SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549



                                    FORM S-8

                             REGISTRATION STATEMENT
                                      UNDER
                           THE SECURITIES ACT OF 1933


                               ThermoGenesis Corp.
                               -------------------
             (Exact name of registrant as specified in its charter)



            Delaware                                       94-3018487
            --------                                       ----------
(State or other jurisdiction of                          (I.R.S. Employer
 incorporation or organization)                         Identification No.)




                   2711 Citrus Road, Rancho Cordova, CA 95742
                   ------------------------------------------
               (Address of Principal Executive Offices) (Zip Code)


            Amended 2002 Independent Directors Equity Incentive Plan
            --------------------------------------------------------
                            (Full title of the plan)



                              Philip H. Coelho, CEO
                               ThermoGenesis Corp.
                                2711 Citrus Road
                            Rancho Cordova, CA 95742
                            ------------------------
                     (Name and address of agent for service)


                                 (916) 858-5100
                                 --------------
          (Telephone number, including area code, of agent for service)






                         CALCULATION OF REGISTRATION FEE


                                                                                                 

====================================================================================================================

Title of each class of                               Proposed maximum        Proposed maximum
securities to be               Amount to be         offering price per      aggregate offering          Amount of
registered                      registered                share                   price             registration fee
--------------------------------------------------------------------------------------------------------------------

Common Stock                     100,000                  $5.56                  $556,000                $65.45
underlying Amended 2002
Independent Directors
Equity Incentive Plan
reserved for future
issuance

--------------------------------------------------------------------------------------------------------------------

     Total                                                                                               $65.45
====================================================================================================================


(1)  Calculated in accordance with Rule 457(c) of the Securities Act of 1933, as
     amended  ("Securities Act").  Estimated for the sole purpose of calculating
     the  registration  fee and based upon the average of the high and low price
     per share of the common  stock of the  Company  on  February  9,  2005,  as
     reported on the Nasdaq SmallCap Market.





                                     PART II

               INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

Item 3.  Incorporation of Documents by Reference.

     The Securities and Exchange  Commission  rules and regulations  allow us to
"incorporate by reference" the information  that we file with the Securities and
Exchange  Commission.  This  means  that we can  disclose  additional  important
information to you by referring to those documents. The information incorporated
by reference is an important part of this  Prospectus,  and information  that we
file  in  the  future  with  the   Securities  and  Exchange   Commission   will
automatically update and supersede this information. We have filed the following
documents  with the  Securities  and  Exchange  Commission  and the  information
contained in those documents is incorporated by reference into this registration
statement:

(1)     Registrant's  Annual Report on Form 10-K for the fiscal year ended June
        30, 2004;

(2)     Registrant's  Quarterly  Reports  on  Form  10-Q  for the quarters ended
        September 30, 2004 and December 31, 2004;

(3)     Registrant's Proxy Statement for the Annual Meeting held on December 13,
        2004;

(4)     Registrant's  Current  Reports  on  Form 8-K filed on November 10, 2004,
        November 30, 2004, December 15, 2004 and February 9, 2005; and

(5)     The Description of Securities in Item 1 of the Registration Statement on
        Form  8A  for  registration of the Registrant's common stock pursuant to
        Section 12(g) of the Exchange Act.

Item 4.  Description of Securities.

     The  Registrant's  common  stock  to be  offered  under  this  registration
statement is registered under Section 12 of the Exchange Act.

Item 5.  Interests of Named Experts and Counsel.

     The  legality of the shares of common stock  offered  hereby will be passed
upon for the Company by Bartel Eng & Schroder, Sacramento, California.

Item 6.  Indemnification of Directors and Officers.

     The Company is incorporated  in Delaware.  Under Section 145 of the General
Corporation Law of the State of Delaware,  a Delaware  corporation has the power
to  indemnify  its  directors,  officers,  employees  and agents  from  expenses
(including  attorney's fees),  judgments,  fines, and amounts paid in settlement



actually and reasonably  incurred in connection with a threatened,  pending,  or
completed action, suit or proceeding,  whether civil, criminal,  administrative,
or  investigative,  in which such  person is involved by reason of the fact such
person were or are  directors,  officers,  employees  or agents of the  Company,
provided  that such person  acted in good faith and in a manner that such person
reasonably  believed to be in the best interests of the corporation  and, in the
case of a criminal  proceeding,  such person had no reasonable  cause to believe
his or her  conduct was  unlawful.  Such  person may not be  indemnified  if the
person has been adjudged  liable to the  corporation in the  performance of such
person's duties to the corporation, unless the Court of Chancery or the court in
which  such  action  or  suit  was  brought  determines  that,  in  view  of the
circumstances  of the case,  such  person is fairly and  reasonably  entitled to
indemnity.  To the extent that such person has been  successful on the merits or
otherwise in defense of any proceeding,  the General  Corporate Law of the State
of Delaware  provides  that such person shall be  indemnified  against  expenses
(including attorney's fees) reasonably and actually incurred. The Certificate of
Incorporation  and the By-laws of the Company  provide  for  indemnification  of
directors  and  officers  to  the  fullest  extent   permitted  by  the  General
Corporation Law of the State of Delaware.

     The  General  Corporation  Law of the  State of  Delaware  provides  that a
certificate of  incorporation  may contain a provision  eliminating the personal
liability  of a director to the  corporation  or its  stockholders  for monetary
damages for breach of fiduciary duty as a director  provided that such provision
shall not  eliminate or limit the  liability of a director (i) for any breach of
the director's duty of loyalty to the corporation or its stockholders,  (ii) for
acts or omissions not in good faith or which involve intentional misconduct or a
knowing  violation  of law,  (iii) for  unlawful  payment of  dividends or stock
redemption,  or (iv) for any  transaction  from  which the  director  derived an
improper personal benefit. The Company's  Certificate of Incorporation  contains
such a provision.

Item 7.  Exemption from Registration Claimed.

     Not applicable.

Item 8.  Exhibits.

Exhibit Number       Description of Exhibit
--------------       ----------------------
         4.1         Amended 2002 Independent Directors Equity Incentive Plan(1)

         5.1         Opinion of Bartel Eng & Schroder dated February 11, 2005

         23.1        Consent of Bartel Eng & Schroder (contained in Exhibit 5.1)

         23.2        Consent of Ernst & Young LLP, Independent Registered Public
                     Accounting Firm

         (1)  Incorporated by  reference to the Company's current report on Form
              8-K filed on December 15, 2004 (File No. 33-82900).


Item 9.  Undertakings.

(a) The undersigned registrant hereby undertakes:

     (1) To file,  during any period in which  offers or sales are being made, a
post-effective amendment to this registration statement:

          (iii) To include any material  information with respect to the plan of
distribution  not  previously  disclosed  in the  registration  statement or any
material change to such information in the registration statement.

     (2) That, for the purpose of determining any liability under the Securities
Act of 1933,  each  such  post-effective  amendment  shall be deemed to be a new
registration  statement  relating to the  securities  offered  therein,  and the
offering of such  securities at that time shall be deemed to be the initial bona
fide offering thereof.

     (3) To remove from registration by means of a post-effective  amendment any
of the securities being registered which remain unsold at the termination of the
offering.

(b)  The  undersigned   registrant  hereby  undertakes  that,  for  purposes  of
determining  any liability  under the Securities Act of 1933, each filing of the
registrant's  annual  report  pursuant to section  13(a) or section 15(d) of the
Securities  Exchange  Act of 1934  (and,  where  applicable,  each  filing of an
employee  benefit  plan's  annual  report  pursuant  to  section  15(d)  of  the
Securities  Exchange  Act of 1934)  that is  incorporated  by  reference  in the
registration  statement  shall  be  deemed  to be a new  registration  statement
relating to the securities offered therein,  and the offering of such securities
at that time shall be deemed to be the initial bona fide offering thereof.

                                     * * * *

(h) Insofar as indemnification  for liabilities arising under the Securities Act
of 1933 may be permitted to directors,  officers, and controlling persons of the
registrant pursuant to the foregoing  provisions,  or otherwise,  the registrant
has been advised that in the opinion of the Securities  and Exchange  Commission
such  indemnification  is against  public policy as expressed in the Act and is,
therefore,  unenforceable. In the event that a claim for indemnification against
such liabilities  (other than the payment by the registrant of expenses incurred
or paid by a director,  officer,  or controlling person of the registrant in the
successful  defense of any  action,  suit,  or  proceeding)  is asserted by such
director,  officer or controlling person in connection with the securities being
registered, the registrant will, unless in the opinion of its counsel the matter
has been  settled by  controlling  precedent,  submit to a court of  appropriate
jurisdiction  the  question  of whether  such  indemnification  by it is against
public  policy  as  expressed  in the Act  and  will be  governed  by the  final
adjudication of such issue.






                                   SIGNATURES

     Pursuant to the  requirements of the Securities Act of 1933, the registrant
certifies  that it has  reasonable  grounds to believe  that it meets all of the
requirements  for  filing  on Form S-8 and has  duly  caused  this  registration
statement  to be  signed  on its  behalf  by  the  undersigned,  thereunto  duly
authorized, in the City of Rancho Cordova, State of California.

                                                   THERMOGENESIS CORP.,
                                                   a Delaware corporation


Dated: February 11, 2005                    By:    /s/ Philip H. Coelho
       -----------------                           -----------------------------
                                                   Philip H. Coelho,
                                                   Chief Executive Officer and
                                                   Chairman of the Board
                                                   (Principal Executive Officer)

     Pursuant  to  the   requirements  of  the  Securities  Act  of  1933,  this
registration  statement  has  been  signed  by  the  following  persons  in  the
capacities and on the date indicated.



Dated: February 11, 2005                    By:    /s/ Philip H. Coelho
       -----------------                           -----------------------------
                                                   Philip H. Coelho,
                                                   Chief Executive Officer and
                                                   Chairman of the Board
                                                   (Principal Executive Officer)


Dated: February 3, 2005                     By:    /s/ George Barry
       ----------------                            -----------------------------
                                                   George Barry,
                                                   Director


Dated: February 11, 2005                    By:    /s/ Hubert Huckel
       -----------------                           -----------------------------
                                                   Dr. Hubert Huckel
                                                   Director


Dated: February 11, 2005                    By:    /s/ Patrick McEnany
       -----------------                           -----------------------------
                                                   Patrick McEnany,
                                                   Director







Dated: February 11, 2005                    By:   /s/ Kevin Simpson
       -----------------                          ------------------------------
                                                  Kevin Simpson,
                                                  President,  Chief   Operating
                                                  Officer and Director


Dated: February 11, 2005                    By:   /s/ Renee Ruecker
       -----------------                          ------------------------------
                                                  Renee Ruecker,
                                                  Chief Financial Officer
                                                  (Principal Accounting Officer)