UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             WASHINGTON, D.C. 20549

                            SCHEDULE 14A INFORMATION
PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934

Filed by the Registrant |X|

Filed by a Party other than the Registrant |_|

Check the appropriate box:

|_|     Preliminary Proxy Statement

|_|     CONFIDENTIAL,  FOR USE OF THE  COMMISSION  ONLY  (AS  PERMITTED  BY RULE
        14a-6(e)(2))

|X|     Definitive Proxy Statement

|_|     Definitive Additional Materials

|_|     Soliciting Material Pursuant to Rule 14a-12

                               ENZO BIOCHEM, INC.
--------------------------------------------------------------------------------
                (Name of Registrant as Specified in Its Charter)

--------------------------------------------------------------------------------
    (Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)

Payment of Filing Fee (Check the appropriate box):

|X|     No fee required.

|_|     Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and 0-11.

        (1)     Title of each class of securities to which transaction applies:

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        (2)     Aggregate number of securities to which transaction applies:

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        (3)    Per unit price or other underlying value of transaction  computed
               pursuant to Exchange Act Rule 0-11 (set forth the amount on which
               the filing fee is calculated and state how it was determined):

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        (4)     Proposed maximum aggregate value of transaction:

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        (5)     Total fee paid:

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|_|     Fee paid previously with preliminary materials:



|_|     Check box if any part of the fee is offset as provided  by Exchange  Act
        Rule 0-11(a)(2) and identify the filing for which the offsetting fee was
        paid previously.  Identify the previous filing by registration statement
        number, or the Form or Schedule and the date of its filing.

        (1) Amount previously paid:

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        (2)     Form, Schedule or Registration Statement No.:

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        (3)     Filing Party:

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        (4)     Date Filed:

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NOTICE OF ANNUAL MEETING OF SHAREHOLDERS
TO BE HELD ON JANUARY 23, 2007
--------------------------------------------------------------------------------

To the Shareholders of Enzo Biochem, Inc.:

        NOTICE IS HEREBY GIVEN that the Annual Meeting of  Shareholders  of Enzo
Biochem, Inc., a New York corporation (the "Company"),  will be held at The Yale
Club, 50 Vanderbilt  Avenue,  New York, New York 10017,  on January 23, 2007, at
9:00 a.m., local time (the "Annual Meeting"), for the following purposes:

1.      To elect Shahram K. Rabbani and Irwin C. Gerson as Class I Directors for
        a term of three  (3)  years or until  their  respective  successors  are
        elected and qualified;

2.      To  ratify  the  appointment  of  Ernst  &  Young  LLP as the  Company's
        independent  registered  public accounting firm for the Company's fiscal
        year ending July 31, 2007; and

3.      To transact  such other  business as may properly come before the Annual
        Meeting or any adjournment thereof.

        The close of business on November  27, 2006 has been fixed as the record
date for the determination of shareholders  entitled to notice of and to vote at
the Annual Meeting. The transfer books of the Company will not be closed.

        All  shareholders  are cordially  invited to attend the Annual  Meeting.
Please note that you will be asked to present valid picture identification, such
as a driver's  license or passport,  in order to attend the Annual Meeting.  The
use  of  cameras,  recording  devices  and  other  electronic  devices  will  be
prohibited at the Annual Meeting.

        Whether or not you expect to attend, you are requested to sign, date and
return the enclosed proxy promptly.  Shareholders who execute proxies retain the
right to revoke them at any time prior to the voting  thereof by filing  written
notice of such revocation with the Secretary of the Company,  by submission of a
duly  executed  proxy  bearing a later date or by voting in person at the Annual
Meeting of  Shareholders.  Attendance  at the Annual  Meeting will not in and of
itself  constitute  revocation of a proxy.  Any written notice  revoking a proxy
should be sent to Enzo Biochem,  Inc.,  527 Madison  Avenue,  New York, New York
10022,  Attention:  Shahram  K.  Rabbani,  Secretary.  A return  envelope  which
requires  no  postage  if  mailed in the  United  States  is  enclosed  for your
convenience.

                                        By Order of the Board of Directors,


                                        Shahram K. Rabbani, SECRETARY

New York, New York
December 4, 2006



                               ENZO BIOCHEM, INC.
                               527 MADISON AVENUE
                            NEW YORK, NEW YORK 10022
                                 (212) 583-0100

                                   -----------


                                 PROXY STATEMENT

                                   -----------

                         ANNUAL MEETING OF SHAREHOLDERS
                         TO BE HELD ON JANUARY 23, 2007

        This Proxy Statement is furnished in connection with the solicitation by
the Board of  Directors  of Enzo  Biochem,  Inc.,  a New York  corporation  (the
"Company"),  of  proxies  in  the  enclosed  form  for  the  Annual  Meeting  of
Shareholders  to be held at The Yale Club, 50 Vanderbilt  Avenue,  New York, New
York  10017,  on  January  23,  2007,  at 9:00  a.m.,  local  time (the  "Annual
Meeting"), and for any adjournment or adjournments thereof, for the purposes set
forth in the preceding  Notice of Annual  Meeting of  Shareholders.  The persons
named in the  enclosed  form of proxy  will vote the  shares  for which they are
appointed in accordance with the directions of the shareholders appointing them.
In the absence of such directions, such shares will be voted FOR Proposals 1 and
2 listed in the preceding Notice of Annual Meeting of Shareholders and, in their
best judgment,  will be voted on any other matters as may come before the Annual
Meeting.  Any shareholder giving a proxy has the power to revoke the same at any
time before it is voted by timely filing written notice of such  revocation with
the Secretary of the Company,  by timely  submission  of a duly  executed  proxy
bearing a later date or by voting in person at the Annual Meeting. Attendance at
the Annual Meeting will not in and of itself  constitute  revocation of a proxy.
Any written  notice  revoking a proxy should be sent to Enzo Biochem,  Inc., 527
Madison  Avenue,  New York,  New York  10022,  Attention:  Shahram  K.  Rabbani,
Secretary.  A return  envelope  that requires no postage if mailed in the United
States is enclosed for your convenience.

        The expense of the  solicitation  of proxies for the meeting,  including
the cost of mailing, will be borne by the Company. In addition to mailing copies
of the  enclosed  proxy  materials  to  shareholders,  the  Company  may request
persons,  and reimburse them for their expenses with respect  thereto,  who hold
stock in their  names or  custody or in the names of  nominees  for  others,  to
forward  copies of such  materials to those  persons for whom they hold stock of
the  Company and to request  authority  for the  execution  of the  proxies.  In
addition to the solicitation of proxies by mail, it is expected that some of the
officers,  directors and regular  employees of the Company,  without  additional
compensation,  may  solicit  proxies  on  behalf of the  Board of  Directors  by
telephone, telefax and personal interview.

        The  principal  executive  offices  of the  Company  are  located at 527
Madison Avenue,  New York, New York 10022.  The  approximate  date on which this
Proxy Statement and the  accompanying  form of proxy will first be sent or given
to the Company's shareholders is December 4, 2006.

VOTING SECURITIES

        Only  holders  of record of shares of common  stock,  par value $.01 per
share  (the  "Common  Stock"),  of the  Company as of the close of  business  on
November  27,  2006 are  entitled  to vote at the Annual  Meeting  (the  "Record
Date").  On the Record Date there were issued and outstanding  32,361,768 shares
of Common Stock.  Each outstanding  share of Common Stock is entitled to one (1)
vote upon all matters to be acted upon at the Annual  Meeting.  The holders of a
majority of the outstanding shares of Common Stock as of the Record Date must be
present in person or by proxy at the Annual  Meeting to  constitute a quorum for
the transaction of business at the Annual Meeting.

                                       1



        The  election of a nominee for  director  requires a plurality  of votes
(i.e.,  an excess of votes  over those cast for an  opposing  candidate)  in the
event that more than one  candidate is running for a vacancy.  Shareholders  may
either vote "for" or "withhold" their vote for the director nominees. A properly
executed  proxy  marked  "withhold"  with respect to the election of one or more
directors will not be voted with respect to the director or directors,  although
it will be counted for purposes of  determining  whether there is a quorum.  The
ratification and approval of Proposal 2 will require the affirmative vote of the
majority  of the votes  cast by  holders  of shares of Common  Stock  present in
person or  represented  by proxy at the Annual  Meeting and  entitled to vote on
such proposals.  Abstentions and broker  non-votes are not counted as votes cast
on any matter to which they relate and will have no effect on the outcome of the
vote with respect to any matter. A broker non-vote occurs when a broker or other
nominee does not have discretionary  authority and has not received instructions
with respect to a particular proposal.  Proxy ballots are received and tabulated
by the Company's transfer agent and certified by the inspector of election.

HOUSEHOLDING OF ANNUAL MEETING MATERIALS

        Some brokers and other nominee  record holders may be  participating  in
the practice of "householding"  proxy statements.  This means that only one copy
of the  proxy  statement  may  have  been  sent to  multiple  shareholders  in a
shareholder's  household.  The Company will promptly  deliver a separate copy of
the proxy  statement to any  shareholder  who contacts  the  Company's  investor
relations  department at (212) 583-0100 or at the Company's  principal executive
offices at 527 Madison Avenue,  New York, New York 10022 requesting such copies.
If a  shareholder  is receiving  multiple  copies of the proxy  statement at the
shareholder's  household  and would like to  receive a single  copy of the proxy
statement  for a  shareholder's  household  in the future,  shareholders  should
contact their broker,  other nominee  record holder,  or the Company's  investor
relations department to request mailing of a single copy of the proxy statement.

            STOCK OWNERSHIP OF PRINCIPAL SHAREHOLDERS AND MANAGEMENT

        Set forth below is information concerning stock ownership of all persons
known by the  Company  to own  beneficially  5% or more of the  shares of Common
Stock of the  Company,  the  executive  officers  named under  "Compensation  of
Directors  and  Executive  Officers,"  all  directors,  and  all  directors  and
executive  officers  of  the  Company  as a  group  based  upon  the  number  of
outstanding  shares of Common  Stock as of the close of  business  on the Record
Date. Except as otherwise  indicated,  each of the persons named has sole voting
and investment power with respect to the shares shown.


NAME AND ADDRESS OF                     AMOUNT AND NATURE OF          PERCENT
BENEFICIAL OWNER                      BENEFICIAL OWNERSHIP (1)      OF CLASS (2)
-------------------                   ------------------------      ------------
Elazar Rabbani, Ph.D                        2,257,277 (3)               6.9%
Shahram K. Rabbani                          2,189,740 (4)               6.7%
Barry W. Weiner                             1,445,301 (5)               4.4%
Dean Engelhardt, Ph.D                         253,429 (6)                *
Norman E. Kelker, Ph.D                        172,233 (7)                *
John J. Delucca                                82,824 (8)                *
Irwin C. Gerson                                57,190 (8)                *
Melvin F. Lazar, CPA                           70,393 (9)                *
John B. Sias                                  176,660 (10)               *


                                       2



NAME AND ADDRESS OF                     AMOUNT AND NATURE OF          PERCENT
BENEFICIAL OWNER                      BENEFICIAL OWNERSHIP (1)      OF CLASS (2)
-------------------                   ------------------------      ------------
J. Morton Davis                             2,926,769 (11)              9.1%

CAM North America, LLC, Smith               4,215,738 (12)             13.1%
Barney Fund Management LLC,
Salomon Brothers Asset
Management Inc.

All directors and executive officers        7,087,134 (14)             20.6%
as a group (15 persons) (13)

* Less than 1%.

(1)     Except as otherwise  noted,  all shares of Common Stock are beneficially
        owned and the sole  investment  and voting  power is held by the persons
        named, and such persons' address is c/o Enzo Biochem,  Inc., 527 Madison
        Avenue, New York, New York 10022.

(2)     Based upon 32,361,768 shares of Common Stock of the Company  outstanding
        as of the close of business on the Record Date.

(3)     Includes (i) 523,342  shares of Common Stock  issuable upon the exercise
        of options  which are  exercisable  within 60 days from the date hereof,
        (ii) 3,469  shares of Common  Stock  held in the name of Dr.  Rabbani as
        custodian  for certain of his  children,  (iii)  2,168  shares of Common
        Stock held in the name of Dr. Rabbani's wife as custodian for certain of
        their  children,  and (iv) an  aggregate of 5,100 shares of Common Stock
        held in the name of Dr.  Rabbani's  children.  Includes  4,216 shares of
        Common Stock held in the Company's 401(k) plan.

(4)     Includes (i) 523,342  shares of Common Stock  issuable upon the exercise
        of options  which are  exercisable  within 60 days from the date hereof,
        (ii) 1,354 shares of Common Stock held in the name of Mr.  Rabbani's son
        and (iii)  1,671  shares  of  Common  Stock  that Mr.  Rabbani  holds as
        custodian  for certain of his nephews.  Includes  4,180 shares of Common
        Stock held in the Company's 401(k) plan.

(5)     Includes (i) 523,342  shares of Common Stock  issuable upon the exercise
        of options which are exercisable within 60 days from the date hereof and
        (ii) 3,642 shares of Common Stock that Mr. Weiner holds as custodian for
        certain of his children.  Includes  4,223 shares of Common Stock held in
        the Company's 401(k) plan.

(6)     Includes  72,386  shares of Common Stock  issuable  upon the exercise of
        options  which are  exercisable  within  60 days  from the date  hereof.
        Includes 5,442 shares of Common Stock held in the Company's 401(k) plan.

(7)     Includes  58,365  shares of Common Stock  issuable  upon the exercise of
        options  which are  exercisable  within  60 days  from the date  hereof.
        Includes 4,132 shares of Common Stock held in the Company's 401(k) plan.

(8)     Includes 2,500 shares of restricted  Common Stock vesting on January 19,
        2007.  The remaining  shares  represent  Common Stock  issuable upon the
        exercise of options which are  exercisable  within 60 days from the date
        hereof.

(9)     Includes  28,644  shares of Common Stock  issuable  upon the exercise of
        options  which are  exercisable  within  60 days  from the date  hereof.
        Includes  26,249  shares of Common  Stock owned by Mr.  Lazar's wife and
        6,300 shares of Common Stock held in the name of a defined  benefit plan
        for which Mr. Lazar is the sole trustee and beneficiary.  Includes 5,000
        shares of restricted Common Stock vesting on January 19, 2007.  Includes
        4,200 shares in an Individual Retirement Account.

                                       3



(10)    Includes  89,897  shares of Common Stock  issuable  upon the exercise of
        options  which are  exercisable  within  60 days  from the date  hereof.
        Includes 2,500 shares of restricted  Common Stock vesting on January 19,
        2007.

(11)    Mr. Davis'  address is D.H.  Blair  Investment  Banking  Corp.,  44 Wall
        Street, New York, New York 10005.  Includes (i) 30,525 owned directly by
        Mr. Davis,  (ii)  1,419,345  shares of Common Stock owned by D.H.  Blair
        Investment  Banking  Corp.  of which Mr. Davis is the sole  shareholder,
        (iii) 800,670 shares owned by Rosalind Davidowitz, Mr. Davis' wife, (iv)
        663,446  shares  of  Common  Stock  owned by Engex,  Inc.,  a  close-end
        registered  investment company of which Mr. Davis is the Chairman of the
        Board of Directors, and (v) 12,733 shares owned by an investment advisor
        whose  principal  is Mr.  Davis.  This  information  is based  solely on
        Amendment No. 4 to a Schedule 13G filed on February 7, 2006.

(12)    The  address of each entity in the group is 399 Park  Avenue,  New York,
        New York 10022. This information is based solely on a Schedule 13G filed
        on January 10, 2006.

(13)    The total number of directors  and executive  officers  includes six (6)
        executive  officers who were not named under  "Compensation of Directors
        and Executive Officers."

(14)    Includes  2,135,473 shares of Common Stock issuable upon the exercise of
        options which are exercisable within 60 days from the date hereof.

                                   PROPOSAL 1
                              ELECTION OF DIRECTORS

        The Company has three (3) staggered classes of Directors,  each of which
serves for a term of three (3) years. At the Annual Meeting, the Company's Class
I  Directors  will be  elected  to hold  office for a term of three (3) years or
until their  respective  successors are elected and qualified.  Unless otherwise
instructed, the accompanying form of proxy will be voted for the election of the
below-listed  nominees  all of whom  currently  serve as Class I  Directors,  to
continue such service as Class I Directors.  Management has no reason to believe
that any of the nominees will not be a candidate or will be unable to serve as a
director.  However,  in the event  that the  nominees  should  become  unable or
unwilling  to  serve as  directors,  the  form of  proxy  will be voted  for the
election of such  persons as shall be  designated  by the Class II and Class III
Directors.

        Effective November 8, 2006, the total cumulative length of time that any
Outside Director (a member of the Board who is not an officer or employee of the
Company)  may  serve  on the  Board  shall  be  limited  to a  maximum  of three
three-year  terms,  whether  consecutively  or in total,  plus any portion of an
earlier  three-year  term that such Outside  Director may have been appointed to
serve.

                    CLASS I DIRECTOR NOMINEES TO SERVE UNTIL
                      THE 2010 ANNUAL MEETING, IF ELECTED:

                       CLASS I: NEW TERM TO EXPIRE IN 2010

NAME                                  AGE           YEAR FIRST BECAME A DIRECTOR
----                                  ---           ----------------------------
Shahram K. Rabbani                     54                       1976
Irwin C. Gerson                        76                       2001


        THE  BOARD OF  DIRECTORS  OF THE  COMPANY  RECOMMENDS  A VOTE  "FOR" THE
ELECTION  OF  THE  ABOVE-NAMED  NOMINEES.  PROXIES  SOLICITED  BY THE  BOARD  OF
DIRECTORS  WILL BE SO VOTED  UNLESS  SHAREHOLDERS  SPECIFY  IN THEIR  PROXIES  A
CONTRARY CHOICE.

                                       4



                     DIRECTORS WHO ARE CONTINUING IN OFFICE:

                        CLASS II: TERM TO EXPIRE IN 2008

NAME                                  AGE           YEAR FIRST BECAME A DIRECTOR
----                                  ---           ----------------------------
Barry W. Weiner                        56                       1977
John J. Delucca                        63                       1982
Melvin F. Lazar, CPA                   67                       2002


                        CLASS III: TERM TO EXPIRE IN 2009

NAME                                  AGE           YEAR FIRST BECAME A DIRECTOR
----                                  ---           ----------------------------
Elazar Rabbani, Ph.D.                  62                       1976
John B. Sias                           79                       1982


                        DIRECTORS AND EXECUTIVE OFFICERS

        The directors and  executive  officers of the Company are  identified in
the table below. Each executive officer of the Company serves at the pleasure of
the Board of Directors.


                                     YEAR BECAME A
                                      DIRECTOR OR
NAME                          AGE  EXECUTIVE OFFICER  POSITION
----                          ---  -----------------  --------
Elazar Rabbani, Ph.D.         62         1976         Chairman of the Board of
                                                      Directors and Chief
                                                      Executive Officer
Shahram K. Rabbani            54         1976         Chief Operating Officer,
                                                      Treasurer Secretary, and
                                                      Director
Barry W. Weiner               56         1977         President, Chief Financial
                                                      Officer and Director
Carl Balezentis, Ph.D         49         2006         President, Enzo Life
                                                      Sciences, Inc.
Gary C. Cupit, Pharm.D.       59         2006         President, Enzo
                                                      Therapeutics, Inc.
Dean Engelhardt, Ph.D.        66         1981         Executive Vice President
Norman E. Kelker, Ph.D        67         1981         Senior Vice President
Andrew R. Crescenzo           50         2006         Senior Vice President of
                                                      Finance
Herbert B. Bass               58         1995         Vice President of Finance
Barbara E. Thalenfeld, Ph.D.  66         1995         Vice President, Corporate
                                                      Development
David C. Goldberg             49         1995         Vice President, Business
                                                      Development
John J. Delucca               63         1982         Director
John B. Sias                  79         1982         Director
Irwin C. Gerson               76         2001         Director
Melvin F. Lazar, CPA          67         2002         Director

BIOGRAPHICAL INFORMATION REGARDING DIRECTORS AND EXECUTIVE OFFICERS

        DR.  ELAZAR  RABBANI (age 62) Enzo  Biochem's  founder has served as the
Company's  Chairman of the Board of Directors and Chief Executive  Officer since
its inception in 1976. Dr. Rabbani has authored numerous scientific publications
in the field of molecular  biology,  in  particular,  nucleic acid  labeling and
detection.  He is also

                                       5



the lead inventor of many of the Company's  pioneering  patents  covering a wide
range of technologies  and products.  Dr. Rabbani  received his Bachelor of Arts
degree from New York University in Chemistry and his Ph.D. in Biochemistry  from
Columbia University. He is a member of the American Society for Microbiology.

        SHAHRAM  K.  RABBANI  (age  54)  Chief  Operating  Officer,   Treasurer,
Secretary  and  Director,  is a founder and has been with the Company  since its
inception. He is also President of Enzo Clinical Labs. Mr. Rabbani serves on the
New York  State  Clinical  Laboratory  Association,  a  professional  board.  He
received a Bachelor of Arts Degree in Chemistry from Adelphi University, located
in Long Island, New York.

        BARRY  W.  WEINER  (age  56)  President,  Chief  Financial  Officer  and
Director,  is a founder of Enzo  Biochem,  Inc.  He has served as the  Company's
President  since  1996,  and  previously  held the  position of  Executive  Vice
President.  Before his employment with Enzo, he worked in several managerial and
marketing  positions at the Colgate Palmolive Company.  Mr. Weiner is a Director
of the New York  Biotechnology  Association.  He received  his  Bachelor of Arts
degree  in  Economics  from  New  York  University  and  a  Master  of  Business
Administration in Finance from Boston University.

        DR. CARL W. BALEZENTIS (age 49) President, Enzo Life Sciences, Inc., has
held this position since June 2006.  Before his employment with Enzo, he was CEO
of Lark  Technologies,  Inc.  from  2000 to 2004,  prior to its  acquisition  by
Genaissance  Pharmaceuticals,  Inc.  Subsequent to the  acquisition  he held the
positions of President of Lark Technologies,  Inc., and Senior Vice President of
Genaissance.  From 1998 to 2000 he has held numerous executive  positions in the
life  sciences  industry  with  companies  such  as  Sigma-Aldrich,   Perceptive
Scientific Instruments, Inc., Applied Biosystems, Inc. (now Applera) and Promega
Corporation.  Dr.  Balezentis  holds a Ph.D in Genetics  from the  University of
Arizona and completed a Post Doctoral  Fellowship at M.D. Anderson Cancer Center
in Houston, TX.

        DR. GARY C. CUPIT (age 59) President, Enzo Therapeutics, Inc. joined the
Company in October 2006.  Dr. Cupit  previously  held positions as President and
CEO of Sapphire Therapeutics from 2004 to 2006 and Vice President, Global Search
and Evaluation for Novartis  Pharmaceuticals  from 2000 to 2004. Prior positions
include  Business  Development  at  Knoll  Pharmaceuticals,  Vice  President  of
Cardiovascular  Therapeutics at The Medicines  Company and various  positions in
sales,   marketing   and  new  product   development   at   SmithKline   Beecham
Pharmaceuticals.  He earned a Bachelor  of Science in  Pharmacy  at the  Medical
College of Virginia and a Doctor of Pharmacy degree at the Philadelphia  College
of Pharmacy and Science.

        DR. DEAN  ENGELHARDT  (age 66)  Executive  Vice  President has held this
position since July 2000. Since joining the Company in 1981, Dr.  Engelhardt has
held several other executive and scientific  positions  within Enzo Biochem.  In
addition,  Dr.  Engelhardt  has authored many papers in the area of nucleic acid
synthesis and protein  production and has been a featured  presenter at numerous
scientific  conferences  and  meetings.  He holds a Ph.D.  degree  in  Molecular
Genetics from Rockefeller University.

        DR.  NORMAN E.  KELKER  (age 67)  Senior  Vice  President  has held this
position  since 1989.  Before this,  he was the  Company's  Vice  President  for
Scientific  Affairs.  Dr.  Kelker has authored  numerous  scientific  papers and
presentations in the biotechnology  field. He is a member of American Society of
Microbiology  and the American  Association of the  Advancement of Science.  Dr.
Kelker received his Ph.D. in Microbiology  and Public Health from Michigan State
University.

        ANDREW R.  CRESCENZO  (age 50) Senior Vice  President of Finance for the
Company has held this position since May 2006.  Before joining the Company,  Mr.
Crescenzo was an Executive  Director from 2002 to 2006 and a Senior Manager from
1997 to  2003 at  Grant  Thornton  LLP.  From  1993  to 1997 he  served  as Vice
President and Chief Financial Officer of J. D'Addario & Co, Inc and was employed
at Ernst and Young LLP from 1984 to 1993.  Mr.  Crescenzo is a Certified  Public
Accountant  and received his Bachelors of Business  Administration  from Adelphi
University, located in Long Island, New York.

        HERBERT B. BASS (age 58) Vice  President  of Finance for the Company and
is also Senior Vice  President of Enzo  Clinical  Labs.  Before his promotion in
1989 to Vice President of Finance,  Mr. Bass served as the Corporate  Controller
of the  Company.  Mr.  Bass has been with the Company  since 1986.  From 1977 to
1986, Mr. Bass held various positions at Danziger and Friedman, Certified Public
Accountants, the most recent of which was audit

                                       6



manager.  For the  preceding  seven (7)  years,  he held  various  positions  at
Berenson & Berenson,  Certified Public Accountants. Mr. Bass received a Bachelor
of Business  Administration degree in Accounting from Bernard M. Baruch College,
in New York City

        DR.  BARBARA  E.   THALENFELD  (age  66)  Vice  President  of  Corporate
Development  for Enzo Biochem and Vice  President  of Clinical  Affairs for Enzo
Therapeutics.  Dr. Thalenfeld has been employed with the Company since 1982. She
has authored  numerous  scientific  papers in the areas of molecular biology and
genetics,  and  is a  member  of the  American  Society  of  Gene  Therapy,  the
Association  of  Clinical  Research  Professionals,  and  the  Drug  Development
Association.  Dr. Thalenfeld received her Ph.D. at the Institute of Microbiology
at Hebrew  University  in  Jerusalem,  Israel and a Master of Science  degree in
Molecular  Biology  from Yale  University.  She also  completed a Post  Doctoral
Fellowship in the Department of Biological Sciences at Columbia University.

        DAVID C. GOLDBERG (age 49) Vice  President of Business  Development  for
Enzo Biochem and Senior Vice  President of Enzo  Clinical Labs has been employed
with the Company since 1985.  He has held several  managerial  positions  within
Enzo Biochem.  Mr.  Goldberg also held  management and marketing  positions with
DuPont-NEN and Gallard  Schlesinger  Industries  before joining the Company.  He
received a Master of Science degree in Microbiology from Rutgers  University and
a Master of Business Administration in Finance from New York University.

        JOHN J. DELUCCA (age 63) has been a Director of the Company  since 1982,
and is Chairman of the Governance Committee.  From 2003 to 2004, Mr. Delucca was
Executive Vice President and Chief  Financial  Officer of REL Consulting  Group.
Mr. Delucca was the Chief Financial Officer & Executive Vice President,  Finance
& Administration  of Coty, Inc., from 1999 to 2002. From 1993 until 1999, he was
Senior Vice President and Treasurer of RJR Nabisco,  Inc. Mr. Delucca is a board
member,  member of the Compensation  Committee of Endo Pharmaceuticals  Holdings
Inc.  (ENDP:  NasdaqGS),  and  Chairman  of the  Audit  Committees  of Endo  and
ITC^Deltacom  (ITCD.OB).  Endo engages in the  research,  development,  sale and
marketing  of  prescription  pharmaceuticals.  ITC  Deltacom  is a  provider  of
integrated  communication  services  primarily  to  business  customers  in  the
southeastern United States. Mr. Delucca is also a board member and serves as the
Deputy  Chairman  of the Audit  Committee  of British  Energy  (BEYGF.PK)  . Mr.
Delucca holds a BA in Business Administration from Bloomfield College and an MBA
from Fairleigh Dickinson University.

        JOHN B. SIAS (age 79) has been a Director of the Company since 1982. Mr.
Sias had been  President  and Chief  Executive  Officer of Chronicle  Publishing
Company from April 1993 to September  2000.  From January 1986 until April 1993,
Mr. Sias was President of ABC Network Division,  Capital  Cities/ABC,  Inc. From
1977 until January 1986, he was the Executive Vice  President,  President of the
Publishing  Division (which includes  Fairchild  Publications) of Capital Cities
Communications,  Inc.  Mr.  Sias holds a  Bachelor's  degree in  Economics  from
Stanford University.

        IRWIN C. GERSON  (age 76) has been a Director  of the Company  since May
2001, and is Chairman of the  Compensation  Committee.  From 1995 until December
1998, Mr. Gerson served as Chairman of Lowe McAdams Healthcare and prior thereto
had been,  since 1986,  Chairman and Chief Executive  Officer of William Douglas
McAdams,  Inc., one of the largest advertising agencies in the U.S. specializing
in pharmaceutical marketing and communications to healthcare  professionals.  In
February  2000, he was inducted into the Medical  Advertising  Hall of Fame. Mr.
Gerson has a Bachelor of Science in Pharmacy from Fordham  University and an MBA
from the NYU Graduate  School of Business  Administration.  He was a director of
Andrx Corporation, a NASDAQ listed company which specializes in proprietary drug
delivery  technologies  until November 2006. From 1990-1999,  he was Chairman of
the Council of  Overseers of the Arnold and Marie  Schwartz  College of Pharmacy
and has served as a trustee of The Albany  College of  Pharmacy  and Long Island
University.  He was elected  President of the Advisory Board of Florida Atlantic
University Lifelong Learning Society in October 2006.

        MELVIN F. LAZAR,  CPA (age 67) has been a Director of the Company  since
August 2002, the Lead  Independent  Director since October 2005, and is Chairman
of the  Audit  Committee.  Mr.  Lazar  was a  founding  partner  of  the  public
accounting  firm of Lazar,  Levine & Felix LLP from 1969 until October 2002. Mr.
Lazar and his firm served the business and legal  communities for over 30 years.
Mr. Lazar is a board member and chairman of the audit  committee of Arbor Realty
Trust, Inc. (ABR:  NYSE).  Arbor is a real estate investment trust (REIT) formed
to invest in real estate related bridge and mezzanine  loans,  preferred  equity
investments  and other real estate


                                       7



related  assets.  Mr.  Lazar is a board member and serves as the Chairman of the
Audit Committee of Grubb & Ellis Realty Advisors,  Inc. (GAV:AMEX).  The company
is a  development  stage  company  formed  to  acquire  commercial  real  estate
properties.  Mr. Lazar holds a Bachelor of Business  Administration  degree from
The City College of New York (Baruch College).

        Dr.  Elazar  Rabbani and Shahram K.  Rabbani are  brothers  and Barry W.
Weiner is their brother-in-law.

        John J.  Delucca,  John B.  Sais,  Irwin C.  Gerson  and Melvin F. Lazar
qualify as  "independent  directors"  under the criteria  established by the New
York Stock Exchange.

                              CORPORATE GOVERNANCE

        Our Board of Directors  and  management  are  committed  to  responsible
corporate  governance  to ensure that the  Company is managed for the  long-term
benefit of its  shareholders.  To that end,  during  the past year,  as in prior
years,  the Board of Directors and  management  have  periodically  reviewed and
updated,  as  appropriate,  the  Company's  corporate  governance  policies  and
practices.  During the past year,  the Board has also continued to evaluate and,
when  appropriate,  update  the  Company's  corporate  governance  policies  and
practices in accordance with the requirements of the  Sarbanes-Oxley Act of 2002
and the rules  and  listing  standards  issued by the  Securities  and  Exchange
Commission and the New York Stock Exchange ("NYSE").

CORPORATE GOVERNANCE POLICIES AND PRACTICES
-------------------------------------------

        The Company has instituted a variety of policies and practices to foster
and maintain responsible corporate governance, including the following:

        CORPORATE  GOVERNANCE  GUIDELINES  -  The  Board  of  Directors  adopted
        Corporate Governance  Guidelines,  which collect in one document many of
        the corporate  governance practices and procedures that had evolved over
        the  years.  These  guidelines  address  the  duties  of  the  Board  of
        Directors,   director   qualifications  and  selection  process,   Board
        operations,  Board  committee  matters  and  continuing  education.  The
        guidelines also provide for annual self-evaluations by the Board and its
        committees.  The Board reviews these  guidelines on an annual basis. The
        guidelines are available on the Company's  website at www.enzo.com,  and
        in print to any interested party that requests them.

        CORPORATE CODE OF ETHICS - The Company has a Code of Ethics that applies
        to all of the  Company's  employees,  officers and members of the Board.
        The  Code  of  Ethics  is   available  on  the   Company's   website  at
        www.enzo.com, and in print to any interested party that requests them.

        BOARD COMMITTEE CHARTERS - Each of the Company's Audit, Compensation and
        Nominating/Governance  Committees has a written  charter  adopted by the
        Company's Board of Directors that  establishes  practices and procedures
        for such committee in accordance  with applicable  corporate  governance
        rules and  regulations.  The  charters are  available  on the  Company's
        website  at  www.enzo.com,  and in print to any  interested  party  that
        requests them.

        LEAD  INDEPENDENT  DIRECTOR  CHARTER - On October 31, 2005, the Board of
        Directors voted to create the position of Lead  Independent  Director of
        the  Board of  Directors,  to  elect  Melvin  F.  Lazar to serve as Lead
        Independent  Director and adopted a Lead Independent  Director  Charter.
        See  below  for a  description  of  the  responsibilities  of  the  Lead
        Independent Director. The Lead Independent Director Charter is available
        on the Company's website at www.enzo.com, and in print to any interested
        party that requests them.

        DIRECTOR INDEPENDENCE

                REQUIREMENTS   -  The  Board  of  Directors   believes   that  a
                substantial  majority  of its  members  should  be  independent,
                non-employee   directors.   The  Board   adopted  the  following
                "Director  Independence  Standards,"  which are consistent  with
                criteria  established by the New York Stock Exchange,  to assist
                the Board in making these independence determinations.

                                       8



                No  Director  can  qualify  as  independent  if he or she  has a
                material  relationship  with the  Company  outside of his or her
                service  as a  Director  of  the  Company.  A  Director  is  not
                independent if, within the preceding three years:


                        o  The director was an employee of the Company.

                        o  An  immediate  family  member of the  director was an
                           executive officer of the Company.

                        o  A  director  was  affiliated  with or  employed  by a
                           present or former internal or external auditor of the
                           Company.

                        o  An  immediate   family   member  of  a  director  was
                           affiliated   with  or  employed  in  a   professional
                           capacity by a present or former  internal or external
                           auditor of the Company.

                        o  A  director,  or an  immediate  family  member of the
                           director,  received  more than  $100,000  per year in
                           direct  compensation  from the  Company,  other  than
                           director  and  committee  fees and  pension  or other
                           forms of  deferred  compensation  for prior  services
                           (provided such  compensation is not contingent in any
                           way on continued service).

                        o  The  director,  or an immediate  family member of the
                           director,  was  employed as an  executive  officer of
                           another company where any of the Company's executives
                           served on that  company's  compensation  committee of
                           the board of directors.

                        o  The director was an executive officer or employee, or
                           an  immediate  family  member of the  director was an
                           executive  officer,  of  another  company  that  made
                           payments to, or received  payments  from, the Company
                           for property or services in an amount  which,  in any
                           single  fiscal  year,  exceeded  the  greater  of  $1
                           million or two percent  (2%) of such other  company's
                           consolidated gross revenues.

                        o  The  director,  or an immediate  family member of the
                           director, was an executive officer of another company
                           that was  indebted  to the  company,  or to which the
                           Company  was  indebted,  where  the  total  amount of
                           either  company's  indebtedness to the other was five
                           percent (5%) or more of the total consolidated assets
                           of the  company  he or  she  served  as an  executive
                           officer.

                        o  The  director,  or an immediate  family member of the
                           director,  was an  officer,  director or trustee of a
                           charitable  organization  where the Company's  annual
                           discretionary   charitable   contributions   to   the
                           charitable  organization  exceeded  the greater of $1
                           million or five percent  (5%) of that  organization's
                           consolidated gross revenues.

                                       9



               The  Board   has   reviewed   all   material   transactions   and
               relationships  between each director, or any member of his or her
               immediate family, and the Company,  its senior management and its
               independent auditors. Based on this review and in accordance with
               its independence standards outlined above, the Board of Directors
               has  affirmatively   determined  that  all  of  the  non-employee
               directors are independent.

        BOARD NOMINATION POLICIES AND PROCEDURE

                -       NOMINATION   PROCEDURE   -   The   Nominating/Governance
                Committee  is  responsible  for  identifying,   evaluating,  and
                recommending  candidates  for  election  to the Board,  with due
                consideration for  recommendations  made by other Board members,
                the CEO,  shareholders,  and other  sources.  In addition to the
                above  criteria,   the   Nominating/Governance   Committee  also
                considers the  appropriate  balance of experience,  skills,  and
                characteristics  desirable  among the members of the board.  The
                independent     members     of    the    Board     review    the
                Nominating/Governance    Committee   candidates   and   nominate
                candidates for election by the Company shareholders.

                Directors   must  also   possess   the  highest   personal   and
                professional  ethics,  integrity  and values and be committed to
                representing the long-term interests of all shareholders.  Board
                members  are  expected to  diligently  prepare  for,  attend and
                participate in all Board and applicable Committee meetings. Each
                Board  member is  expected  to ensure  that other  existing  and
                future commitments do not materially interfere with the member's
                service as a director.

                The  Nominating/Governance  Committee  also  reviews  whether  a
                potential   candidate  will  meet  the  Company's   independence
                standards  and  any  other  director  or  committee   membership
                requirements imposed by law, regulation or stock exchange rules.

                Director candidates  recommended to the Committee are subject to
                full Board approval and subsequent election by the shareholders.
                The  Board  of  Directors  is  also   responsible  for  electing
                directors  to fill  vacancies  on the  Board  that  occur due to
                retirement, resignation, expansion of the Board or other reasons
                between    the     Shareholders'     annual    meetings.     The
                Nominating/Governance  Committee may retain a recruitment  firm,
                from  time to time,  to  assist in  identifying  and  evaluating
                director candidates. When a firm is used, the Committee provides
                specified  criteria  for  director  candidates,  tailored to the
                needs  of the  Board at that  time,  and pays the firm a fee for
                these  services.  Suggestions  for director  candidates are also
                received from board members and  management and may be solicited
                from professional associations as well.

        BOARD COMMITTEES

                -       All  members  of each of the  Company's  three  standing
                committees - the Audit, Compensation,  and Nominating/Governance
                - are  required  to  be  independent  in  accordance  with  NYSE
                criteria. See below for a description of the responsibilities of
                the Board's standing committees.

        EXECUTIVE SESSIONS OF NON-MANAGEMENT DIRECTORS

                -       The   Board   and   the    Audit,    Compensation    and
                Nominating/Governance  Committees  periodically hold meetings of
                only the  independent  directors  or Committee  members  without
                management present.

        LEAD INDEPENDENT DIRECTOR

                -       The  duties  of the Lead  Independent  Director,  as set
                forth in the Lead  Independent  Director  Charter,  among  other
                things,  are to develop the agendas for and serve as chairman of
                the  executive  sessions  of the  independent  directors  of the
                Company;  serve as  principal  liaison  between

                                       10



                the independent directors of the Company and the Chairman of the
                Board  and  between  the   independent   directors   and  senior
                management;  provide the  Chairman of the Board with input as to
                the  preparation of the agendas for Board  meetings;  advise the
                Chairman of the Board as to the quality, quantity and timeliness
                of the information submitted by the Company's management that is
                necessary  or  appropriate  for  the  independent  directors  to
                effectively  and responsibly  perform their duties;  ensure that
                independent  directors have adequate  opportunities  to meet and
                discuss issues in executive sessions without management present;
                if the  Chairman  of the  Board is  unable  to attend a Board of
                Directors  meeting,  act as chairman of such Board of  Directors
                meeting; and perform such other duties as the Board of Directors
                shall from time to time delegate. On October 31, 2005, the Board
                of  Directors  elected  Melvin  F.  Lazar  to  serve as the Lead
                Independent Director.

        BOARD ACCESS TO INDEPENDENT ADVISORS

                -       The Board as a whole,  and each of the Board  committees
                separately,   have   authority  to  retain  and  terminate  such
                independent consultants,  counselors or advisors to the Board as
                each shall deem necessary or appropriate.

        COMMUNICATIONS WITH BOARD OF DIRECTORS

                -       DIRECT COMMUNICATIONS - Any interested party desiring to
                communicate  with the Board of  Directors  or with any  director
                regarding  the Company  may write to the Board or the  director,
                c/o Shahram K. Rabbani,  Office of the Secretary,  Enzo Biochem,
                Inc., 527 Madison Avenue, New York New York 10022. The Office of
                the  Secretary  will  forward  all  such  communications  to the
                director(s).  Interested  parties  may also  submit  an email by
                filling  out  the  email  form  on  the  Company's   website  at
                www.enzo.com.  Moreover,  any  interested  party may contact the
                non-management  directors of the Board and/or the  presiding (or
                lead) director.

                -       ANNUAL MEETING - The Company encourages its directors to
                attend the annual  meeting of  shareholders  each year.  Messrs.
                Delucca,  Sias,  Gerson and Lazar attended the Annual Meeting of
                Shareholders held in January 2006.

        MEETINGS OF THE BOARD OF DIRECTORS AND ITS COMMITTEES

        During  the  fiscal  year  ended  July 31,  2006,  there were six formal
meetings of the Board of  Directors,  several  actions by unanimous  consent and
several   informal   meetings.   Currently,   the  Board  of  Directors   has  a
Nominating/Governance   Committee,   an  Audit   Committee  and  a  Compensation
Committee. The Nominating/Governance Committee had one formal meeting, the Audit
Committee  had four formal  meetings  and the  Compensation  Committee  had four
formal meetings.

        The Audit  Committee was established by and among the Board of Directors
for the purpose of overseeing the accounting and financial  reporting  processes
of the  Company  and  audits  of the  financial  statements  of the  Company  in
accordance with Section  3(a)(58)(A) of the Securities  Exchange Act of 1934, as
amended,  The Audit Committee is authorized to review proposals of the Company's
auditors  regarding annual audits,  recommend the engagement or discharge of the
auditors,   review   recommendations  of  such  auditors  concerning  accounting
principles and the adequacy of internal  controls and accounting  procedures and
practices,  review the scope of the annual  audit,  approve or  disapprove  each
professional service or type of service other than standard auditing services to
be provided  by the  auditors,  and review and  discuss  the  audited  financial
statements  with the auditors.  The current  members of the Audit  Committee are
Messrs.  Lazar, Delucca and Gerson, and Mr. Lazar is the Chairman.  The Board of
Directors  has  determined  that  each  of  the  Audit  Committee   members  are
independent,  as defined in the NYSE's listing  standards and as defined in Item
7(d)(3)(iv)  of Schedule 14A under the  Securities and Exchange Act of 1934. The
Board of Directors  has further  determined  that Messrs.  Delucca and Lazar are
each "audit  committee  financial  experts"  as such term is defined  under Item
401(h)(2) of Regulation S-K.

                                       11



        The Compensation  Committee has the power and authority to (i) establish
a general compensation policy for the officers and employees of the Corporation,
including to  establish  and at least  annually  review  officers'  salaries and
levels of officers' participation in the benefit plans of the Corporation,  (ii)
prepare any reports that may be required by the  regulations  of the  Securities
and Exchange  Commission or otherwise  relating to officer  compensation,  (iii)
approve any increases in directors'  fees, (iv) grant stock options and/or other
equity  instruments (v) exercise all other powers of the Board of Directors with
respect to matters  involving  the  compensation  of employees  and the employee
benefits of the  Corporation  as shall be delegated by the Board of Directors to
the Compensation  Committee.  The current members of the Compensation  Committee
are Messrs. Gerson, Sias and Lazar and Mr. Gerson is the Chairman.

        The  Nominating/Governance  Committee  has the power to recommend to the
Board of  Directors  prior to each  annual  meeting of the  shareholders  of the
Corporation: (i) the appropriate size and composition of the Board of Directors;
and (ii)  nominees:  (1) for  election  to the Board of  Directors  for whom the
Corporation  should solicit proxies;  (2) to serve as proxies in connection with
the annual shareholders'  meeting; and (3) for election to all committees of the
Board  of  Directors  other  than  the   Nominating/Governance   Committee.  The
Nominating/Governance Committee will consider nominations from the shareholders,
provided  that  they are made in  accordance  with the  Company's  By-laws.  The
current  members of the  Nominating/Governance  Committee  are Messrs.  Delucca,
Lazar and Sias and Mr. Delucca is the Chairman.

AUDIT COMMITTEE REPORT

        In connection with the  preparation  and filing of the Company's  Annual
Report on Form 10-K for the year ended July 31, 2006:

                (1)     The Audit  Committee  reviewed and discussed the audited
                financial statements with management;

                (2)     The  Audit  Committee  discussed  with  the  independent
                auditors  matters  required to be discussed  under  Statement on
                Auditing Standards No. 61, as may be modified or supplemented;

                (3)     The Audit Committee reviewed the written disclosures and
                the  letter  from  the  independent  auditors  required  by  the
                Independence  Standards Board Standard No. 1, as may be modified
                or supplemented, and discussed with the independent auditors any
                relationships that may impact their objectivity and independence
                and satisfied itself as to the auditors' independence;

                (4)     The  Audit   Committee   discussed  with  the  Company's
                independent  auditors the overall scope and plans for its audit.
                The Audit Committee met with the independent auditors,  with and
                without  management  present,  to discuss  the  results of their
                examinations,   their  evaluations  of  the  Company's  internal
                controls,  and the overall  quality of the  Company's  financial
                reporting.  The Audit Committee held four formal meetings during
                the fiscal year ended July 31, 2006 and

                (5)     Based on the review and  discussions  referred to above,
                the Audit  Committee  recommended to the Board of Directors that
                the audited  financial  statements of the Company be included in
                the 2006 Annual Report on Form 10-K.

                             Submitted by the members of the Audit Committee

                                           Melvin F. Lazar, CPA
                                           John J. Delucca
                                           Irwin C. Gerson

SECTION 16(A) BENEFICIAL OWNERSHIP REPORTING COMPLIANCE

        Section  16(a)  of the  Securities  Exchange  Act of 1934,  as  amended,
requires  the   Company's   executive   officers,   directors  and  persons  who
beneficially  own more than 10% of a registered  class of the  Company's  equity

                                       12



securities  (collectively,  "Reporting Persons") to file with the Securities and
Exchange  Commission  initial  reports of  ownership  and  reports of changes in
ownership  of common  stock and other equity  securities  of the  Company.  Such
executive  officers,  directors  and  greater  than 10%  beneficial  owners  are
required by Securities and Exchange Commission regulation to furnish the Company
with copies of all Section 16(a) forms filed by such reporting persons.

        Based  solely on the  Company's  review of such forms  furnished  to the
Company and written  representations from certain reporting persons, the Company
believes that the Reporting  Persons have  complied with all  applicable  filing
requirements,  except  that  Messrs.  Delucca,  Gerson,  Lazar,  Sias,  Bass and
Goldberg and Dr. Thalenfeld each filed one report late.

CERTAIN RELATIONSHIP AND RELATED TRANSACTIONS

        Enzo Clinical  Labs,  Inc.  ("Enzo  Lab"),  a subsidiary of the Company,
leases a  facility  located  in  Farmingdale,  New  York  from  Pari  Management
Corporation  ("Pari").  Pari is owned equally by Elazar Rabbani,  Ph.D., Shahram
Rabbani and Barry Weiner and his wife,  the officers and directors of Pari.  The
lease originally commenced on December 20, 1989, but was amended and extended in
March 2005 and now  terminates on March 31, 2017.  During fiscal 2006,  Enzo Lab
paid approximately  $1,337,000 (including $172,000 in real estate taxes) to Pari
with respect to such facility and future  payments are subject to cost of living
adjustments.  The Company,  which has guaranteed Enzo Lab's  obligations to Pari
under the lease,  believes that the existing lease terms are as favorable to the
Company as would be available from an unaffiliated party.

CODE OF ETHICS

        The  Company  has  adopted a Code of Ethics  (as such term is defined in
Item 406 of  Regulation  S-K).  The Code of Ethics is available on the Company's
website at www.enzo.com, and in print to any shareholder that requests them. The
Code of Ethics  applies to the  Company's  Executive  Officer,  Chief  Financial
Officer and principal  accounting  officer or controller,  or persons performing
similar functions.  The Code of Ethics has been designed to deter wrongdoing and
to promote:

(1)     Honest and ethical conduct,  including the ethical handling of actual or
        apparent   conflicts  of  interest  between  personal  and  professional
        relationships;

(2)     Full, fair, accurate,  timely, and understandable  disclosure in reports
        and documents that the Company files with, or submits to, the Securities
        and Exchange  Commission and in other public  communications made by the
        Company;

(3)     Compliance with applicable governmental laws, rules and regulations;

(4)     The prompt internal  reporting or violations of the Code of Ethics to an
        appropriate person or persons identified in the Code of Ethics; and

(5)     Accountability for adherence to the Code of Ethics.

                                       13



                COMPENSATION OF DIRECTORS AND EXECUTIVE OFFICERS

        The  following  summary  compensation  table  sets  forth the  aggregate
compensation  paid by the  Company  to its chief  executive  officer  and to the
Company's  four other most highly  compensated  executive  officers whose annual
compensation  exceeded $100,000 for the fiscal year ended July 31, 2006 (each, a
"Named  Executive  Officer") for services during the fiscal years ended July 31,
2006, 2005 and 2004:

                           SUMMARY COMPENSATION TABLE



                                                                   LONG TERM
                                                                  COMPENSATION
                                                                     AWARDS
                                                                  ------------
            NAME AND                     ANNUAL COMPENSATION
       PRINCIPAL POSITION              ----------------------      SECURITIES
       ------------------                                         UNDERLYING
                               YEAR    SALARY ($)   BONUS ($)   OPTIONS/SARS (#)
                               ----    ----------   ---------   ----------------

Elazar Rabbani, Ph.D.,         2006     $458,315     $237,000        -0-
  CHAIRMAN OF THE BOARD OF     2005     $442,200     $283,250       50,000
  DIRECTORS AND CEO            2004     $430,942     $275,000       78,750

Shahram K. Rabbani,            2006     $420,192     $175,000        -0-
  CHIEF OPERATING OFFICER,     2005     $405,423     $267,800       50,000
  TREASURER, SECRETARY AND     2004     $395,046     $260,000       78,750
  DIRECTOR

Barry W. Weiner,               2006     $420,192     $200,000        -0-
  PRESIDENT, CHIEF FINANCIAL   2005     $405,423     $267,800       50,000
  OFFICER AND DIRECTOR         2004     $395,046     $260,000       78,750

Dean Engelhardt, Ph.D.,        2006     $240,039     $55,000         -0-
  EXECUTIVE VICE PRESIDENT     2005     $231,624     $55,000        10,000
                               2004     $225,737     $55,000        15,750

Norman E. Kelker, Ph.D.,       2006     $207,388     $35,000         -0-
  SENIOR VICE PRESIDENT        2005     $200,104     $45,000        10,000
                               2004     $202,476     $45,000        15,750


OPTION/SAR GRANTS IN LAST FISCAL YEAR

        There were no stock  option/SAR  grants to the Named Executive  Officers
during the fiscal year ended July 31, 2006.

AGGREGATED OPTION/SAR EXERCISES IN LAST FISCAL YEAR AND FISCAL YEAR-END
OPTION/SAR VALUES

        The following table sets forth certain information with respect to stock
option  exercises by the Named  Executive  Officers during the fiscal year ended
July  31,  2006 and the  value of  unexercised  options  held by them at  fiscal
year-end.

                                       14



                                                NUMBER OF
                                               SECURITIES
                                               UNDERLYING           VALUE OF
                                               UNEXERCISED        UNEXERCISED
                                              OPTIONS/SARS        IN-THE-MONEY
                                               OPTIONS AT       OPTIONS/SARS AT
                                             FISCAL YEAR-END    FISCAL YEAR-END
                                                   (#)              ($) (1)
                                             ----------------  -----------------
                        SHARES
                      ACQUIRED ON    VALUE
                       EXERCISE    REALIZED   EXER-   UNEXER-   EXER-    UNEXER-
NAME                      (#)         ($)    CISABLE  CISABLE  CISABLE   CISABLE
----                  -----------  --------  -------  -------  -------   -------

Elazar Rabbani, Ph.D.   67,005    $126,170   523,342    -0-   $1,051,286   $0
Shahram K. Rabbani      67,005    $126,170   523,342    -0-   $1,051,286   $0
Barry W. Weiner         67,005    $126,170   523,342    -0-   $1,051,286   $0
Dean Engelhardt, Ph.D.  20,101     $37,850    72,386    -0-    $133,670    $0
Norman E. Kelker, Ph.D                                         $119,029    $0

    (1) Market value of the  underlying  securities at fiscal year end minus the
        exercise price paid in cash or stock.

        On June 3, 2005 the Board of Directors unanimously approved a resolution
to immediately  accelerate the  effectiveness of all unvested stock options that
were  "out of the  money"  by $1.50 or more  based on the  closing  price of the
Company's  Common  Stock  on the  date of the  resolution.  As a  result  of the
acceleration,  options to purchase approximately 666,000 shares of the Company's
common stock (which represented  approximately 21% of the Company's  outstanding
stock  options)  became  exercisable  immediately.  The total  number of options
subject to  acceleration  included  options to purchase  575,000  shares held by
executive officers and directors of the Company.  This action was taken to avoid
expense recognition in future financial statements upon adoption of SFAS 123(R).

EMPLOYMENT AGREEMENTS

        Each of Mr. Barry Weiner,  Mr.  Shahram  Rabbani and Dr. Elazar  Rabbani
(the "Executives") are parties to a employment agreements effective May 4, 1994,
as  amended  as of July  13,  2000  (the  "Employment  Agreement(s)"),  with the
Company.  Pursuant  to the  terms of  their  respective  Employment  Agreements,
Messrs.  Weiner and Rabbani and Dr.  Rabbani are currently  compensated  for the
calendar year 2006 at a base annual  salary of $427,300,  $427,300 and $466,100,
respectively.  Each Executive  will also receive an annual bonus,  the amount of
which shall be  determined  by the Board of  Directors in its  discretion.  Each
Employment Agreement provides that, in the event of termination of employment by
the Executive for "good  reason," or a termination  of employment by the Company
without "cause" or, additionally, a nonrenewal, as such terms are defined in the
Employment  Agreement,  each Executive shall be entitled to receive:  (a) a lump
sum in an amount equal to three years of the Executive's base annual salary; (b)
a lump sum in an amount  equal to the annual  bonus  paid by the  Company to the
Executive  for the last fiscal year of the Company  ending  prior to the date of
termination  multiplied by three;  (c) insurance  coverage for the Executive and
his  dependents,  at the same level and at the same charges to the  Executive as
immediately prior to his termination,  for a period of three (3) years following
his  termination  from the  Company;  (d) all  accrued  obligations,  as defined
therein;  and (e) with  respect to each  incentive  pay plan  (other  than stock
option or other equity plans) of the Company in which the Executive participated
at the time of  termination,  an amount equal to the amount the Executive  would
have earned if he had continued  employment for three  additional  years. If the
Executive is  terminated  by reason of his  disability,  he shall be entitled to
receive, for three years after such termination, his base annual salary less any
amounts  received  under  a long  term  disability  plan.  If the  Executive  is
terminated by reason of his death, his legal  representatives  shall receive the
balance of any remuneration due him under the terms of his Employment Agreement.
The term of each of the Executive's  Employment  Agreement  currently expires on
May 4, 2008, which term automatically  renews for successive two year periods if
notice to the Company is not given by either party within 180 days of the end of
such successive term.

COMPENSATION OF DIRECTORS

        As of November 1, 2005, the Lead Independent Director receives an annual
director's fee of $50,000 and each other person who serves as a director and who
is not otherwise an officer or an employee (such director being classified as an
"Outside  Director")  of the  Company,  receives  an  annual  director's  fee of
$20,000.  For each  meeting of the Board of  Directors  attended in person or by
telephone, the Lead Independent Director and all other Outside

                                       15



Directors  receive a fee of $2,000.  Additionally,  each  Outside  Director  who
serves on a  committee  of the Board of  Directors  receives a fee of $1,000 for
each meeting of the committee attended in person or by telephone. In addition to
the $1,000 per  committee  meeting  fee,  the  Chairman  of the Audit  Committee
receives an  additional  fee of $1,000 for each  meeting of the Audit  Committee
attended in person or by telephone,  the Lead Independent  Director  receives an
additional  fee of $500 for each  meeting  of any Board  committee  attended  in
person or by telephone,  and the Chairman of the Compensation  Committee and the
Chairman of the Nominating/Governance  Committee each receives an additional fee
of $500 for each meeting of the  committee  attended in person or by  telephone.
The Lead Independent  Director will receive  restricted stock units  immediately
following the Annual Meeting,  provided such person is a director of the Company
at such time. Each of the other Outside Directors will receive  restricted stock
units  immediately  following  the Annual  Meeting,  provided  such  person is a
director of the Company at such time. The number of restricted  stock units that
the Lead Independent  Director and each of the Outside Directors receive will be
determined  on an  annual  basis  by the  Compensation  Committee.  Each  of the
restricted  stock units referred to above shall be subject to a two-year vesting
period;  provided  that at the time any  non-employee  director  ceases  to be a
director of the Company (other than due to such  director's  resignation),  such
non-employee director's restricted stock units shall become fully vested at such
time. The Company reimburses  directors for their travel and related expenses in
connection with attending  meetings of the Board of Directors and  Board-related
activities.

COMPENSATION COMMITTEE INTERLOCKS AND INSIDER PARTICIPATION

        The current members of the  Compensation  Committee are Messrs.  Gerson,
Sias and Lazar. No member of the Compensation  Committee has a relationship that
would  constitute an  interlocking  relationship  with the  Company's  executive
officers or other directors.

COMPENSATION COMMITTEE REPORT

        The Company strives to apply a uniform  philosophy to  compensation  for
all of its  employees,  including  the  members of its senior  management.  This
philosophy is based on the premise that the  achievements  of the Company result
from the combined and coordinated efforts of all employees working toward common
goals and objectives.

        The  goals  of  the   Company's   compensation   program  are  to  align
remuneration with business objectives and performance, and to enable the Company
to retain and  competitively  reward  executive  officers who  contribute to the
long-term  success  of the  Company.  The  Company's  compensation  program  for
executive officers is based on the following principles, which are applicable to
compensation decisions for all employees of the Company. The Company attempts to
pay its executive officers competitively in order that it will be able to retain
the most capable people in the industry.  Information  with respect to levels of
compensation  being  paid by  comparable  companies  is  obtained  from  various
publications and surveys.

        During the last fiscal year,  the  compensation  of  executive  officers
consisted  principally of salary and bonus.  The Company may grant stock options
and/or other equity  compensation to certain of its executive  officers,  in the
future.  The cash  portion  of such  program  includes  base  salary  and annual
bonuses,  which are awarded in the discretion of the Board of Directors.  Salary
levels  have  been set based  upon  historical  levels,  amounts  being  paid by
comparable companies and performance.  The Company's  equity-based  compensation
consists of the award of  discretionary  stock  options,  which are  designed to
provide  additional  incentives  to executive  officers to maximize  shareholder
value.  Through  the use of  extended  vesting  periods,  the option  program is
designed to encourage executive officers to remain in the employ of the Company.
In addition, because the exercise prices of such options are typically set at or
above  the fair  market  value of the stock on the date the  option is  granted,
executive  officers can only  benefit from such options if the trading  price of
the Company's  shares of Common Stock  increases,  thus aligning their financial
interests directly with those of the shareholders.

        In consideration  for Dr. Elazar  Rabbani's  services as Chairman of the
Board of  Directors  and Chief  Executive  Officer of the Company for the fiscal
year ended July 31,  2006,  the  Company  paid Dr.  Rabbani an annual  salary of
$458,315 and a bonus of $237,000.  Such compensation was determined  pursuant to
the Company's employment agreement with Dr. Rabbani and was based on the Board's
view of Dr. Rabbani's  successful  performance as Chief Executive  Officer.  See
"Employment Agreements."

                                       16



                          Submitted by the members of the Compensation Committee


                          Irwin W. Gerson
                          John J. Delucca
                          Melvin F. Lazar


401(K) PLAN

        The Company has adopted a salary  reduction profit sharing plan which is
generally  available  to  employees  of the  Company and any  subsidiary  of the
Company.  Officers and directors who are employees of the Company participate in
the Plan on the same basis as other employees.

        The Plan permits voluntary contributions by employees in varying amounts
up to 17% of  annual  earnings  (not to  exceed  the  maximum  allowable  in any
calendar  year  which  is  $15,000  for  2006,  exclusive  of  allowed  catch-up
contributions,  as defined). Employee contributions are made by salary reduction
under  Section  401(k) of the  Internal  Revenue  Code of 1986,  as amended (the
"Code"),  and are excluded from taxable income of the employee.  The Company may
also contribute additional discretionary amounts as it may determine.

        All employees of the Company who are twenty-one  (21) years or older and
have been employed by the Company for a minimum of three (3) months are eligible
to participate in the Plan.  Employees,  who have more than 500 hours of service
per  service  year,  but less than  1,000  hours  per  service  year,  are still
considered  members of the Plan, but  contribution  allocations and vesting will
not increase during such time.

        A  participant's  account  is  distributed  to him  upon  retirement  or
termination   of  employment  for  any  reason  and  in  certain  other  limited
situations.  The amount of the Plan  allocation  attributable  to the  Company's
discretionary  contributions  will vest in accordance  with a schedule.  For the
fiscal year ended July 31, 2006,  the Company has made  contributions  of 50% of
the employees'  contribution up to 10% of the employees'  compensation in Common
Stock of the Company.

1999 STOCK OPTION PLAN

        Under the  Company's  1999  Stock  Option  Plan (the "1999  Plan"),  the
Company's  Board of Directors may grant  incentive  stock  options  ("ISOs") and
non-qualified  stock  options  ("NQSOs") to selected key  employees,  directors,
executive  officers,  consultants  and  advisors of the Company to purchase  the
Company's  Common Stock.  ISOs and NQSOs  granted under the 1999 Plan  generally
vest no earlier than six (6) months after the date of grant and can be exercised
no later than the tenth (10th)  anniversary date of the date of grant.  When the
optionee,  however,  holds  more than 10% of all  combined  voting  stock of the
Company,  ISOs granted  under the 1999 Plan cannot be  exercised  later than the
fifth  (5th)  anniversary  date of the date of  grant.  The  exercise  prices of
options  granted  under the 1999 Plan are set by the Board of  Directors  of the
Company, or designated committee.  In any event, however, ISOs granted under the
1999 Plan may not be  exercisable at a price lower than the fair market value of
the Company's  Common Stock on the date such options are granted,  and, when the
optionee  holds more than 10% of all combined  voting stock of the Company,  the
exercise  prices of such  options  may not be less than 110% of the fair  market
value of the  Common  Stock of the  Company on the date of grant.  ISOs  granted
under the 1999 Plan to any optionee which become  exercisable for the first time
in any one  calendar  year for  shares of Common  Stock of the  Company  with an
aggregate  fair market value,  as of the respective  date or dates of grant,  of
more than $100,000 shall be treated as NQSOs. The awards under the 1999 Plan are
subject  to  restrictions  on   transferability,   are  forfeitable  in  certain
circumstances  and are  exercisable at such time or times and during such period
as shall be set forth in the option agreement evidencing such option. During the
fiscal year ended July 31, 2006, no options to purchase  shares of the Company's
Common Stock were  awarded  under the 1999 Plan.  As of the Record Date,  of the
2,187,224  shares of the Company's  Common Stock  reserved for issuance upon the
exercise of options  authorized for grant under the 1999 Plan,  62,308 shares of
the  Company's  Common Stock remain  available for issuance upon the exercise of
options authorized for grant under the 1999 Plan.

                                       17



AMENDED AND RESTATED 2005 EQUITY COMPENSATION INCENTIVE PLAN

        Under the  Company's  2005  Amended  and  Restated  Equity  Compensation
Incentive  Plan (the "2005 Plan"),  the  Company's  Board of Directors may grant
incentive stock options ("ISOs"),  non-qualified stock options ("NQSOs"), awards
of restricted  stock,  restricted  stock units and dividend  equivalents  to the
Company's  directors,   officers,  employees  and  other  persons  that  provide
consulting or advisory services to us and our subsidiaries. Under the 2005 Plan,
the  maximum  number  of shares of common  stock  that may be  subject  to stock
options,  restricted stock awards and restricted stock unit awards is 1,000,000.
No one participant may receive awards  representing  more than 200,000 shares of
common stock in any one calendar year.

        ISOs and NQSOs  granted  under the 2005 Plan  generally  vest no earlier
than six months  after the date of grant and can be  exercised no later than the
tenth (10th) anniversary date of the date of grant. When the optionee,  however,
holds more than 10% of all combined  VOTING  stock of the Company,  ISOs granted
under the 2005 Plan cannot be exercised  later than the fifth (5th)  anniversary
date of the date of grant. The exercise prices of options granted under the 2005
Plan are set by the Board of Directors of the Company, or designated  committee,
however,  any options  granted under the 2005 Plan may not be  exercisable  at a
price lower than the fair market value of the Company's Common Stock on the date
such  options  are  granted,  and when the  optionee  holds more than 10% of all
combined  voting stock of the Company,  the exercise  prices of such options may
not be less  than  110% of the  fair  market  value of the  Common  Stock of the
Company on the date of grant.  ISOs granted  under the 2005 Plan to any optionee
that become  exercisable  for the first time in any one calendar year for shares
of Common Stock of the Company with an aggregate  fair market  value,  as of the
respective  date or dates of grant,  of more than  $100,000  shall be treated as
NQSOs.  The  options  under  the  2005  Plan  are  subject  to  restrictions  on
transferability, are forfeitable in certain circumstances and are exercisable at
such time or times and  during  such  period as shall be set forth in the option
agreement evidencing such option. Options intended to qualify as incentive stock
options may be granted only to persons who are our employees or are employees of
our  subsidiaries  which are  treated as  corporations  for  federal  income tax
purposes.  No  participant  may be  granted  incentive  stock  options  that are
exercisable  for the first time in any  calendar  year for common stock having a
total  fair  market  value  (determined  as of the  option  grant)  in excess of
$100,000.  The 2005 Plan  prohibits  repricing  of an  outstanding  option,  and
therefore,  the  administrator may not, without the consent of the shareholders,
lower the exercise price of an outstanding option.  Unless provided otherwise in
a  participant's  stock  option  agreement  and subject to the maximum  exercise
period for the option, an option generally will cease to be exercisable upon the
earlier of three months following the participant's  termination of service with
us or the  expiration  date under the terms of the  participant's  stock  option
agreement.  The  right to  exercise  an  option  will  expire  immediately  upon
termination  if the  termination is for "cause" or a voluntary  termination  any
time after an event that would be grounds for termination for cause.  Upon death
or disability, the option exercise period is extended to the earlier of one year
from the  participant's  termination of service or the expiration date under the
terms of the participant's stock option agreement.

        Awards of restricted  stock are rights to acquire or purchase  shares of
the Company's  Common Stock. A restricted  stock award may be subject to payment
by the participant of a purchase price for shares of common stock subject to the
award,  and may be subject to vesting  requirements or transfer  restrictions or
both, if so provided by the administrator.  Awards of restricted stock units are
dollar value  equivalents  of shares that vest in accordance  with the terms and
conditions  established  by the  administrator  in its  sole  discretion.  Those
requirements  may  include,  for example,  a  requirement  that the  participant
complete a specified period of service or that certain performance objectives be
achieved.  The typical award of restricted  stock or restricted stock units will
vest  ratably  over a two to  four  year  period  (25% to 50%  per  year).  Upon
satisfying the  applicable  vesting  criteria,  a participant is entitled to the
payout in accordance  with, and at the times specified in, the award  agreement.
The  administrator  may pay earned  restricted stock units in cash,  shares or a
combination of both.

        The 2005 Plan  also  contains  specific  performance  criteria  that the
Compensation  Committee  may  use  to  establish  performance  objectives,   the
achievement  of which may be conditions for certain awards to vest or be issued.
By subjecting the vesting to these performance  objectives,  the Company is able
to claim income tax  deductions for those awards without regard to the deduction
limitations under Section 162(m) of the Code.

                                       18



        As of the Record Date, 355,500 shares of the Company's Common Stock have
been reserved for issuance  upon the exercise of options  granted under the 2005
Plan,  inclusive  of stock  options to purchase  100,000  shares of Common Stock
issued under the 2005 Plan to a consultant during the fiscal year ended July 31,
2006.  In addition,  as of the Record Date,  the Board of Directors  has awarded
under the 2005 Plan (a) 10,000  restricted  stock units to the Lead  Independent
Director,  (b)  5,000  restricted  stock  units  to  each of the  other  Outside
Directors, and (c) 55,050 shares of restricted stock to various employees of the
Company.

INSURANCE FOR INDEMNIFICATION OF DIRECTORS AND OFFICERS

        The Company has in effect, with Darwin Professional  Underwriters,  Inc.
and XL Specialty  Insurance Company under a policy effective  February 22, 2006,
and expiring on February 21, 2007,  insurance  covering all of its directors and
officers and certain other employees of the Company against certain  liabilities
and reimbursing  the Company for obligations  which it incurs as a result of its
indemnification  of such directors,  officers and employees.  Such insurance has
been obtained in accordance  with the  provisions of Section 726 of the Business
Corporation Law of the State of New York. The annual premium is $360,000.

        This report has been provided by the Board of Directors of the Company.


                      Elazar Rabbani, Ph.D.
                      Shahram K. Rabbani
                      Barry W. Weiner
                      John J. Delucca
                      Irwin C. Gerson
                      Melvin F. Lazar, CPA
                      John B. Sias


PERFORMANCE GRAPH

        The graph below  compares the  five-year  cumulative  shareholder  total
return based upon an initial  $100  investment  (assuming  the  reinvestment  of
dividends)  for Enzo Biochem,  Inc.  shares of Common Stock with the  comparable
return for the New York Stock  Exchange  Market  Value Index and two peer issuer
indices selected on an industry basis.  The two peer group indices include:  (i)
60 biotechnology companies engaged in the research and development of diagnostic
substances and (ii) 10 companies engaged in the medical  laboratories  business.
All of the indices include only companies whose common stock has been registered
under  Section 12 of the  Securities  Exchange Act of 1934 for at least the time
frame set forth in the graph.

        The total shareholder  returns depicted in the graph are not necessarily
indicative of future  performance.  The Performance Graph and related disclosure
shall not be deemed to be incorporated by reference in any filing by the Company
under the Securities Act of 1933 or the Securities  Exchange Act of 1934, except
to the extent  that the  Company  specifically  incorporates  the graph and such
disclosure by reference.

                                       19



[GRAPHIC OMITTED]

              COMPARISON OF CUMULATIVE TOTAL RETURN OF ONE OR MORE
          COMPANIES, PEER GROUPS, INDUSTRY INDEXES AND/OR BROAD MARKETS

                         2001      2002      2003      2004      2005      2006
                        ------     -----    ------    ------    ------    ------
 ENZO BIOCHEM, INC.     100.00     55.21     86.51     56.92     73.56     56.51
MEDICAL LABORATORIES    100.00     70.18     74.61     82.01    104.97    130.89
 NYSE MARKET INDEX      100.00     80.95     88.81    101.83    120.44    130.75
BIOTECHNOLOGY PEERS     100.00     83.94    100.53    112.03    127.31    138.30

                                       20



                                   PROPOSAL 2
            APPROVAL OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

        The  Board  of  Directors  has  appointed  Ernst  &  Young  LLP,  as its
independent  registered  public  accounting  firm,  to audit the accounts of the
Company  for the  fiscal  year  ending  July 31,  2006.  The Board of  Directors
approved the  reappointment  of Ernst & Young LLP (which has been engaged as the
Company's  independent  registered public  accounting firm since 1983).  Ernst &
Young LLP has advised the Company  that  neither the firm nor any of its members
or  associates  has any direct  financial  interest in the Company or any of its
affiliates  other than as auditors.  Although the selection and  appointment  of
independent  auditors is not required to be submitted to a vote of shareholders,
the Directors  deem it desirable to obtain the  shareholders'  ratification  and
approval of this appointment.

        The  following  table sets forth the  aggregate  fees  billed by Ernst &
Young LLP for the years  ended  July 31,  2006 and 2005 for audit and  non-audit
services (as well as all "out-of-pocket" costs incurred in connection with these
services) and are  categorized as Audit Fees,  Audit-Related  Fees, Tax Fees and
All Other Fees.  The nature of the  services  provided in each such  category is
described following the table.

        ----------------------------------- -------------- --------------
                                                 2006           2005
                                              ----------       ------
        ----------------------------------- -------------- --------------
        AUDIT FEES                             $702,135       $667,500
        ----------------------------------- -------------- --------------
        AUDIT-RELATED FEES                        0                  0
        ----------------------------------- -------------- --------------
        TAX FEES                                  0                  0
        ----------------------------------- -------------- --------------
        ALL OTHER FEES                            0                  0
        ----------------------------------- -------------- --------------

        ----------------------------------- -------------- --------------
        TOTAL FEES                             $702,135       $667,500
                                               --------       --------
        ----------------------------------- -------------- --------------

        AUDIT FEES - Consists of fees for  professional  services  necessary  to
perform  an audit or review in  accordance  with the  Public  Company  Oversight
Board,  including  services  rendered  for the  audit  of our  annual  financial
statements  (including services incurred with rendering an opinion under Section
404 of the  Sarbanes-Oxley  Act of 2002) and quarterly  reviews of the Company's
interim  financial  statements.  Audit  fees  also  include  fees  for  services
performed by Ernst & Young LLP that are closely related to the audit and in many
cases  could  only be  provided  by the  Company's  independent  auditors.  Such
services include the issuance of consents related to the Company's  registration
statements and capital raising  activities,  assistance with and review of other
documents  filed  with  the  Commission  and  accounting   advice  on  completed
transactions.

        AUDIT RELATED FEES -- There were no  professional  services  rendered by
Ernst & Young LLP that would be  classified  as audit  related  fees  during the
years ended July 31, 2006 and 2005.

        TAX FEES - There were no professional services rendered by Ernst & Young
LLP that would be  classified  as tax fees  during the years ended July 31, 2006
and 2005.

        ALL OTHER FEES - There were no professional services rendered by Ernst &
Young LLP that would be classified as other fees during the years ended July 31,
2006 and 2005.

        Pre-Approval Policies and Procedures - The Audit Committee has adopted a
policy that requires advance approval of all audit, audit-related, tax services,
and other services performed by the independent auditor. The policy provides for
pre-approval by the Audit Committee of specifically  defined audit and non-audit
services.  Unless the specific  service has been  previously  pre-approved  with
respect to that year,  the Audit  Committee  must approve the permitted  service
before the independent auditor is engaged to perform it. The Audit Committee has
delegated to the Chair of the Audit  Committee  authority  to approve  permitted
services  provided  that the Chair reports any decisions to the Committee at its
next scheduled meeting.

        In making its recommendations to ratify the appointment of Ernst & Young
LLP as the Company's independent accountants for the fiscal year ending July 31,
2007, the Audit Committee has considered  whether the services provided by Ernst
& Young LLP are compatible with  maintaining  the  independence of Ernst & Young
LLP.

                                       21



        Representatives  of Ernst & Young LLP are  expected to be present at the
Annual Meeting with the  opportunity to make a statement if they desire to do so
and are expected to be available to respond to appropriate questions.

        THE BOARD OF DIRECTORS  RECOMMENDS  A VOTE "FOR"  PROPOSAL 2 RELATING TO
THE  RATIFICATION OF THE APPOINTMENT OF THE AUDITORS.  PROXIES  SOLICITED BY THE
BOARD OF DIRECTORS WILL BE SO VOTED UNLESS SHAREHOLDERS SPECIFY IN THEIR PROXIES
A CONTRARY CHOICE.

                                       22



                                     GENERAL

        The  Management  of the Company does not know of any matters  other than
those stated in this Proxy Statement which are to be presented for action at the
meeting.  If any other matters  should  properly come before the meeting,  it is
intended that proxies in the accompanying form will be voted on any such matters
in   accordance   with  the  judgment  of  the  persons   voting  such  proxies.
Discretionary  authority  to vote on such  matters is  conferred by such proxies
upon the persons voting them.

        The Company will bear the cost of preparing,  assembling and mailing the
Proxy,  Proxy Statement and other material which may be sent to the shareholders
in connection with this solicitation. In addition to the solicitation of proxies
by use of the mails,  officers and regular  employees  may solicit the return of
proxies.  The Company may reimburse  persons  holding stock in their names or in
the names of other  nominees  for their  expense  in sending  proxies  and proxy
material to principals. In addition, American Stock Transfer & Trust Company, 59
Maiden Lane, New York, New York 10038,  the Company's  transfer agent,  has been
engaged  to  solicit  proxies  on behalf  of the  Company  for a fee,  excluding
expenses,  of approximately  $5,000.  Proxies may be solicited by mail, personal
interview, telephone and telegraph.

        ENZO WEBSITE

        In addition to the  information  about the Company and its  subsidiaries
contained in this proxy statement,  extensive  information about the Company can
be found on our website located at www.enzo.com, including information about our
management team, products and services and our corporate governance practices.

        The  corporate  governance  information  on  our  website  includes  the
Company's Corporate Governance Guidelines,  the Code of Conduct and the charters
of each of the  committees  of the Board of  Directors.  These  documents can be
accessed  at  www.enzo.com.   Printed  versions  of  our  Corporate   Governance
Guidelines, our Code of Conduct and the charters for our Board committees can be
obtained,  free of charge, by writing to the Company at: 527 Madison Avenue, New
York, New York 10022, Attn: Corporate Secretary.

        This  information  about Enzo's  website and its content,  together with
other references to the website made in this proxy statement, is for information
only and the content of the Company's  website is not deemed to be  incorporated
by reference in this proxy  statement or otherwise filed with the Securities and
Exchange Commission.

        THE COMPANY WILL PROVIDE  WITHOUT CHARGE TO EACH PERSON BEING  SOLICITED
BY THIS PROXY STATEMENT,  UPON THE WRITTEN REQUEST OF ANY SUCH PERSON, A COPY OF
THE ANNUAL  REPORT OF THE  COMPANY ON FORM 10-K FOR THE YEAR ENDED JULY 31, 2006
(AS FILED WITH THE SECURITIES AND EXCHANGE  COMMISSION)  INCLUDING THE FINANCIAL
STATEMENTS AND THE SCHEDULES  THERETO.  ALL SUCH REQUESTS  SHOULD BE DIRECTED TO
SHAHRAM K. RABBANI, SECRETARY, ENZO BIOCHEM, INC., 527 MADISON AVENUE, NEW YORK,
NEW YORK 10022.


                      SHAREHOLDER PROPOSALS TO BE PRESENTED
                           AT THE NEXT ANNUAL MEETING

        Shareholder   Proposals.   Proposals  of  shareholders  intended  to  be
presented at the Company's 2007 Annual Shareholder  Meeting (i) must be received
by the Company at its  offices no later than August 6, 2007 (120 days  preceding
the one year anniversary of the Mailing Date), (ii) may not exceed 500 words and
(iii) must otherwise  satisfy the  conditions  established by the Securities and
Exchange  Commission for  shareholder  proposals to be included in the Company's
Proxy Statement and form of proxy for that meeting.

        Discretionary  Proposals.  Shareholders  intending to commence their own
proxy  solicitations  and  present  proposals  from the floor of the 2007 Annual
Shareholder Meeting in compliance with Rule 14a-4 promulgated under the Exchange
Act of 1934,  as  amended,  must notify the  Company of such  intentions  before
October 22, 2007 (the first  business day  following 45 days  preceding  the one
year  anniversary of the Mailing Date).  After such date, the Company's proxy in
connection  with the 2006 Annual  Shareholder  Meeting may confer  discretionary
authority on the Board to vote.

                                       23



                                        By Order of the Board of Directors


                                        Shahram K. Rabbani, SECRETARY



Dated: December 4, 2006

                                       24



                                      PROXY

                               ENZO BIOCHEM, INC.
                               527 MADISON AVENUE
                            NEW YORK, NEW YORK 10022

           THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

        The undersigned  hereby  appoints  Elazar  Rabbani,  Ph.D. and Melvin F.
Lazar as  Proxies,  each with the power to appoint  his  substitute,  and hereby
authorizes them to represent and to vote, as designated below, all the shares of
the Common Stock of Enzo  Biochem,  Inc.  held of record by the  undersigned  on
November 27, 2006, at the Annual Meeting of  Shareholders  to be held on January
23, 2007 or any adjournment thereof.

PROPOSAL 1.      Election of Irwin C. Gerson and Shahram K. Rabbani as
                 Class I Directors.

                 |_| FOR all nominees (except   |_| WITHHOLDING AUTHORITY
                     as marked to the               (as to all nominees)
                     contrary below)
                 (INSTRUCTION: To withhold authority to vote for any individual
                 nominee, print that nominee's name on the line provided below.)


                 Withheld for: _____________________________________________



PROPOSAL 2.      To  ratify  the  appointment  of  Ernst & Young  LLP as the
                 Company's  independent  registered  public accounting firm for
                 the Company's fiscal year ending July 31, 2007.

                 |_| FOR                  |_| AGAINST            |_| ABSTAIN

        In their discretion,  the Proxies are authorized to vote upon such other
business  as may  properly  come  before  the  Annual  Meeting.  This proxy when
properly executed will be voted in the manner directed herein by the undersigned
shareholder.  If no direction is made,  this proxy will be voted FOR Proposals 1
and 2.

                                       25



        PLEASE SIGN EXACTLY AS NAME APPEARS  BELOW.  WHEN SHARES OF COMMON STOCK
ARE HELD BY JOINT TENANTS, BOTH SHOULD SIGN.



               Dated:___________________________ , 2006 / 2007 (circle one)



               Signature:______________________________



               Signature if held jointly: ______________________________
               (When signing as attorney, as executor, as administrator, trustee
               or guardian,  please give full title as such.  If a  corporation,
               please  sign  in  full  corporate  name  by  President  or  other
               authorized officer. If a partnership,  please sign in partnership
               name by authorized person.)

                                       26