FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * POSNER BARRY A   2. Issuer Name and Ticker or Trading Symbol BioScrip, Inc. [BIOS] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) Executive Vice President (Last) (First) (Middle) 100 CLEARBROOK ROAD 3. Date of Earliest Transaction (Month/Day/Year) 03/31/2006 (Street) ELMSFORD, NY 10523 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock, $.0001 par value 11/01/2006 11/10/2006 A   79,294 A $ 0 140,294 D   Common Stock, $.0001 par value               2,600 I Joint With Spouse (1)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Employee Stock Option

$ 6

03/31/2006

D

89,700 (2)

02/28/2007(3)

06/30/2015

Common Stock, $.0001 par value

89,700

$ 0

13,800

D

Employee Stock Option

$ 2.47

11/01/2006

11/10/2006

A

158,587

11/01/2007(4)

11/01/2016

Common Stock, $.0001 par value

158,587

$ 0

158,587

D

Employee Stock Option (Right to Buy Common Stock)

$ 6.5

(5)

07/06/2008

Common Stock, $.0001 par value

50,000

50,000

D

Employee Stock Option (Right to Buy Common Stock)

$ 4.5

(5)

12/02/2008

Common Stock, $.0001 par value

13,166

13,166

D

Employee Stock Option (Right to Buy Common Stock)

$ 12.2

11/28/2002(4)

11/28/2011

Common Stock, $.0001 par value

70,000

70,000

D

Employee Stock Option (Right to Buy)

$ 7.95

09/24/2004(4)

09/24/2013

Common Stock, $.0001 par value

75,000

75,000

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
POSNER BARRY A 100 CLEARBROOK ROAD ELMSFORD, NY 10523			Executive Vice President

Signatures

/s/ Posner, Barry A.		11/14/2006
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	These shares of Common Stock are owned jointly with his wife and he shares voting and dispositive power with his wife over these shares
(2)	On 7-1-05 the reporting person was granteed an option to purchase 103,500 shares of common stock. All or part of the option was subject to forfeiture based on Company financial performance and individual qualitative performance criteria for the year ended December 31, 2005. In March 2006, upon final review of the Company's 2005 financial performance a portion of thse options were forfeied by the reporting person.
(3)	Options commence vesting on February 28, 2006. Thereafter, such options vest and become exercisable in three equal annual installments. All or part of these options are subject to forfeiture based on 2005 performance thresholds.
(4)	Vests and becomes exercisable in three equal annual installments commencing on the first anniversary of the date of grant.
(5)	Fully Vested

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