Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
William Blair Capital Management VII, LLC
  2. Issuer Name and Ticker or Trading Symbol
CRYOCOR INC [CRYO]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
303 W. MADISON SUITE 2500
3. Date of Earliest Transaction (Month/Day/Year)
05/28/2008
(Street)

CHICAGO, IL 60606
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 05/28/2008   U   1,944,961 (1) D $ 1.35 0 I By Partnership (2) (3)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Non-qualified Stock Option (right to buy) (4) $ 6.69 05/28/2008   D     6,451   (5) 05/13/2017 Common Stock 6,451 $ 0 0 I (6) See Footnote (6)
Non-qualified Stock Option (right to buy) (4) $ 2.35 05/28/2008   D     6,451   (5) 05/02/2016 Common Stock 6,451 $ 0 0 I (6) See Footnote (6)

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
William Blair Capital Management VII, LLC
303 W. MADISON SUITE 2500
CHICAGO, IL 60606
    X    
William Blair Capital Management VII, LP
303 W. MADISON SUITE 2500
CHICAGO, IL 60606
    X    
BLAIR WILLIAM CAPITAL PARTNERS VII QP LP
303 W. MADISON SUITE 2500
CHICAGO, IL 60606
    X    
BLAIR WILLIAM CAPITAL PARTNERS VII LP
303 W. MADISON SUITE 2500
CHICAGO, IL 60606
    X    

Signatures

 Arda M. Minocherhomjee, Managing Director of William Blair Capital Management VII, L.L.C.   05/22/2007
**Signature of Reporting Person Date

 Arda M. Minocherhomjee, Managing Director of William Blair Capital Management VII, L.L.C., the general partner of William Blair Capital Management VII, L.P.   07/19/2005
**Signature of Reporting Person Date

 Arda M. Minocherhomjee, Managing Director of William Blair Capital Management VII, L.L.C., the general partner of William Blair Capital Management VII, L.P., the general partner of William Blair Capital Partners VII, QP, L.P.   07/19/2005
**Signature of Reporting Person Date

 Arda M. Minocherhomjee, Managing Director of William Blair Capital Management VII, L.L.C., the general partner of William Blair Capital Management VII, L.P., the general partner of William Blair Capital Partners VII, L.P.   07/19/2005
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Represents 1,872,801 shares beneficially owned by William Blair Capital Partners VII QP, LP and 72,160 shares beneficially owned by William Blair Capital Partners VII LP.
(2) The amounts shown in Table I and II represent the beneficial ownership of the Issuer?s equity securities by William Blair Capital Partners VII QP, L.P. and William Blair Capital Partners VII, L.P., a portion of which may be deemed attributable to William Blair Capital Management VII, L.L.C. and William Blair Capital Management VII, L.P., because William Blair Capital Management VII, L.P. is the general partner of William Blair Capital Partners VII QP, L.P. and William Blair Capital Partners VII, L.P. and William Blair Capital Management VII, L.L.C. is the general partner of William Blair Capital Management VII, L.P. The actual pro rata portion of such beneficial ownership that may be deemed attributable to such Reporting Person is not readily determinable because it is subject to several variables.
(3) The Designated Filer is executing this report on behalf of William Blair Capital Management VII, L.L.C., William Blair Capital Management VII, L.P., William Blair Capital Partners VII QP, L.P. and William Blair Capital Partners VII, L.P. (collectively, the "Reporting Persons"), each of whom has authorized it to do so; each of the Reporting Persons disclaim beneficial ownership of the Issuer?s securities to the extent it exceeds such Reporting Person?s pecuniary interest.
(4) The Designated Filer is executing this report on behalf of William Blair Capital Management VII, L.L.C., William Blair Capital Management VII, L.P., William Blair Capital Partners VII QP, L.P. and William Blair Capital Partners VII, L.P. (collectively, the "Reporting Persons"), each of whom has authorized it to do so.
(5) This option will vest and become exercisable ratably on a monthly basis over a one-year period, beginning one month from date of grant.
(6) Represents an option granted to Arda Minocherhomjee, a Director of the Issuer. Pursuant to contractual arrangements between Mr. Minocherhomjee and William Blair Capital Management VII, L.P. and among the Reporting Persons, the Reporting Persons may be deemed to have a pecuniary interest in such option. Each of the reporting Persons disclaims beneficial ownership of such option and the Issuer?s other securities except to the extent of its pecuniary interest therein.

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