW      337930 50 7        25      16,500SH   Defined               16,500
FULL HOUSE RESORTS INC		      COM        359678 10 9       120      31,617SH   Defined               31,617
INSTEEL INDUSTRIES INC                COM        45774W 10 8       314      22,216SH   Defined               22,216
ISHARES TR                      MSCI EAFE INDEX  464287 46 5     2,186      36,379SH   Defined     1         36,379
ISHARES TR                       s&P MIDSAP 400  462487 50 7       464       4,696SH   Defined     "          4,696
JOHNSON & JOHNSON                     COM        478160 10 4       207       3,500SH   Defined     "          3,500
KEYCORP NEW                           COM        493267 10 8       464      52,222SH   Defined     "         52,222
KIMBERLY CLARK CORP                   COM        494368 10 3       206       3,150SH   Defined     "          3,150
LEGGETT & PLATT INC                   COM        524660 10 7       208       8,500SH   Defined     "          8,500
LILLY ELI & CO                        COM        532457 10 8       211       6,000SH   Defined     "          6,000
LOCKHEED MARTIN CORP                  COM        539830 10 9       205       2,550SH   Defined     "          2,550
MANAGED HIGH YIELD PLUS FD I          COM        561911 10 8        23      10,000SH   Defined     "         10,000
MCDONALDS CORP                        COM        580135 10 1       209       2,750SH   Defined     "          2,750
MERCK & CO INC NEW                    COM        58933Y 10 5       660      20,000SH   Defined               20,000
MOTRICITY INC                         COM        620107 10 2     1,274      84,787SH   Defined               84,787
O CHARLEYS INC                        COM        670823 10 3       267      44,654SH   Defined               44,654
OMEROS CORP                           COM        682143 10 2     1,224     153,061SH   Defined              153,061
PATTERSON UTI ENERGY INC              COM        703481 10 1     1,176      40,000SH   Defined               40,000
PFIZER INC                            COM        717081 10 3       406      20,000SH   Defined               20,000
POWERSHARES ETF TRUST            DYNAMIC MKT PT  73935X 10 4     1,188      25,305SH   Defined     1         25,305
POWERSHARES ETF TRUST            HI YLD EQ DVDN  73935X 30 2       210      23,661SH   Defined     "         23,661
PROCTER & GAMBLE CO                   COM        742718 10 9       203       3,300SH   Defined     "          3,300
REVENUESHARES EFT TR              SMALL CAP FD   761396 30 8       311       8,934SH   Defined     "          8,934
SPDR S&P 500 ETF TR                 TR UNIT      78462F 10 3     5,161      38,926SH   Defined     "         38,926
SELECT SECTOR SPDR TR            SBI MATERIALS   81369Y 10 0       305       7,628SH   Defined     "          7,628
SELECT SECTOR SPDR TR            SBI CONS STPLS  81369Y 30 8       301      10,052SH   Defined     "         10,052
TORTOISE ENERGY CAP CORP              COM        89147U 10 0     2,424      85,900SH   Defined               85,900
VANGUARD INDEX 			  FDS REIT EFT   922908 55 3       646      11,040SH   Defined     1         11,040
VIRGIN MEDIA INC                      COM        92769L 10 1    27,815   1,000,888SH   Defined            1,000,888


                                                             ----------
                                 REPORT TOTAL                 $586,301
                                                             ==========